Protein Alignment Nepl18 and nep-26

DIOPT Version :9

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_001022540.1
• Gene: nep-26 / 174593
• WormBaseID: WBGene00014171
• Length: 807
• Species: Caenorhabditis elegans
• Alignment Length: 746
• Identity: 173/746 - (23%)
• Similarity: 280/746 - (37%)
• Gaps: 183/746 - (24%)

  Fly    58 VSPCDDFYTHACGNWHRHNPAQLLGDVMTDNFKLISKGFDRRLQRLLRANDLQSEL-----EKKM 117
            |.|||:||..|||.|...: ..|..|.....::......|:.:|.:.:.||....|     |:..
 Worm   124 VEPCDNFYQFACGGWINQS-VNLKYDSWNTLYETQRTAHDQIVQAMHKINDGSYPLPTNAGERAA 187

  Fly   118 QRFYMSC---NLVHRDDVHYKLALENVIREY-GTLPAL--------------------------- 151
            .:.|..|   :.:.:..:|   ..|..:.|. |.:|.|
 Worm   188 AKMYEQCMDTDTLEQTGLH---LWERFVDELGGWMPELKNGALEQEESFEIELDEDEKKRRRFEI 249

  Fly   152 ---VGAQWNSSDFSWWRTVAQIQHKYGKQ----------IIIGLEIMHDIRNTSVNRVYISQPDF 203
               :.:.:|.|.|..:....::.:...|:          |::..|..|..:..:...:|     .
 Worm   250 EDIILSAFNYSVFPLFWAGVEVNYLNSKEHLITIYEQLPILLAPEKYHYNKELTPEMIY-----G 309

  Fly   204 KTINTRLTNLMEEVRTSMDLQQYFGLSSSVAKHTAEQLTELERTFSSGGSGAATLQESLSLYTVA 268
            |.....:|..:::|...:.....|..:....:.....:..||...:..||  ...:|....|||.
 Worm   310 KMEGPPVTRALQQVGEELSAVLGFDSTDEKVRMMIANMIYLEYQITMAGS--TFYKEKKERYTVV 372

  Fly   269 DLQE--KYSDHLNFTEFLGLILGE--------------ENIPKSLYIYDEEYLDKALLTMRSTPL 317
            .|:|  :.:..:|:..||..::||              :.||....|.::       |....:.:
 Worm   373 MLRELQEIAPAINWHYFLSRLVGENLSHSEPIALKTGTQWIPILSAIVEK-------LKQSRSGV 430

  Fly   318 ATQANYVLWKLLEDFLVDAQPK--DMVKWCTESTKKYFGKLAEHAVYKRYRNPDVESEVHKIWDQ 380
            |...|||.||.:...|..|.||  |.:.|...|.  |.|..::...:...|
 Worm   431 AVLKNYVKWKTIMFHLAYASPKCRDGLLWMAVSL--YSGAASQRKEFCVLR-------------- 479

  Fly   381 IKGIFRQRL--LGDKLDWISNATRTLAI---------EKLERMHLNINSY-DEENFENVYGEVFI 433
            :.|||...|  :..|:|.|.:..:.:..         ||.|.|..:.|.: |.|..|||     |
 Worm   480 LSGIFPLSLPSILRKIDGIDHTEKNVKAVQNIADRIQEKYEEMVRSSNLFSDRETRENV-----I 539

  Fly   434 DRLNYVSNV---------QQLLIAKGIRF-------------------VARINQPADS---VDAT 467
            |::|.::..         ...:..:.:|.                   :.|:..|.|.   ||..
 Worm   540 DKVNNMTKFIGFPDAMRSDYEMEKEAVRLHDTLFWSMVLGSSSVYKERLQRLRLPVDPRSWVDTR 604

  Fly   468 ELLGFTPAYNIQENNITIPVALLQPRYFWGDQYP-EALKYATLGYLLAHEMLHGFDDDGRQYDAS 531
            ..:. .||:|.:.|.:.||...|:..|  .|::. :...||.:|.::.||:.|.||..|:.:..:
 Worm   605 PAIS-VPAHNYERNLVQIPFDSLRLPY--ADEHQLDFANYAGIGTIIGHELTHAFDGQGKLHGPT 666

  Fly   532 GNLAPWWDLKSRYEFEERRKCFQAQYHEYQYGGSKLPESKDQS-------ENIADSGGLKLAYAA 589
            |||..||...|..||:.|.:||..||       :.|.:|.|.:       |||||..|||:||.|
 Worm   667 GNLGVWWSTDSIREFKAREQCFVKQY-------AGLMDSHDMNAAKEGLYENIADQVGLKVAYEA 724

  Fly   590 YELWLGQQSEEVLQRETMEGL-PFNSRQLFFLGYAQLLC--DDVQFLFQPWVSQSDRHAPSKYRV 651
            ::....|.|..      |.|| .::..|||||.|.|..|  ....:..||       |...:.|:
 Worm   725 WKSNGNQNSGR------MPGLEKYSQDQLFFLAYTQGWCALRSKSYKLQP-------HMEERIRM 776

  Fly   652 IGPLSNFQEFPWVFNCSQSAPMDPEYKCAIY 682
            :|.|.|..||...:.||..:.|:|..||:|:
 Worm   777 LGSLQNSPEFASAWKCSSESFMNPPDKCSIW 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	PepO	54..682	CDD:226118	172/744 (23%)
		M13	58..679	CDD:189000	170/741 (23%)
nep-26	NP_001022540.1	PepO	111..807	CDD:226118	172/744 (23%)
		M13	124..805	CDD:189000	171/742 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020