Protein Alignment Nepl18 and frma

DIOPT Version :9

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Alignment Length: 716
• Identity: 157/716 - (21%)
• Similarity: 287/716 - (40%)
• Gaps: 186/716 - (25%)

  Fly    40 KIIVQAKVAEMKTMMKPEVSPCDDFYTHACGNWHRHNPAQLLGDVMTDNFKLISKGFDRRLQRLL 104
            ::||...|.::|:  .|:..||.:||..|||||...:        .||:::......|...|..|
  Fly     9 ELIVGLLVVQVKS--HPQADPCQNFYKVACGNWSASH--------ATDSYESFMDRLDYNYQEKL 63

  Fly   105 RANDLQSELE-------KKMQRFYMSCNL-VHRDDV----HYKLALENVIREYGT--------LP 149
             |:.|.:|.|       ::::.||.:|.. :.:|.|    .:.:.:||:..|..:        |.
  Fly    64 -ADLLDNEREDDEPHFLQQLRNFYTACRKPLSQDQVLRILEHLIVMENIQNEELSVGLTAAFRLQ 127

  Fly   150 ALVGAQWNSSDFSWWRTVAQIQHKYGKQIIIGLEIMHDIRNTSVNRVYISQPDFKTINTRLTNLM 214
            .|:... :|:.:..|:.:  :.|:           .|...||: ||..:::..|..:...|..:
  Fly   128 VLIDLN-DSNTYDIWKQL--MSHR-----------KHWDPNTT-NREPLTREMFDKLWASLPKI- 176

  Fly   215 EEVRTSMDLQQYFGLSSSVAKHTAEQLTELERTFSSGGS------------------------GA 255
                 ....::|:.          .:|:|||....|.||                        |.
  Fly   177 -----PFPFKEYYW----------RELSELEEKIMSYGSEDDGFDSGDLVTRIPPFWMMPWPNGN 226

  Fly   256 ATLQESLSLYTVADLQEKYSDHLNFTEFLGLILGEENIPKSLYIYDEEYLDKALLTMRSTPLATQ 320
            .| .|:||       |..:...:...||:           ..|||           ||...:|..
  Fly   227 IT-YENLS-------QMAHWLDIKANEFI-----------LTYIY-----------MRLKLVAEG 261

  Fly   321 ANYVLWKLLEDFLVDAQPKDMVKWCTESTKKYFGKLAEHAVYKRYRNPDVESEVHKIWDQIKGIF 385
            .:...|.:..|            .|.|.:::.....|...|.|.:.....|..:..|:.::|..|
  Fly   262 VSTESWHIDRD------------QCAEQSRQILSHPAAWLVEKNHPRLKEEPVLQDIFAELKQRF 314

  Fly   386 RQRLLGDKLDWISNATRTLAIEKLERMHLNI-----NSYDE---ENFENVYGEVFIDRLNYVSNV 442
            .|:||.::.:: :.:|:...:.||:||.|.:     ||..:   ...|..|.:|.::..:|..|:
  Fly   315 GQKLLANRNNF-TRSTQHFLLGKLKRMRLRLSILPRNSSAQSMVRRIERHYRDVHMNASDYFGNL 378

  Fly   443 --------------QQLLIAKGIRFV-ARINQPADSVDATELLGF----TPAYNIQENNITIPVA 488
                          |...|..|.:.: :||::  ..:..|::.|:    :..|.:::|.:.:|::
  Fly   379 HIGLNHSRSHKKYAQLWAIVFGRQLIPSRISK--SDLYPTQVRGYGTYASAFYIVKQNMLIVPLS 441

  Fly   489 LLQPRYFWGDQYPEALKYATLGYLLAHEMLHGFDDDGRQYDAS--GNLAPWWDLKSRYEFEERRK 551
            ||:|.::...| |..|.|:.||::|.||:.||||.:|..:.:.  |:.|...:|.....|::...
  Fly   442 LLEPPFYTHGQ-PSILTYSALGFILGHELSHGFDSEGMTFSSHGVGSSAVDRELDRNPRFQQELG 505

  Fly   552 CFQAQYHEYQYGGSKLPESKDQSENIADSGGLKLAYAAYELWLGQQSEEVLQRETMEGLPFNSRQ 616
            |.:.::...:|            |..||:.||:|||:||  :...|::....|...|.:  ..:|
  Fly   506 CLRRRFGRKRY------------EKFADASGLELAYSAY--FDTAQTDHKRNRSAEELV--TQKQ 554

  Fly   617 LFFLGYAQLLCDDVQFLFQPWVSQSDRHAPSKYRVIGPLSNFQEFPWVFNCSQSAPMDPEYKCAI 681
            .||..:||..|.|.:.|      |:..|...:.||...:::|:.|...|:|   .|.....:|.:
  Fly   555 QFFHNFAQFFCSDKELL------QAHDHGSDRKRVNDAVAHFEPFREAFSC---GPSPRRRQCRL 610

  Fly   682 Y 682
            |
  Fly   611 Y 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	PepO	54..682	CDD:226118	152/700 (22%)
		M13	58..679	CDD:189000	150/693 (22%)
frma	NP_572226.2	GluZincin	25..601	CDD:301352	149/686 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454908
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940