Protein Alignment Nepl17 and Nepl6

DIOPT Version :10

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 752
• Identity: 178/752 - (23%)
• Similarity: 294/752 - (39%)
• Gaps: 179/752 - (23%)

  Fly     8 ACLIFVTLAVGSLAIQGGVFKELTTPLGQQIMRIAKSAEM---CSFMDTSVSPCDDFYGYACGNY 69
            |||..|.:.              ..|..|.:.....|..|   .|::....|.|..::.||||.|
  Fly     5 ACLFIVPIC--------------AAPTTQNVEADPNSRLMNNILSYVAEDSSACGTYFQYACGKY 55

  Fly    70 AT----------INAATSQKDTNIRQLMFANYLRRVRQVLNEPRISTDRPMEVRVKYFYESCLDT 124
            |.          |.....:.:.|:.|||...:.|......||..:      |.:|.:||.:|.:
  Fly    56 AVRHRDDPFTEIIQMLDHKVNGNLVQLMHELHQRSQSPGFNESSV------EAKVLHFYRTCRE- 113

  Fly   125 AALRTKQRSHLLSVL--------REFGGMPAVEGKSWDYVGFDAIEMMAQLLRRYG-KLTLLGVY 180
            |...|::..|.|.:.        .:|  ||  .|:.|....|..::.:..|. ||| ...|:.|.
  Fly   114 APPSTRKMEHYLRLAPPGQALTWPQF--MP--RGEPWPKAQFKWMKSLGHLY-RYGFTNVLVNVL 173

  Fly   181 VVPDHFNSQIKRLQLGQRLDLAESDEFASLWKKYALKMRLRNLLGLSEELARKTAEEIIELE--- 242
            |:....||  .|.:|...:...|.|              .::|.|....||   ..:||.:.
  Fly   174 VLRSSENS--NRFRLDISMPSLEGD--------------AQHLGGFLSTLA---TLQIIGVPTKS 219

  Fly   243 -LELSRSAFDHRMNRDPRLMRHLTMLSNMSDAYGPILNVTRFVT--SWLGSEYNLPVFESV---- 300
             |.|.|     ::.|....:|.||.:.:..::....|....:.|  :|.|...:: |..||
  Fly   220 ILPLVR-----KIRRLESAIRVLTEVDDDDESETWTLRQWEYKTGYAWQGFVESI-VGHSVSHHY 278

  Fly   301 ------PSYLFQVKKILLSTPNHVVANYMLSS----LLTDFEITANEEQQKVICHERITEL--FP 353
                  ..|...:|:::.||...|||||:::.    |:.|| |.:||.   :.|   :|::  ..
  Fly   279 VMQAQNAKYFTGLKRLMDSTDAEVVANYIMTRFVLYLIDDF-IDSNEH---IDC---VTDMRRNM 336

  Fly   354 DVVDHMVYH-------SLEQQNPYIANEMRSLWVELKSSFREMLSSPDIEWLEKQTREELLEKLN 411
            ::..:::|.       :|:|    ...|:..::.:|:..|...::         :.|..|..:.|
  Fly   337 NLASNLLYKERFLDPATLQQ----YTQEVTKVFEQLRRQFLLQIN---------ENRLGLTSEQN 388

  Fly   412 GMSFEIAGGQAVNF-------------EEQFGDLV--VSSADYYGNIQRLLEVKAR--ILRTDLL 459
            .|....|....:|.             ...:.|||  :...||......|||.:.|  :|:.:..
  Fly   389 SMVATKAQHVVLNIGNLPRGRDHRSFVSRHYEDLVFPLPDFDYAREHLNLLEFRTRKQVLQLNQS 453

  Fly   460 RESSSVYYY-----HGVTATPIYETETNLVVLPVSYMQHRYLWDDIYPAALKYGTLGFTMAHEMA 519
            ..:...::|     ..:::.|.|....|::|:|...:|..:...|.:. ..||..|||.:|||:.
  Fly   454 APTPDEFFYLSDPKTAMSSGPYYLMRLNIIVVPHGLLQEPFFAADSHD-IFKYSLLGFVLAHELM 517

  Fly   520 HGFDDLNRLYDSRGNLNDNWSTQTKVGFELVKNCLADQFSG---MLYGNLRLRRLKSQ--AESIA 579
            |..|.:...||..||:::                :..|.|.   .:.|...|.|..:|  .|.||
  Fly   518 HSVDTVGLYYDRYGNIHE----------------IGPQISSSPRFVAGLQCLNRNSTQYLDERIA 566

  Fly   580 DNVGIRIAQSAYWKWLDQVEMEETESLPHMTQSPEQLFFLSAAQFMCSDIYPERRANFVRNNFHP 644
            |..|:.:|.|.|::...|:.:.:..::|     |:|:|||:.|||.|.|..|   .|||.   |.
  Fly   567 DIAGLDLAYSTYFQNSSQMSLTDFTTIP-----PQQIFFLNLAQFFCGDGDP---INFVG---HD 620

  Fly   645 PYEARVFAMMINSPAFAEAFQCSNSSKMNPPNKCLMY 681
            ..|.|:..|:.....|.|||.|  .:|.|.|.||.::
  Fly   621 NDETRLQQMLNGFAPFHEAFGC--PAKSNQPEKCQLW 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	M13	55..678	CDD:341056	167/697 (24%)
Nepl6	NP_609023.3	M13	47..653	CDD:341056	166/692 (24%)