Protein Alignment Nepl18 and Nepl7

DIOPT Version :10

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_609577.2
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Alignment Length: 754
• Identity: 189/754 - (25%)
• Similarity: 308/754 - (40%)
• Gaps: 167/754 - (22%)

  Fly     7 LWLCLL-VAIVPAMAKPSDAGDPFA--------DDLTSDYAKKIIVQAKVAEMKTMMKPEVSPCD 62
            ||..|: :.::..:.    |.|.|:        :::..||.:.::         :.|...:.||:
  Fly     5 LWATLISLTLIGRVL----ANDLFSLPPATNHREEMLEDYGRFLL---------STMNRTIDPCE 56

  Fly    63 DFYTHACGNWHRHN--PAQLLGDVMTDNFKLISKGFDRRLQRLLRANDLQSELEK---------- 115
            :||..:||.|.:.:  |.|...   |.....|....|.::|..|: |..:.|||.
  Fly    57 NFYEFSCGGWKKADLVPEQARN---TSFLNAIQHKIDEQIQGFLQ-NATKRELEDLGVNGTTSAE 117

  Fly   116 -KMQRFYMSC-----NLVHRDDVHYKLALE---NVIREYGTLPALVGAQWNSSDFSWWRTVAQIQ 171
             |.::||.||     ||    .:.|:..:|   :.::|            .::.:.|  ......
  Fly   118 IKAKQFYASCVEMKANL----SLGYQYFMEHDGDRLKE------------RNATYDW--MYINFM 164

  Fly   172 HKYGKQIIIGLEIMH-------DIRNTSVNRVYISQPDFKTINTRLTNLMEEVRTSMDLQQYFGL 229
            .||....::.|::.:       ||..|..::|             |....||...:|..:  |||
  Fly   165 SKYDIYPLLALKVHYSTSSRKFDILLTLPSKV-------------LAGFSEEQLKNMTRE--FGL 214

  Fly   230 SSSVAK-----HTAEQLTELERTFSSGGSGAATLQESLSLYTVADLQEKYSDHLNFTEFLGL--- 286
            .||..|     .....||:.||...   |.|.:..|:..|.....|.:...|.||:|.|..|
  Fly   215 DSSAEKVKQFVENFNNLTQFERNLV---SLAKSRNETEQLNFKEFLVKHKHDRLNWTRFFELAFN 276

  Fly   287 --------ILGE-ENIPKSLYIYDEEYLD--KALLTMRSTPLATQANYVLWKLLEDFLVDAQPKD 340
                    :|.: :||...::..::..|:  |..:.||.    ....|.|||      ...:...
  Fly   277 GSQESHWPVLNQLDNINDLVFFLEQTNLETLKGYIKMRE----LVKFYGLWK------TQTKTGG 331

  Fly   341 MVKWCTESTKKYF---------GKLAEHAVYKRYRNPDVESEVHKIWDQIKGIFRQRLLGDKLDW 396
            :...|...::.||         ||     |:.:.|..|:.|    :...||..|...|  |...|
  Fly   332 VQSECRSLSETYFNYALLPWFIGK-----VFDKERRADILS----VAKDIKDTFYDLL--DHHTW 385

  Fly   397 ISNATRTLAIEKLERMHLNINSYDEENFENVYGEVFIDRLNYVSN-VQQLLIAKGIRFVARINQP 460
            :...||:.|..||..|.:.:...|:.....|...|:.| :|...| .:.|.|.:|.|...|:.
  Fly   386 LDEDTRSQAKTKLASMDILVGYTDDLQHREVIDGVYSD-INMTGNWFENLCILEGSRARIRLR-- 447

  Fly   461 ADSVDATELLGFTP-----AYNIQENNIT-IPVALLQPRYFWGDQYPEALKYATLGYLLAHEMLH 519
              |||...:....|     ||.....|:. |.:.:.|..::..| :|:.||||.:|.::.|||.|
  Fly   448 --SVDKALIPLLMPTRTVNAYYADFLNLAFITIGMAQWPFYHID-FPDVLKYAGVGNIIGHEMAH 509

  Fly   520 GFDDDGRQYDASGNLAPWWDLKSRYEFEERRKCFQAQYHEYQYGGSKLPESKDQSENIADSGGLK 584
            |||....||:..|....||...|...|:||.:|.::||:::...|.:...|....:||||:.|.:
  Fly   510 GFDSYCYQYNYDGKKTNWWSSASLRNFKERYRCLESQYNKFILMGVQTNGSLTSGDNIADNVGTR 574

  Fly   585 LAYAAYELWLGQQSEEVLQRETMEGLPFNSRQLFFLGYAQLLC------DDVQFLFQPWVSQSDR 643
            :||.|::...|   ::....:.:.|:.||::||||:.:||..|      |.::.|      ::|.
  Fly   575 MAYYAFKRKTG---DKAWLEKPLRGVNFNNKQLFFVKFAQTWCNGKDNGDKLRRL------KTDV 630

  Fly   644 HAPSKYRVIGPLSNFQEFPWVFNCSQSAPMDPEYKCAIY 682
            ||..::||.|.|||..||...|||.....|:|..||.::
  Fly   631 HAYDEFRVQGTLSNMPEFSEAFNCKLGTEMNPLKKCVVW 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	M13	58..679	CDD:341056	178/689 (26%)
Nepl7	NP_609577.2	M13	52..666	CDD:341056	178/689 (26%)