Protein Alignment Nepl18 and Eef1ece2

DIOPT Version :10

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_808810.1
• Gene: Eef1ece2 / 110599584
• MGIID: 6121518
• Length: 910
• Species: Mus musculus
• Alignment Length: 703
• Identity: 186/703 - (26%)
• Similarity: 310/703 - (44%)
• Gaps: 98/703 - (13%)

  Fly    41 IIVQAKVAEMKTMMKPEVSPCDDFYTHACGNWHRHNPAQLLGDVMTDNFKLISKGFDRRLQRLLR 105
            |.|..|:.|   .:...||||.|||..:||.|.|.||.. .|....:.|..:.......|:.||.
Mouse   245 IRVAGKILE---SLDRGVSPCQDFYQFSCGGWIRRNPLP-NGRSRWNTFNSLWDQNQAILKHLLE 305

  Fly   106 AN--DLQSELEKKMQRFYMSCNLVHRDDVHYKLALENVIREYGTLPALVGAQWNSS----DFSWW 164
            ..  :..||.|:|.:.||:||....|.:......|.::|.:.|        .||.:    :.|:.
Mouse   306 NTTFNSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLIDKIG--------GWNITGPWDEDSFM 362

  Fly   165 RTVAQIQHKYGKQIIIGLEIMHDIRNTSVNRVYISQ-----PDFKTINTRLTNLMEEVRTS---- 220
            ..:..:...|.......:.:..|.::::.|.:.:.|     |.......|..|  |:|.|:
Mouse   363 DVLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTAN--EKVLTAYLDY 425

  Fly   221 -MDLQQYFGLSSSVAKHTAEQLTELERTFSSGGSGAATLQESLSLY---TVADLQEKYSDHLNFT 281
             ::|....|...:..:...:|:.|||...::........::...:|   ::::|| ..:..:::.
Mouse   426 MVELGVLLGGQPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ-ALAPAVDWL 489

  Fly   282 EFLGLILGEENIPKS--LYIYDEEYLDKALLTMRSTPLATQANYVLWKL-------LEDFLVDAQ 337
            |||..:|....:..|  :.:|..|||.:....:..|..:...||::|.|       |:.....||
Mouse   490 EFLSFLLSPLELGDSEPVVVYGTEYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFETAQ 554

  Fly   338 PKDM-----------VKW--CTESTKK----YFGKLAEHAVYKRYRNPDVESEVHKIWDQIKGIF 385
            .|.:           .:|  |..:|..    ..|.|...|.:.|......|..:    ::|:..|
Mouse   555 EKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMI----NEIRSAF 615

  Fly   386 RQRLLGDKLDWISNATRTLAIEKLERMHLNINSYD----EENFENVYGEVFIDRLNYVSNVQQLL 446
             :..||| |.|:...||..|.||.:.::..|...|    .:..::||....:...::..|:..|
Mouse   616 -EETLGD-LVWMDEKTRLAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNL- 677

  Fly   447 IAKGIRFVARINQPADSV---DATELLGFTP----AYNI-QENNITIPVALLQPRYFWGDQYPEA 503
                ..|.|::  .||.:   .:.:....||    ||.: .:|.|..|..:||.. |:...:|:|
Mouse   678 ----YNFSAKV--MADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAP-FYAHNHPKA 735

  Fly   504 LKYATLGYLLAHEMLHGFDDDGRQYDASGNLAPWWDLKSRYEFEERRKCFQAQYHEYQYGGSKLP 568
            |.:..:|.::.||:.|.|||.||:||..|||.|||..:|...|:....|.:.||.:||..|.:|.
Mouse   736 LNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLTAFQNHTACMEEQYSQYQVNGERLN 800

  Fly   569 ESKDQSENIADSGGLKLAYAAYELWLGQQSEEVLQRETMEGLPFNSRQLFFLGYAQLLCDDVQFL 633
            ..:...|||||:||||.||.||:.||.:..||    :.:..:...:.||||:|:||:.|.    :
Mouse   801 GLQTLGENIADNGGLKAAYNAYKAWLRKHGEE----QPLPAVGLTNHQLFFVGFAQVWCS----V 857

  Fly   634 FQPWVSQ----SDRHAPSKYRVIGPLSNFQEFPWVFNCSQSAPMDPEYKCAIY 682
            ..|..|.    :|.|:|:::||:|.|||.::|...|.|...:||:|...|.::
Mouse   858 RTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 910

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	M13	58..679	CDD:341056	181/681 (27%)
Eef1ece2	NP_808810.1	UbiG	46..>128	CDD:441829
		M13	259..908	CDD:341056	181/682 (27%)