Protein Alignment Nepl18 and Nep3

DIOPT Version :10

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Alignment Length: 753
• Identity: 185/753 - (24%)
• Similarity: 316/753 - (41%)
• Gaps: 138/753 - (18%)

  Fly    29 FADDLTSDYAKKII-VQA--------------------KVAEMKTMMKPEVSPCDDFYTHACGNW 72
            |.|..:||..|.:: ||.                    ..:|:...:...|.||||||.::|..|
  Fly    73 FTDGGSSDATKHVLHVQPHQKDCPSGNELPCLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQW 137

  Fly    73 HRHNPAQLLGDVMTDNFKLISKG---------FDRRLQRLLR------ANDLQSELEKKMQRFYM 122
            .::||              |.:|         .::..|.::|      |...:|:.|:|.:.:|.
  Fly   138 IKNNP--------------IPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYE 188

  Fly   123 SCNLVHRDDVHYKLA---LENVIREYGTLPALVGAQWNSSDFSWWRTVAQIQHKYGKQIIIGLEI 184
            ||  :..|:...||.   :.:::.:.|.. .:..:.:|.::::...|:..:.:||....:.|..|
  Fly   189 SC--LDADEHMEKLGAKPMNDLLLQIGGW-NVTKSGYNVANWTMGHTLKILHNKYNFNCLFGWAI 250

  Fly   185 MHDIRNTSVNRVYISQ-----PDFKTINTRLTN----LMEEVRTSMDLQQYFGLSSSVAKHTAEQ 240
            ..|.:|:|.:.:.|.|     |.....|.:..|    |.|.:.....:....|.:.|.|:.....
  Fly   251 GEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIG 315

  Fly   241 LTELERTFSSGGSGAATLQESLSLYTVADLQE--------KYSDHL-NFTEFLGLILGEENIPKS 296
            :...|:..::........:...::|....|::        .::||. |..:.:|..:.::.:
  Fly   316 VINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEV--- 377

  Fly   297 LYIYDEEY---LDKALLTMRSTP--LATQANYVLWKLLEDF-------LVDAQP----------- 338
            :.:|..::   |...:|.|..|.  ..|..||::|:.:...       ..||..
  Fly   378 VVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDG 442

  Fly   339 -KDMVKWCTESTKKYFGKLAEHAVYKRY-----RNPDVESEVHKIWDQIKGIFRQRLLGDKLDWI 397
             :::.::|...|....| .|..|::.|.     ..|..|..:    .:|:..|:..|  ..|.|:
  Fly   443 GEEIWRYCVSDTNNVVG-FAVGAIFVRQAFHGESKPAAEQMI----AEIREAFKMNL--QNLTWV 500

  Fly   398 SNATRTLAIEKLERMH--LNINSY--DEENFENVYGEVFIDRLNYVSNVQQLLIAKGIRFVARIN 458
            ...||..||||..::.  :....|  |....:..|.|:.|....|..|..|:.|......:.|::
  Fly   501 DKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLD 565

  Fly   459 QPADSVDATELLGFTPA-----YNIQENNITIPVALLQPRYFWGDQYPEALKYATLGYLLAHEML 518
            ||.:..:    .|.||.     |...:|.|..|..:||..:| ....|::|.:..:|.::.||:.
  Fly   566 QPVNKTN----WGMTPQTVNAYYTPTKNQIVFPAGILQTPFF-DINNPKSLNFGAMGVVMGHELT 625

  Fly   519 HGFDDDGRQYDASGNLAPWWDLKSRYEFEERRKCFQAQYHEYQYGGSKLPESKDQSENIADSGGL 583
            |.|||.||:||..||:..|||.||...|.|:.:|...||..|:..|..|...:...|||||:|||
  Fly   626 HAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGL 690

  Fly   584 KLAYAAYELWLGQQSEEVLQRETMEGLPFNSRQLFFLGYAQLLC----DDVQFLFQPWVSQSDRH 644
            |.||.||:.....:..::|:   :.||.....||||:.:||:.|    |:...|    ..:.|.|
  Fly   691 KAAYHAYQRTKSDRDVDILK---LPGLNLTHSQLFFVSFAQVWCSSTTDETNLL----QMEKDPH 748

  Fly   645 APSKYRVIGPLSNFQEFPWVFNCSQSAPMDPEYKCAIY 682
            :||::||||.|||.:||..||.|.....|:|..||.::
  Fly   749 SPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	M13	58..679	CDD:341056	175/698 (25%)
Nep3	NP_523417.2	M13	123..784	CDD:341056	176/699 (25%)