Protein Alignment Nepl18 and phex

DIOPT Version :9

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: XP_004911718.1
• Gene: phex / 100496470
• XenbaseID: XB-GENE-1012247
• Length: 750
• Species: Xenopus tropicalis
• Alignment Length: 715
• Identity: 185/715 - (25%)
• Similarity: 317/715 - (44%)
• Gaps: 126/715 - (17%)

  Fly    48 AEMKTMMKPEVSPCDDFYTHACGNWHRHNPAQLLGDVMTDN--FKLISKGFDRRLQRLLR---AN 107
            |.:::.|...|.|||||:.:|||.|...||   :.|.|::.  :..:....|.:|:.||.   :.
 Frog    65 ASIRSKMNLSVDPCDDFFQYACGGWIEENP---IPDDMSNYGIYPWLRTNVDLKLKALLEKPISK 126

  Fly   108 DLQSELEKKMQRFYMSC---NLVHRDDVH--YKLALENVIREYGTLPALVGA--QWNSSDFSWWR 165
            ...||..:|::.||:||   ..:..||:.  .|:..:..:| :..|.:.:|:  :|:...||:.:
 Frog   127 RRDSEAIQKVKTFYISCMNETQIEEDDIKPILKILKQPSLR-WPVLESNIGSDGKWSERKFSFLQ 190

  Fly   166 TVAQIQHKYGKQIIIGLEIMHDIRNTSVNRVYISQPDFKTINTRLTNLMEEVRTSMDLQQYFGLS 230
            |||.::..|...:.:              |||::..| |..|..:..|.:...:.:..:.|.. :
 Frog   191 TVADLRRLYSTSVFL--------------RVYVAIDD-KVSNNFILKLDQASLSLLSHEDYLD-N 239

  Fly   231 SSVAKHTAEQLTE----LERTFSSGGSGAAT-------LQESLSLYTVAD---LQEKYSDHLNFT 281
            |::||...:.|.|    :.....:..:.|.|       |:..|:..||..   ..|...:.:|.:
 Frog   240 STIAKKYRDALLEFMVDVAVLLGANKTRAETDMKALIELETKLAQITVPQENRTSEMMYNKMNIS 304

  Fly   282 EFLGLI--------------------LGEENIPKSLYIYDEEYLDKALLTMRSTPLATQANYVLW 326
            |...:|                    |...::.:::.:...::.......:.|....|.|||::|
 Frog   305 ELSAMIPQFDWLSYLKNIIDFNIYPELKNIDLSENVIVRVPQHFKDLFNIIESEEKRTLANYLIW 369

  Fly   327 KLLEDFLVDAQPKDMV-----------------KW--C---TESTKKY-FGKLAEHAVYKRYRNP 368
            :|:...:.:...:...                 :|  |   .|::..| .|||...|.::.
 Frog   370 RLVYSRIPNLSRRFQYRQLEFARILLGTNSLAGRWDRCVNYVENSIPYPVGKLFVDAHFQE---- 430

  Fly   369 DVESEVHKIWDQIKGIFRQRLLGDKLDWISNATRTLAIEKLERMHLNINSYDEENFENVYGEVFI 433
            |.:..:.::.|.|:..|.. :|..:.||:...|:..|.:|...:...: .|.|..|.:.|....|
 Frog   431 DKKDMMEELVDGIRWAFID-MLEKENDWMDAETKIKAKQKAVTVMAKV-GYPEFLFNDTYLNEDI 493

  Fly   434 DRL-----NYVSNVQQLL--IAKGIRFVARINQPADS--VDATELLGFTPAYNIQENNITIPVAL 489
            ..|     :|..||.|.|  |::...:..|.|.|...  .:.|.:..|   |:...|.|..|...
 Frog   494 KMLKFSESDYFGNVLQTLHFISQSDFYWLRRNVPKKEWFTNPTTVNAF---YSASTNQIRFPAGE 555

  Fly   490 LQPRYFWGDQYPEALKYATLGYLLAHEMLHGFDDDGRQYDASGNLAPWWDLKSRYEFEERRKCFQ 554
            ||..:|||.|||.:|.|..:|.::.||..||||::||:||..|||..||..:|...|:.:..|..
 Frog   556 LQKPFFWGVQYPRSLSYGAIGVIVGHEFTHGFDNNGRKYDKEGNLFSWWTSESEERFKNKTLCMV 620

  Fly   555 AQYHEYQY--GGSKLPESKDQSENIADSGGLKLAYAAYELW---LGQQSEEVLQRETMEGLPFNS 614
            .||:.|.:  .|..:...|..||||||:||::.::.||..|   |.:..||:|    :.||..|:
 Frog   621 EQYNNYYWKQAGLHVKGMKTLSENIADNGGIRESFRAYRKWIEDLRKGKEEML----LPGLDLNN 681

  Fly   615 RQLFFLGYAQLLCDDVQFLFQPWVSQSDR-----HAPSKYRVIGPLSNFQEFPWVFNCSQSAPMD 674
            .||||:.||.:.|:..:.     .|..|:     |:|.::||||.:|||:||...|:|.:.:.|:
 Frog   682 NQLFFISYAHVRCNSFRI-----ESARDQIMNGVHSPPQFRVIGAMSNFEEFHKAFSCPKDSKMN 741

  Fly   675  674
             Frog   742  741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	PepO	54..682	CDD:226118	184/709 (26%)
		M13	58..679	CDD:189000	183/705 (26%)
phex	XP_004911718.1	M13	75..741	CDD:341056	182/703 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010