Protein Alignment Nepl18 and ece1

DIOPT Version :9

• Sequence 1: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: XP_031762312.1
• Gene: ece1 / 100485607
• XenbaseID: XB-GENE-1014218
• Length: 782
• Species: Xenopus tropicalis
• Alignment Length: 702
• Identity: 188/702 - (26%)
• Similarity: 299/702 - (42%)
• Gaps: 131/702 - (18%)

  Fly    60 PCDDFYTHACGNWHRHNPAQLLGDVMTDNFKLISKGFDRRLQRLLRANDLQ--SELEKKMQRFYM 122
            ||.|||.::||.|.:.||.. .|......|..:.:.....::.||..:.::  |..|:|.||::.
 Frog   133 PCQDFYQYSCGGWIKGNPVP-DGHSRWGTFNELWEHNQATMKHLLENSTIETNSTAERKAQRYFQ 196

  Fly   123 SC-NLVHRDDVHYKLALENVIREYGTLPALVGAQWNSSDFSWWRTVAQIQHKYGKQIIIGLEIMH 186
            :| |....:::..| .|:::|::.|.. |:.| .|:..:|.  .|:..:...|.......:.:..
 Frog   197 ACMNETKIEELGAK-PLQDLIQKLGGW-AITG-PWDRDNFQ--ETLQLVTAHYRTSPFFSVFVSA 256

  Fly   187 DIRNTSVNRVYISQPDF----------KTINTRLTNLMEEVRTS-MDLQQYFG-LSSSVAKHTAE 239
            |.:|::.|.:.|.|...          ||.|       |:|.|. ::.....| |.......|.|
 Frog   257 DSKNSNSNVIQIDQSGLGLPSREFYLNKTEN-------EKVLTGYLNFMIQLGVLLGGAENSTRE 314

  Fly   240 QLTELERTFSSGGSGAATLQESLSLYTVADLQEKYSDH------------------LNFTEFLGL 286
            |:.|:             |....:|..:...|||..|.                  :::..||..
 Frog   315 QMQEI-------------LDFETTLANITIPQEKRRDEEQIYHKMAAGELKDLVPAVDWMPFLQT 366

  Fly   287 ILGEENIPKS--LYIYDEEYLDKALLTMRSTPLATQANYVLWKL-------LEDFLVDAQPKDMV 342
            :.....|.:|  :.:|.:|||......:.||......||::|.|       |:....||:.|.|.
 Frog   367 VFYPVAINESEPVVVYAKEYLVAVSGLINSTDKRILNNYMMWNLVRKASSFLDQRFQDAEEKLME 431

  Fly   343 -------------KWCTESTKKYFGKLAEHAVYKRYRNPDVESEVHKIWDQIKGIFRQRLLGDKL 394
                         |:|...|....|........|.....:.:.:..|:..:||..|.:.|  ..|
 Frog   432 VMYGTKKTCLPRWKFCISDTDNNLGFALGAMFVKATFAENSKLQALKMIKEIKAAFEENL--STL 494

  Fly   395 DWISNATRTLAIEKLERMHLNINSY-----DEENFENVYGEVFIDRLNYVSNVQQLLIAKGIRFV 454
            .|:.:.||..|.||.|.:: ::..|     |.:..:.|:.:..:....|..|        |:||.
 Frog   495 TWMDDETRRAAREKAEAIY-DMIGYPNFIMDPKELDKVFNDYNVTSDFYFEN--------GMRFY 550

  Fly   455 ---ARIN----QPADSVDATELLGFTPA-----YNIQENNITIPVALLQPRYFWGDQYPEALKYA 507
               ||:.    :.|.|.|...:   ||.     |:..:|.|..|..:||.. |:....|.||.:.
 Frog   551 NFSARVTADQLRKAPSKDQWSM---TPPTVNAYYSPTKNEIVFPAGILQAP-FYTSSSPTALNFG 611

  Fly   508 TLGYLLAHEMLHGFDDDGRQYDASGNLAPWWDLKSRYEFEERRKCFQAQYHEYQYGGSKLPESKD 572
            .:|.::.||:.|.|||.||:||..|||.|||...|...|:::.:|...||..|...|..:...:.
 Frog   612 GIGVVMGHELTHAFDDQGREYDKDGNLRPWWKNASVEAFKKQTECITEQYGNYTVNGEPVNGRQT 676

  Fly   573 QSENIADSGGLKLAYAAYELWLGQQSEEVLQRETMEGLPFNSRQLFFLGYAQLLCDDVQFLFQPW 637
            ..|||||:||||.||.||:.|:.:...|.|    :..|..::.||||:|:||:.| .|:
 Frog   677 LGENIADNGGLKAAYRAYKNWVRKNGAEQL----LPSLGLSNDQLFFVGFAQVWC-SVR------ 730

  Fly   638 VSQS-------DRHAPSKYRVIGPLSNFQEFPWVFNCSQSAPMDPEYKCAIY 682
            .|:|       |.|:||::||||.:||.|||...|.|...:||:|..||.::
 Frog   731 TSESSHEGLITDPHSPSRFRVIGSVSNSQEFAEHFRCPPGSPMNPRNKCEVW 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl18	NP_651643.1	PepO	54..682	CDD:226118	188/700 (27%)
		M13	58..679	CDD:189000	186/697 (27%)
ece1	XP_031762312.1	M13	131..780	CDD:341056	187/698 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010