Protein Alignment Nepl17 and Ecel1

DIOPT Version :10

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: XP_063123735.1
• Gene: Ecel1 / 60417
• RGDID: 61806
• Length: 792
• Species: Rattus norvegicus
• Alignment Length: 708
• Identity: 165/708 - (23%)
• Similarity: 279/708 - (39%)
• Gaps: 141/708 - (19%)

  Fly    42 AKSAEMCSF-MDTSVSPCDDFYGYACG-------------NYATINAATSQKDTNIRQLMFANYL 92
            |::|...|. :|.|:.||.|||.:|||             .|.||.|...|.:
  Rat   107 ARAARFLSANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNE------------ 159

  Fly    93 RRVRQVLNEPRISTDRPMEVRVKYFYESCLDTAALRTKQRSHLLSVLREFGGMPAVEGKSWDYVG 157
            .|:|::|..|........:.:|:.|:.||||...:.......:|.|:.:.||        ||..|
  Rat   160 ERLRRLLARPTGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGG--------WDLGG 216

  Fly   158 ---------FDAIEMMAQLLRRYGKLTLLGVYVVPDHFNSQIKRLQLGQ--------RLDLAESD 205
                     :|...::.:....|....|..:.|..|..||....:::.|        .|.||:.:
  Rat   217 AADRPGAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDE 281

  Fly   206 EFASLWKKYALKM-RLRNLLGLSEELARKTAEEIIELELEL---SRSAFDHRMNRDPRLMRHLTM 266
            |...:...|.:.| ||..|||  .:...:.|:||::||..|   |.|.:|. :.||
  Rat   282 ESEKVLAAYKVFMERLLRLLG--ADAVEQKAQEILQLEQRLANISVSEYDD-LRRD--------- 334

  Fly   267 LSNMSDAY-----GPILNVTRFVT-SWLGSEYNLPVFES-----------VPSYLFQVKKILLST 314
               :|..|     |.:..:|..:. .||..:    :|:.           ...|:.||.:::.||
  Rat   335 ---VSSVYNKVTLGQLQKITPHLQWKWLLDQ----IFQEDFSEEEEVVLLATDYMQQVSQLIRST 392

  Fly   315 PNHVVANYM-------LSSLLTD----------FEITANEEQQKV--ICHERITELFPDVVDHMV 360
            |..::.||:       ||..|:.          .|:..|::.|::  :|..:....|...:..:.
  Rat   393 PRRILHNYLVWRVVVVLSEHLSPPFREALHELAKEMEGNDKPQELARVCLGQANRHFGMALGALF 457

  Fly   361 YHSLEQQNPYIANEMRSLWVELKSSFREMLSSPDIEWLEKQTREELLEKLNGMSFEIA------G 419
            .|  |..:.....:::.|..::|....:.|.  :::|::.||:.....||..|...:.      .
  Rat   458 VH--EHFSAASKAKVQQLVEDIKYILGQRLE--ELDWMDAQTKAAARAKLQYMMVMVGYPDFLLK 518

  Fly   420 GQAVNFEEQFGDLVVSSADYYGNIQRLLEVKARILRTDLLRE-SSSVYYYHGVTATPIYETETNL 483
            .:||:.|.:|   .|....|:.||...:....::....:.:| ..|.:..........|....|.
  Rat   519 PEAVDKEYEF---EVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYYLPNKNQ 580

  Fly   484 VVLPVSYMQHRYLWDDIYPAALKYGTLGFTMAHEMAHGFDDLNRLYDSRGNLNDNWSTQTKVGFE 548
            :|.|...:|.. |:|..:|.:|.||.:|..:.||:.||:||....||..|||...|:..:...|.
  Rat   581 MVFPAGILQPT-LYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHWWTEASYSRFL 644

  Fly   549 LVKNCLADQFSGMLYGNLRLRRLKSQAESIADNVGIRIAQSAYWKWLDQVEMEETESLPHMTQSP 613
            ....|:...:......|.|:....:..|:|||..|:::|..||.||:.:...|  ..|..:..:.
  Rat   645 HKAECIVRLYDNFTVYNQRVNGKHTLGENIADMGGLKLAYYAYQKWVREHGPE--HPLHRLKYTH 707

  Fly   614 EQLFFLSAAQFMC-----SDIYPERRANFVRNNFHPPYEARVFAMMINSPAFAEAFQC 666
            .||||::.||..|     ..||.:     |..:.|.|...|...:    |::|....|
  Rat   708 NQLFFIAFAQNWCIKRRSQSIYLQ-----VLTDKHAPEHYRYACL----PSWAVPSLC 756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	M13	55..678	CDD:341056	160/694 (23%)
Ecel1	XP_063123735.1	None