Protein Alignment Nepl18 and nep-20

DIOPT Version :9

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_001317749.1
• Gene: nep-20 / 188176
• WormBaseID: WBGene00020293
• Length: 834
• Species: Caenorhabditis elegans
• Alignment Length: 763
• Identity: 142/763 - (18%)
• Similarity: 263/763 - (34%)
• Gaps: 211/763 - (27%)

  Fly     6 VLWLCLLVAIVPAMAKPSDAGDPFADDLTSDYAKKIIVQAKVAEMKTMMKPEVSPCDDFYTHACG 70
            :.||.|.:. .....|||....|....|             ..|:.......||.|.:||...||
 Worm   197 LFWLLLFIG-ARQDEKPSLCESPQCITL-------------AFELSAYQDTSVSKCHNFYKATCG 247

  Fly    71 NWHRHNPAQLLGDVMTDNFKLISKGFDRRLQRLLRAND--LQSELEKKMQRFYMSCNLVHRDDVH 133
            .:..|   |.|........|.:.|   |.::..||.|:  :.|:.|..::..:..||...::..:
 Worm   248 KYKHH---QALDKHRDAKKKEVVK---RIVREFLRRNESSITSKFEPAIRLMFGKCNKFSQNKTY 306

  Fly   134 YKLALENVIREYGTLPAL----VGAQWNSSD------------------------FSWWRTVAQI 170
              |.:...|.:.|..|.|    |...:|.:|                        |..:..:|..
 Worm   307 --LDIFKDIEKIGPWPVLKSDWVDVMFNLNDYLLSLVELGFTDFGLFKLEFRQLAFGQFPVIAPS 369

  Fly   171 QHKYGKQI--IIGLEIMHDIRNTSVNRVYISQPDFKTINTRLTNLMEEVRTSMDLQQYFGLSSSV 233
            :.|.|.|:  || |||:      ..|.|   |.|    ..:|:..:.|........::..|..:.
 Worm   370 EQKQGNQLEKII-LEIL------EANGV---QAD----RQKLSKYLREYSEFKSQLRHMSLEGTS 420

  Fly   234 AKHTAEQLTELERTFSSGGSGAATLQESLSLYTVADLQEKYSDHL---NFTEFLGLILGEENIPK 295
            .|:.....:.|....|      |.:|:...:.|.:.|..:....:   |.:.|.|
 Worm   421 VKYIRYNASTLSVNIS------ALVQKMAPMSTSSGLVRRIQSGILITNSSSFFG---------- 469

  Fly   296 SLYIYDEEYLDKALLTMRSTPLATQANYVLWKLL--------------EDFLVDAQPKD------ 340
                   :.||..:   :.|...|.|||:::..:              |..|:|..|:.
 Worm   470 -------KNLDAII---QQTHKRTLANYLIFHFIDAVTFDLTSGAKHSEHTLIDLLPRGSLQVLS 524

  Fly   341 -----------MVKWCTESTKKYFGKLAE-------HAVYKRYRNPDVESEVHKIWDQIKGIFRQ 387
                       ||:...:..|.....::|       |.|::       |.|..|:..:::.|
 Worm   525 QDFVDEEDQGVMVEMAKDLKKHVVEMISEGSSLDKGHLVFE-------EKERRKLIRKVQDI--- 579

  Fly   388 RLLGDKLDWISNATRTLAIEKLERMHLNINSYDEENFENVYGEVFIDRLNYVSNVQQLLIAKGIR 452
                            |.:.|.....||      :|||.:       .|.|..::.: :|.|..|
 Worm   580 ----------------LVVTKYPLEILN------QNFEKL-------NLTYSDSLHK-IIQKLRR 614

  Fly   453 FVAR--INQPADSVDATELLGFTPAYNIQENNITIPVALLQPRYFWGDQYPEALKYATLGYLLAH 515
            |.:.  |......:|.|:...:..|:..|..|..|.:|.:....::...||..:....:|::::.
 Worm   615 FRSEQLIEYLGGDLDPTDKGMWGSAHYEQATNDLIIIAPIIDGPYFDTSYPNYVNIFFMGFIISR 679

  Fly   516 EMLHGFDDDGRQYDASGNLAPWWDLKSRYEFEERRKCFQAQYHEYQYGGSKLPESKDQSENIADS 580
            |:....|....:.|..|:...|...:|...|:...||::          .|:..::..:|.:||.
 Worm   680 ELGRSLDSVRIRKDEKGHTENWLKSESLKRFDNNVKCWR----------KKITGTRFLNEMLADH 734

  Fly   581 GGLKLAYAAYELWLGQQSEEVLQR------ETMEGLPFNSRQLFFL-----GYAQLLCDDVQFLF 634
            .|.:.::.|.:.|..:.:..::::      .|||.:.|:.:.|:|.     ...:|...|.:..:
 Worm   735 VGHEASFMALKKWEKEMNGTIVEKIRGYESMTMEQIFFHLQALYFCRPPGGSTGELTAKDARQHY 799

  Fly   635 QPWVSQSDRHAPSKYRVIGPLSNFQEFPWVFNCSQSAPMDPEYKCAIY 682
            ...|:::.::.|             :|...|.||.:..|:.:.||..:
 Worm   800 STRVNEAFKNMP-------------QFAKAFGCSSNQNMNSKTKCTFF 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	PepO	54..682	CDD:226118	133/713 (19%)
		M13	58..679	CDD:189000	131/706 (19%)
nep-20	NP_001317749.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920