Protein Alignment Nepl17 and Nepl10

DIOPT Version :9

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 716
• Identity: 139/716 - (19%)
• Similarity: 271/716 - (37%)
• Gaps: 193/716 - (26%)

  Fly    39 MRIAKSAEMCSFMDTSVSPCDDFYGYACGNYATINAATSQKDTNIRQL--MFAN-YLRRVRQVLN 100
            :.:|.|.::.:.::.:.|||.:|:.:|||.:    ::.|:...|..::  .||. .:..:...|.
  Fly    24 INVATSNDIHNNLNRTTSPCTNFWNFACGRF----SSASKYVDNFERVEDQFATAMVEFMESHLG 84

  Fly   101 E-----PRISTDRPMEVRVKYFYESCLDTAALRTKQRSHLLSVLREFGGMPAVEGKSWDYVGFDA 160
            |     ||:..      :::.:|::|.:..              |:..|.|..|
  Fly    85 ENDTLAPRLIK------QMRQYYKACKEDT--------------RKLHGNPRPE----------- 118

  Fly   161 IEMMAQLLRRYGKLTLLGVYVVPDHFNSQIKRLQLGQRLDLAESDEFASLWKKYALKMRLRNLLG 225
             |::.|.:....|..:.|           :..:.:.:|:|:|.:|..     ::.:::|
  Fly   119 -ELVNQWILHPKKFLVYG-----------LNGVFIDERVDVAANDSM-----RWVIQLR------ 160

  Fly   226 LSEELARKTAEEIIELELELSRSAFDHRMNRDPRLMRHLTMLSNMSDAYG---PILNVTRFVTSW 287
            :.:...|.:...:::| :.|...|: :.|.    :::.:..:..:.|.|.   |:      |.:|
  Fly   161 MPDPADRYSDRRVLQL-MRLYEEAW-YSMG----VVKLVEKMHQLQDKYRAEYPV------VYTW 213

  Fly   288 LGSEYNLPVFESVPSYLFQVKKILLSTPNHVVANYMLSSLLTDFEIT----------ANEEQQKV 342
            ..||....:  .:|...|    |.|...||....|.|:..::|.|..          |:|.:...
  Fly   214 SFSELRQEI--PIPHSFF----IELLGVNHTEELYHLTFEVSDVEYLRECFRCLRDFASEPKDTY 272

  Fly   343 I--------------------CHERITELFP----DVVDHMVYHSLEQQNPYIANEMRSLWVELK 383
            |                    |...:....|    .:.|..:|.:.|:.    .:::..:...||
  Fly   273 IRARQYVLVEESEPRERNPRSCIHHMRAYLPLGMNYIYDRFIYQNREED----TSKVLEILSTLK 333

  Fly   384 SSFREMLSSPDIEWLEKQTREELLEKLNGMSFEIAGGQAVNFEEQ---------FGDLVVSSADY 439
            ::|.:.|.:..::....|. ..:..||.|:..:|.     |..|:         :|....|:.::
  Fly   334 AAFGQYLDANRLQLTPNQL-AYVRAKLEGIQIKIG-----NLPEEKSPEFYNNHYGSANFSATNF 392

  Fly   440 YGNIQRLLEVKARILRTDLLRESSSV---YYY-----HGVTATPIYETETNLVVLPVSYMQHRYL 496
            ..|:.....::.|:....||..:|.|   :||     .....:|.||.|.|.:.:|:.::|.. |
  Fly   393 LANLLEAFALRTRLQNAGLLARNSRVDLRHYYVNDNVRKARTSPFYENERNTITVPMEFLQWP-L 456

  Fly   497 WDDIYPAALKYGTLGFTMAHEMAHGFDDLNRLYDSRGNLNDNWSTQTKVGFELVKN--------C 553
            :|.......::..||..:.|||.|.|:....|:|:.||       ::.||.|:.::        |
  Fly   457 FDHREHTIFQHSLLGAVLGHEMNHAFEQEGILFDAAGN-------ESPVGLEIRESKPFRDAIKC 514

  Fly   554 LADQFSGMLYGNLRLRRLKSQAESIADNVGIRIAQSAYWKWLDQVEMEETESLPHMTQ---SPEQ 615
            ..:|            ...|..|.:||..|:::|..|::....  :..:.|..|:..:   :..|
  Fly   515 AEEQ------------PFVSLKERLADLNGLQLAYDAFFGLAH--DSRQFEYRPYAFEQEFTAPQ 565

  Fly   616 LFFLSAAQFMCSDIYPERRANFVRNNFHPPYEARVFAMMINSPAFAEAFQCSNSSKMNPPNKCLM 680
            ||.||.|||.|..:.|...        |...:.||...:.|...||..|.|..|    |.:.|.|
  Fly   566 LFHLSYAQFFCGSLPPVIA--------HDRDDERVNVSVGNLRQFAYDFNCETS----PSSVCEM 618

  Fly   681 Y 681
            :
  Fly   619 W 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	PepO	49..672	CDD:226118	134/695 (19%)
		M13	55..678	CDD:189000	135/695 (19%)
Nepl10	NP_610787.1	GluZincin	41..608	CDD:301352	132/682 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920