Protein Alignment Nepl17 and Nepl18

DIOPT Version :10

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Alignment Length: 686
• Identity: 216/686 - (31%)
• Similarity: 350/686 - (51%)
• Gaps: 29/686 - (4%)

  Fly    10 LIFVTLAVGSLAIQGGVF-KELTTPLGQQIMRIAKSAEMCSFMDTSVSPCDDFYGYACGNYATIN 73
            |:.:..|:...:..|..| .:||:...::|:..||.|||.:.|...||||||||.:||||:...|
  Fly    12 LVAIVPAMAKPSDAGDPFADDLTSDYAKKIIVQAKVAEMKTMMKPEVSPCDDFYTHACGNWHRHN 76

  Fly    74 AATSQKD--TNIRQLMFANYLRRVRQVLNEPRISTDRPMEVRVKYFYESCLDTAALRTKQRSHLL 136
            .|....|  |:..:|:...:.||::::|....:.::  :|.:::.||.||..........:..|.
  Fly    77 PAQLLGDVMTDNFKLISKGFDRRLQRLLRANDLQSE--LEKKMQRFYMSCNLVHRDDVHYKLALE 139

  Fly   137 SVLREFGGMPAVEGKSWDYVGFDAIEMMAQLLRRYGKLTLLGVYVVPDHFNSQIKRLQLGQRLDL 201
            :|:||:|.:||:.|..|:...|.....:||:..:|||..::|:.::.|..|:.:.|:.:.|....
  Fly   140 NVIREYGTLPALVGAQWNSSDFSWWRTVAQIQHKYGKQIIIGLEIMHDIRNTSVNRVYISQPDFK 204

  Fly   202 AESDEFASLWKKYALKMRLRNLLGLSEELARKTAEEIIELELELSRSAFDHRMNRDPRLMRHLTM 266
            ..:....:|.::....|.|:...|||..:|:.|||::.|||...|...     :....|...|::
  Fly   205 TINTRLTNLMEEVRTSMDLQQYFGLSSSVAKHTAEQLTELERTFSSGG-----SGAATLQESLSL 264

  Fly   267 --LSNMSDAYGPILNVTRFVTSWLGSEYNLP----VFESVPSYLFQVKKILLSTPNHVVANYMLS 325
              ::::.:.|...||.|.|:...||.| |:|    :::.  .||.:....:.|||....|||:|.
  Fly   265 YTVADLQEKYSDHLNFTEFLGLILGEE-NIPKSLYIYDE--EYLDKALLTMRSTPLATQANYVLW 326

  Fly   326 SLLTDFEITANEEQQKVICHERITELFPDVVDHMVYHSLEQQNPYIANEMRSLWVELKSSFREML 390
            .||.||.:.|..:.....|.|...:.|..:.:|.||.  ..:||.:.:|:..:|.::|..||:.|
  Fly   327 KLLEDFLVDAQPKDMVKWCTESTKKYFGKLAEHAVYK--RYRNPDVESEVHKIWDQIKGIFRQRL 389

  Fly   391 SSPDIEWLEKQTREELLEKLNGMSFEIAGGQAVNFEEQFGDLVVSSADYYGNIQRLLEVKARILR 455
            ....::|:...||...:|||..|...|......|||..:|::.:...:|..|:|:||..|.....
  Fly   390 LGDKLDWISNATRTLAIEKLERMHLNINSYDEENFENVYGEVFIDRLNYVSNVQQLLIAKGIRFV 454

  Fly   456 TDLLRESSSVYYYHGVTATPIYETETNLVVLPVSYMQHRYLWDDIYPAALKYGTLGFTMAHEMAH 520
            ..:.:.:.||.....:..||.|..:.|.:.:||:.:|.||.|.|.||.||||.|||:.:||||.|
  Fly   455 ARINQPADSVDATELLGFTPAYNIQENNITIPVALLQPRYFWGDQYPEALKYATLGYLLAHEMLH 519

  Fly   521 GFDDLNRLYDSRGNLNDNWSTQTKVGFELVKNCLADQFSGMLYGNLRLRRLKSQAESIADNVGIR 585
            ||||..|.||:.|||...|..:::..||..:.|...|:....||..:|...|.|:|:|||:.|::
  Fly   520 GFDDDGRQYDASGNLAPWWDLKSRYEFEERRKCFQAQYHEYQYGGSKLPESKDQSENIADSGGLK 584

  Fly   586 IAQSAYWKWLDQ-----VEMEETESLPHMTQSPEQLFFLSAAQFMCSDIYPERRANFVRNNFHPP 645
            :|.:||..||.|     ::.|..|.||.   :..|||||..||.:|.|:....:....:::.|.|
  Fly   585 LAYAAYELWLGQQSEEVLQRETMEGLPF---NSRQLFFLGYAQLLCDDVQFLFQPWVSQSDRHAP 646

  Fly   646 YEARVFAMMINSPAFAEAFQCSNSSKMNPPNKCLMY 681
            .:.||...:.|...|...|.||.|:.|:|..||.:|
  Fly   647 SKYRVIGPLSNFQEFPWVFNCSQSAPMDPEYKCAIY 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	M13	55..678	CDD:341056	200/635 (31%)
Nepl18	NP_651643.1	M13	58..679	CDD:341056	200/635 (31%)