Protein Alignment Nepl17 and Nep4

DIOPT Version :10

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Alignment Length: 856
• Identity: 201/856 - (23%)
• Similarity: 335/856 - (39%)
• Gaps: 229/856 - (26%)

  Fly     6 ASACLIFVTLAVGSLAIQGGVFKELTTPLGQQIMRIAKSAEMCSFMDTSVSPCDDFYGYACGNY- 69
            |||.:...|.|:.|...:.|.         ::.:|:.::..|..:||..|.||.|||.|||||:
  Fly   234 ASAEISEATAALQSFWNEEGT---------REGIRMTQAKTMKRYMDNKVDPCVDFYKYACGNWE 289

  Fly    70 ---------------------------------ATINAATSQKDTNIRQLMF------------- 88
                                             ..:::|...:.:.:|..:|
  Fly   290 RLHPIPKDKAGFDTFEMLRESLDLVLRNLLEKNTPVHSAAELRKSPVRNTLFKLNEQGEGEGEAD 354

  Fly    89 ------ANYLRR----VRQVLNE--------------------PR-------------------- 103
                  |..|||    .||:||.                    ||
  Fly   355 QAAELTAERLRRHIVSKRQLLNRVLVRYKRYTNGTKRKRLIETPRERTKEEEAAPPVVLPKDKTK 419

  Fly   104 ----------ISTD-----RPMEVRVKYFYESCLDTAALRTKQRSHLLSVLREFGGMPAVEGKSW 153
                      :.||     :..:::.|..|.||:::|.|..:....|.:::||.||.|.:|.: |
  Fly   420 DKSDNEEQLHVPTDFLKPHQDAQLKAKNLYRSCVNSAVLAKRGLEPLHTLIRELGGWPVLESQ-W 483

  Fly   154 DYVGFDAIEMMAQLLRRYGKLTLLGVYVVPDHFNSQIKRLQLGQR-LDLAESDEF-----ASLWK 212
            ....|: .:::|..||||....|:..:|..|..||:...:|..|. |.|...:.|     |...:
  Fly   484 SESNFN-WQVLAATLRRYNNDILIVQWVGADIKNSEENIVQFDQTGLGLPTREYFLQPSNAKYLQ 547

  Fly   213 KYALKM-RLRNLLGLSEELARKTAEEIIELELELS--RSAFDHRMNRDPRLMRHLTMLSNMSDAY 274
            .|...| .:.:.:|.|:..|::.|.|::..|.:|:  .:..:.|:| ..:|.:.:|:  :...|.
  Fly   548 AYQRYMAEVMHKMGASKADAQRVASELVAFETQLAGITAPAEQRLN-VTKLYKRMTL--DQLQAV 609

  Fly   275 GPILNVTRFVTSW-----LGSEYNLPVFESVPSYLFQVKKILLSTPNHVVANYMLSSLLTDFEIT 334
            .|.:....::.|.     ||:|   .|......|:.::..:|..|....|:|||:
  Fly   610 VPEIKWRAYLQSLQDREVLGTE---EVVIYAVEYMSKLVTLLDETDPRTVSNYMM---------- 661

  Fly   335 ANEEQQKVICH--ERITELFPDVVDHMVYHSL--------------EQQNPYIANEMRSLWV--- 380
                 .:.:.|  ..:.:.|.| :....||:|              .|.|..:...:.|::|
  Fly   662 -----WRFVRHRINNVDDRFDD-IKQSFYHALFGREESPQRWKVCIAQVNTNMGMAVGSMFVSRY 720

  Fly   381 --------------ELKSSFREMLSSPDIEWLEKQTREELLEKLNGMSFEIAGGQAV----NFEE 427
                          :|:.:||::|.:.|  ||:..|::...||:|.||.:|.....:    ....
  Fly   721 FDNNSKRDTLRMTHDLQQAFRDILKTTD--WLDDTTKQLAEEKVNAMSLKIGYPDFILNPSELNS 783

  Fly   428 QFGDLVVSSADYYGNIQRLLEVKARILRTDLLRESSSVYYYHGVTATPI----YETETNLVVLPV 488
            ::..:.:....|:.|   .|.|.....:|:..:....|...:..||..|    |....|.::.|.
  Fly   784 KYAGIEIYPEKYFEN---TLNVLLHTAKTEQAKLHERVNKTNWQTAPAIVNAYYSRNKNQIMFPA 845

  Fly   489 SYMQ----HRYLWDDIYPAALKYGTLGFTMAHEMAHGFDDLNRLYDSRGNLNDNWSTQTKVGFEL 549
            ..:|    ||:     :|.:|.:|.:|..:.||:.|||||..||:|..||::..|:..:..||:.
  Fly   846 GILQPPFYHRH-----FPKSLNFGGIGVVIGHELTHGFDDKGRLFDRNGNIHKWWTDSSIRGFDE 905

  Fly   550 VKNCLADQFSG--------MLYGNLRLRRLKSQAESIADNVGIRIAQSAYWKWLDQVEME-ETES 605
            ...|:..|:|.        :|.|.      .:|.|:||||.|:|.|..||.:||.:...| ..|.
  Fly   906 RARCIIAQYSNYTVEEVGIVLNGE------STQGENIADNGGLRQAFHAYQRWLKEHPSEVSDEI 964

  Fly   606 LPHMTQSPEQLFFLSAAQFMCSDIYPERRANFVRNNFHPPYEARVFAMMINSPAFAEAFQCSNSS 670
            ||.:..:..|||||:..|..|..:.||...|.:....|.|...||...:.||..||..|.|...|
  Fly   965 LPGLNMTGPQLFFLNFGQVWCGAMRPEAIRNKLNTAIHSPGRFRVIGTLSNSVDFAREFNCPLGS 1029

  Fly   671 KMNPPNKCLMY 681
            .|||..||.::
  Fly  1030 PMNPQKKCSVW 1040

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	M13	55..678	CDD:341056	188/802 (23%)
Nep4	NP_650904.3	M13	274..1038	CDD:341056	189/803 (24%)