Protein Alignment Nepl17 and Nepl16

DIOPT Version :10

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Alignment Length: 758
• Identity: 145/758 - (19%)
• Similarity: 275/758 - (36%)
• Gaps: 203/758 - (26%)

  Fly     7 SACLIFVTLAVGSLAIQGGVFKELTTPL-------GQQIMRIAKSAEMCS-------------FM 51
            ||.|:..||.|.|..:  .:.....:||       |.:......:...||             .:
  Fly   109 SATLLVTTLLVASPIL--FLISTAPSPLPRDCYMDGDRCSPAVSAPPECSDPICEAVASSIQARL 171

  Fly    52 DTSVSPCDDFYGYACGNYA-------TINAATSQKDTNIRQL-MFANYLRRVR-QVLNEPRISTD 107
            :.:..||.:|..::|....       .|....|||..:.:.| :|.|.:.... .:|:.
  Fly   172 NWNKDPCTEFKKFSCWRNTPNKNITNLIEMGNSQKSVDSQMLYLFQNKIMNGSFGILHN------ 230

  Fly   108 RPMEVRVKYFYESCLDTAALRTKQRSHLLSVLREFGGMPAVEGKSWDYVGFDAIEMMAQLLRRYG 172
                     .:||||.    :|...:.:..:....||...|..     ||..:|..:...:...|
  Fly   231 ---------LFESCLQ----QTTNSTVMHRIFDSLGGYLPVGS-----VGPSSIAPLIAKIYDLG 277

  Fly   173 KLTLLGVYVVPDHFNSQIKRLQLGQRLDL-----AESDEFASLWKKY------ALKMRLR----- 221
            ...|:.:|          ..|..|:|..:     ..|.....|.:|.      |...|:|
  Fly   278 PSPLVDLY----------HDLSYGRRPHILLIISGPSTSSTILERKIRWMSPKAPPSRIRQGVPK 332

  Fly   222 -------NLLGLSEELARKTAE---------EIIELELELSRSAF-DHRMNRDPRLMRHLTMLSN 269
                   |.|......|::.:|         ::.:|::|.||..| |..:         |..:|:
  Fly   333 LLADLIENFLPYFVSYAQRVSEKDTIFEFIKDLNKLQVEHSRRGFWDSTV---------LYNVSS 388

  Fly   270 MSDAYGPILNVTRFV-TSWLGSEYNLPVFESVPSYLFQVKKILLSTPNHVVANYMLSSLLTDFEI 333
            :.|.| |:||.|..: .:|.|     |:......||..::..|...|..|..|.:|  ||:..:|
  Fly   389 LQDLY-PVLNWTLLIPQNWSG-----PIVVRNSDYLKALEYFLTKYPTRVAHNSLL--LLSALQI 445

  Fly   334 TANEEQQKVICHERITELFPDVVD--HMVYHSLEQQNPYIANEMRSLWVELKSSFREMLSSPDIE 396
            ...:.....:|........|::..  ::..||.|.    :.:..:...:..||....:..:|.::
  Fly   446 LPRDYPSPEVCTRSTMWALPELSSSLYIAQHSSED----LKDTTKRAEIIFKSLKAHLKRAPSLK 506

  Fly   397 W----------LEKQTRE------ELLEKLNGMSFEIAGGQAVNFEEQFGDLVVSSADYYGNIQR 445
            .          ::.||.|      :||:.|          |.:|         ::|..::.||
  Fly   507 GAALVKLSALKIQSQTWEGFSNTTDLLKSL----------QPLN---------ITSECWFQNI-- 550

  Fly   446 LLEV--KARILRTDL-LRESSSVYYYHGVTATPIYETETNLVVLPVSYMQHRYLWDDIYPAALKY 507
             ||:  |.::...|: |...|...:.:.:.:|..|:|.::.:|:|:|.:...| ::.:.|..|.|
  Fly   551 -LEIYKKNKLEPNDISLNGGSHDAWAYPIVSTIFYDTLSHSIVVPLSVILIPY-FNAVLPPYLHY 613

  Fly   508 GTLGFTMAHEMAHGFDDLNRLYDSRGNLNDNWSTQTKVGFELVKNCLADQFSGMLYGNLRLRRLK 572
            .::|.::|.|:....                    ||...|....|:....:  ::.|.
  Fly   614 ASVGVSIAKEILRSI--------------------TKSFDEKAMRCVPHSVN--IFSNY------ 650

  Fly   573 SQAESIADNVGIRIAQSAYWKWLDQV-EMEETESLPHMTQSPEQLFFLSAAQFMCSDIYPERRAN 636
            |:.:.:..:.|::|   :|...|... .::....||.:..:|.|:|||.:||.:|::      :|
  Fly   651 SRMDILIHSGGMQI---SYHSMLSLTGPIKGMARLPGLNLTPTQIFFLVSAQELCAE------SN 706

  Fly   637 FVRNNFHPPYEARVFAMMINSPAFA-EAFQCSNSSKMNPPNKC 678
            ::..:.:.|....:...::.....| |.|:|.:.|.:|....|
  Fly   707 YLGIDTNAPEFDNILGWLVAQGGSATEVFKCPSGSMINVQKTC 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	M13	55..678	CDD:341056	132/688 (19%)
Nepl16	NP_001097912.1	GluZincin	176..750	CDD:472708	133/689 (19%)