Protein Alignment Nepl18 and nep-13

DIOPT Version :9

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_001342017.1
• Gene: nep-13 / 173672
• WormBaseID: WBGene00018196
• Length: 732
• Species: Caenorhabditis elegans
• Alignment Length: 712
• Identity: 165/712 - (23%)
• Similarity: 280/712 - (39%)
• Gaps: 139/712 - (19%)

  Fly    46 KVAEMKTM-------MKPEVSPCDDFYTHACGNWHRHNPAQLLGDVMTDN------FKLISKGFD 97
            |.||..|:       ....:.||:|||.::||.:..|.    |.|.:..|      .|||.
 Worm    85 KTAECITLSSTLLNWQNTNIDPCEDFYEYSCGRYQEHT----LNDGIRANEKDTIVMKLIR---- 141

  Fly    98 RRLQRLLRANDLQSELEKKMQRFYMSCNLVHR-------DDVHYKLALENVIREYGTLPALVGAQ 155
               |.:|:.....|..|..:...|..|:|.:|       .:|..:...|| ||:.|:.| :....
 Worm   142 ---QFVLKNQSTTSNSENALMLLYEKCSLRYRMENRHQETEVIQREVFEN-IRKIGSWP-IADKN 201

  Fly   156 WNSSDFSWWRTVAQIQHKYGKQIIIGLEIMH----DIRNTSVNRVYISQPDFKTINTRLTNLM-- 214
            ||||.|:.            ..::..:..:|    .:..|.|..:|......|.:..|.|.|.
 Worm   202 WNSSHFNL------------NNMLSNMASIHMLPFGLFETRVIELYPMNTTAKQLVIRPTKLKFS 254

  Fly   215 ----EEVRTSMDLQQYFGLSSSVAKHTAEQLTE---LERTFSS----GGSGAATLQESLSLYTVA 268
                |.||...||....|: :|:.|...|.:.|   |::...:    .....|||.|........
 Worm   255 IPQEELVRAIRDLLSVNGI-TSIMKKVKEDVAESFALDKEIGNIHIDPQPKPATLSELQKAVPDI 318

  Fly   269 DLQEKYSDHLN-------------FTEFLGLILGEENIPKSLYIYDEEYLDKALLTMRSTPLATQ 320
            |.:.....:||             |:....|..|:.|             :.:.:..|:.| ...
 Worm   319 DFERIIKSYLNPKTGNWSSLRTKIFSARFELFFGKNN-------------NLSSIIARTKP-RIL 369

  Fly   321 ANYVLWKLLE----DFLVDAQPKDMVKWCTESTKKYFGKLAEHAVYKRY---RNPDVESEVHKIW 378
            |||:..|.:|    .|..:.:......:|||.......:.:.....:.:   .|..|.||:.::
 Worm   370 ANYLFLKYIEYAYFFFFDNTKVFSDDDFCTEVVTTSLPRASLRVFVRNHFKKENMAVASEIVEV- 433

  Fly   379 DQIKGIFRQRLLGDKLDWISNATRTLAIEKLERMHLNINSYDEENFENVYGEVFIDRLNYVSNVQ 443
              :|..:.:.:  :...|:.|:||..||||:.:|...|...:|........|:|.......|:..
 Worm   434 --VKTAYVEII--NNSTWLHNSTRESAIEKVVKMKKVIGYTEEYERTGALDEMFETLQLSRSDSF 494

  Fly   444 QLLIAKGIRFVARINQPADSVDATELLG-----------FTPAYNIQENNITIPVALLQPRYFWG 497
            .:|:.|..||  :|.|..|.|.:..||.           :.|..|:.  |:.:|. |.:|.:.:
 Worm   495 FVLMTKVNRF--KIEQLMDFVSSDSLLNPIEPLVMANAFYFPTKNLL--NVLVPF-LDKPLFDF- 553

  Fly   498 DQYPEALKYATLGYLLAHEMLHGFDDDGRQYDASGNLAPWWDLKSRYEFEERRKCFQAQYHEYQY 562
             :||..:..|.:|.:||||:.|.||.:|||.|..|....||..:...|::.|.:||..|:..:
 Worm   554 -KYPRYVAMAGVGRVLAHEIGHAFDINGRQTDEIGRTRDWWTREDTEEYDRRSECFAEQFTNF-- 615

  Fly   563 GGSKLPESKDQ-------SENIADSGGLKLAYAAYELWLGQQSEEVLQRETMEGLPFNSRQLFFL 620
               |.|..|.:       :|.|||:.|::.::.|::.....:.:.::|.|..:   |.  :|:|.
 Worm   616 ---KDPSFKGKQNGTEVLAEIIADALGMEASWIAFKKINLTEEQGLIQFEDHD---FG--KLYFQ 672

  Fly   621 GYAQLLCDDVQFLFQPWVSQSDRHAPSKYRVIGPLSNFQEFPWVFNCSQSAPMDPEYKCAIY 682
            ..|...|...:  .:...|....|..:|:|:.|..||.:.|...:.|...:.|:|..:|.::
 Worm   673 VAALDFCAPSR--IEERYSDQLSHPTNKFRINGAFSNSRAFADTYKCPVGSKMNPVQRCDMF 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	PepO	54..682	CDD:226118	161/695 (23%)
		M13	58..679	CDD:189000	160/688 (23%)
nep-13	NP_001342017.1	M13	104..729	CDD:189000	160/688 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920