Protein Alignment Nepl18 and Nep6

DIOPT Version :9

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_001245645.1
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 687
• Identity: 173/687 - (25%)
• Similarity: 266/687 - (38%)
• Gaps: 131/687 - (19%)

  Fly    57 EVSPCDDFYTHACGNWHRHNPAQLLG--DVMTD---NFKLISKGFDRRLQRLLR---------AN 107
            ||.||::|:.:|||||:.:...::||  |:.:.   |.||       :|.|.|.         ||
  Fly    39 EVKPCENFHQYACGNWYSNTSQRILGAHDMRSKWVANLKL-------QLIRYLEESSSTDSFSAN 96

  Fly   108 DLQSELEKKMQRFYMSCNLVHRDDVHYKLALENVIREYGTLPALVGAQWNSSDFSWWRTVAQIQH 172
            ...:....::...|..|.|..:....|..||.   |.....|.|  |......|.|....|.::
  Fly    97 TSVTTSTAQLGTLYRCCLLSGQSIRTYTDALS---RSGANFPLL--ANHTGGSFDWVLANAALR- 155

  Fly   173 KYGKQIIIGLEIMHDIRNTSVNRVYISQPDFKTINTRLTNLMEEVRTSMDLQQY-------FGLS 230
            .||.|.:..|.:..:.::......|:..|.|..:. |...|.|.:     .|:|       .||.
  Fly   156 TYGAQGLWRLLVKDNWQSADQRIFYMLPPKFDLLG-RDDELNEFL-----YQRYLKILLLELGLR 214

  Fly   231 SSVAKHTAEQLTELERTFS----SGGSGAATLQESLSLYTVADLQEKYSDHLNFTEFLGLILGEE 291
            ...|...||:|...|::..    :.......|::..||   .|| |.....|....:...||  |
  Fly   215 VRRAALLAEKLVAFEKSLQKLLPNDAEQTLVLRKPQSL---KDL-ESQLPRLELKRYFETIL--E 273

  Fly   292 NI----PKSLYIYDEEYLD--KALLTMRSTPLATQANYVLWKLLEDFLVDAQPKDMV----KWCT 346
            .|    ...|.:.|.:||.  :.||...::.....:.::|.:|...|.:.....|.:    ..|.
  Fly   274 GIDWDSKTLLLVADLDYLQGLQRLLAEHTSDPMVLSTWLLLQLPAYFELRLHDDDKLGNQRNHCL 338

  Fly   347 ESTKK----YFGKLAEHAVY-KRYRNPDVESEVHKIWD----QIKGIFRQRLLGDKLDWISN--- 399
            |..:|    ..|:|....|. :.|::         ::|    ||..:||.  |..:.:.:.|
  Fly   339 EQLRKLMPGQLGRLQMQLVLGESYQD---------VYDTAIQQIAVLFRD--LKQQFELVLNETE 392

  Fly   400 ------ATRTLAIEKLERMHLNINSYDEENFENVYGEVFIDRL--NYVSNVQQLLIAKG-IRFVA 455
                  .||.||.:||..|.|......:.    :.|.....:|  |..:|:.||.:::. :.:..
  Fly   393 VFNEDLVTRNLARDKLRAMRLLTPRLQDP----INGGPGTPQLGGNCDANLLQLSLSQAKLEYRQ 453

  Fly   456 RINQPADSVDATELLGFTPAYNIQENNITIPVALLQPRYFWGDQYPE----ALKYATLGYLLAHE 516
            ...:|..||.| :.|.....|.::.|.|.:|:.|:...........|    |...|.|||:||||
  Fly   454 VFGEPVTSVPA-DPLSVNAYYRLKLNRIELPLGLMATPLIQQQCSKEADTRAKLSAGLGYILAHE 517

  Fly   517 MLHGFDDDGRQYDASGNLA-PWWDLKSRYEFEERRKCFQAQYHEYQYGGSKLPESKDQSENIADS 580
            |:|.||.||..|||:|.|| ..|..::...|..|..|    |...:|..:.|    ..:|||||:
  Fly   518 MVHAFDLDGLNYDATGQLANGQWSARAIIRFGLRAGC----YLGVRYSNATL----TVNENIADT 574

  Fly   581 GGLKLAYAAYELWLGQQSEEVLQRETMEGLPFNSRQLFFLGYAQLLCDDVQFLFQPWVSQSDRHA 645
            .||:||...|....|.                .:.:.||:.:||..|..|..     .|...:||
  Fly   575 EGLRLALDTYRHRSGA----------------TNLRTFFVAFAQNWCGTVAS-----TSGLSQHA 618

  Fly   646 PSKYRVIGPLSNFQEFPWVFNCSQSAPMDPEYKCAIY 682
            ....||...:.|..||...|.|..::.|:|..||.|:
  Fly   619 GHAERVNNVVGNMPEFGDTFECKATSQMNPVNKCHIW 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	PepO	54..682	CDD:226118	172/685 (25%)
		M13	58..679	CDD:189000	169/681 (25%)
Nep6	NP_001245645.1	PepO	35..655	CDD:226118	172/685 (25%)
		M13	40..653	CDD:189000	170/682 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454932
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850