Protein Alignment Nepl18 and nep-24

DIOPT Version :9

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_503005.3
• Gene: nep-24 / 190993
• WormBaseID: WBGene00013786
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 561
• Identity: 121/561 - (21%)
• Similarity: 232/561 - (41%)
• Gaps: 110/561 - (19%)

  Fly    56 PEVSPCDDFYTHACGNWHRHNPAQLLGDVMTDNFKLISKGFDRRLQRLLRANDL-QSELEKKMQR 119
            |.|.|||:|:..|||..|.|...    |:.|...|.|    :..::|.|:.|:. :|:.|..|:.
 Worm    56 PSVDPCDNFHQFACGREHEHETE----DIYTKKTKTI----NNIMKRFLKKNETSRSKSENAMRT 112

  Fly   120 FYMSCNLVHRDDVHYK-LALENVIREYGTLPA--LVGAQWNSSDFSWWRTVAQIQHKYGKQIIIG 181
            .|.:|..:.::....: .||:::.::..::.|  :|..:|:.|.|
 Worm   113 LYKACKTLEKNSTASRNKALQDIFQDIQSIGAWPVVDDKWDESKF-------------------- 157

  Fly   182 LEIMHDIRNTSVNRVYISQPDF------KTINTRLTNLMEEV--RTSMDLQQYFG---LSSSVAK 235
                 |:.:..||.|.:.:.:|      :.:|.|...:..|.  |.::||.:...   .::||..
 Worm   158 -----DLNDFLVNLVRLGRKNFGLFQMARYVNVRNFAIGPEAAWRHNVDLGKTISEILKANSVQT 217

  Fly   236 HTAEQLTELERTFSSGGSGAATLQESLSLYTVADLQEKY-----SDHLNFTEFLGLILGEENIP- 294
            :..:.|.:|        :....|:::||.:....:|..|     ||.::...|..|:| |...|
 Worm   218 NNKKLLDDL--------AEYVNLEKALSQHKFNTVQPGYIFSERSDFVSSVNFSRLVL-EMMSPD 273

  Fly   295 -KSLY--IYDEEYLDKALL----------TMRSTPLATQANYVLWKLLEDFLVDAQPKDMVKWCT 346
             ::|:  :|...||....|          .:|:|.....|||:::|.::..:.|........:|.
 Worm   274 KRTLFPEVYQIMYLTNTSLFFGKNNNLETIIRNTSKRALANYLIFKFIDTSIADLTYGSPSAFCE 338

  Fly   347 ESTKKYFGKLAEHAVYKRYRNPDVESEVHKIWD--QIKGIFRQRLLGDKLDWISNATRTLAIEKL 409
            :....:..:.|..|.|:.:.:.:...::.|:.:  |::.:   :::| ..||:|..::.:|::::
 Worm   339 QKVINFLPRAALRAFYRNFISKENRKKITKLTEATQVQLL---KIIG-ATDWMSIKSKKIAMDRV 399

  Fly   410 ERMHLNINSYDEENFENVYGEV--FIDRLNYVSNVQQLLIAKGIRFVARINQPADSVDATELLGF 472
            ..|::.|...|   :.:..|::  ..:.||..|:.....:      |.:||:.....:.....|.
 Worm   400 SSMNMVIGYPD---YFDPPGKLDGLFEHLNLSSSDTYYTV------VRKINRFMREQEMDYYTGE 455

  Fly   473 TP------------AYNIQENNITIPVALLQPRYFWGDQYPEALKYATLGYLLAHEMLHGFDDDG 525
            .|            .||..:||:.|........:| ...:|:....|.....|||||.|.|....
 Worm   456 VPYYPLFPGLMTNAMYNANDNNLMIFAPFFDDPFF-DSSFPDYANIAFTSNTLAHEMGHTFSPHL 519

  Fly   526 RQYDASGNLAPWWDLKSRYEFEERRKCFQAQYHEY---QYG 563
            ... .:|....|...|...|:|:|.||.:.||.||   :||
 Worm   520 MDI-MTGTTEVWLTPKETEEYEKRVKCLEDQYTEYDDPEYG 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	PepO	54..682	CDD:226118	121/561 (22%)
		M13	58..679	CDD:189000	120/559 (21%)
nep-24	NP_503005.3	GluZincin	58..561	CDD:301352	120/559 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920