Protein Alignment Nepl17 and Nepl5

DIOPT Version :10

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Alignment Length: 768
• Identity: 182/768 - (23%)
• Similarity: 311/768 - (40%)
• Gaps: 171/768 - (22%)

  Fly     1 MERLPASACLIFVTLAVGSLAIQGGVFKELTTPL------GQQIMRIAKSAEMCSFMDTSVSPCD 59
            |.:|...|.|||      |||.:       |||.      ..|.::...:.::.|:|||...||:
  Fly     1 MLKLSLVAWLIF------SLAWR-------TTPTACRQTNAPQSVQEMLAEQLQSYMDTKARPCE 52

  Fly    60 DFYGYACGNYATINAATSQKDTNIR-------------QLMFANYL--------RRVRQVL---N 100
            :||.|||||:    ....|:..::|             |::..:.|        |::..:|   |
  Fly    53 NFYQYACGNW----QIQQQEQHSLRDRDWTRDRQRYQGQMLPTDTLGLIDHSVNRKLELLLRRRN 113

  Fly   101 EPRISTDRPMEVRVKYFYESCLDTAALRTKQRSHLLSVLREFGGMPAVEGKSWDYVG-------F 158
            |....:|..:..:::.:|.||........|:...||         |......|..||       |
  Fly   114 ESSFESDSSILEQMRLYYRSCKRLKPYNLKKYLQLL---------PPSNSTQWPSVGRGWRPERF 169

  Fly   159 DAIEMMAQLLRRYGKLTLLGVYVVPDHFNSQIKRLQLGQRLDLAESDEFASLWKKYALK------ 217
            |.|..:       |:|.|.|:       |..:.|.::..|.|  :|..::....|.:.:
  Fly   170 DWITTL-------GRLRLHGL-------NGVLLREEVLPRWD--DSRNYSIYVNKPSRQETQPMG 218

  Fly   218 ----MRLRNLLGLSEELARKTAEEIIELELELSRSAFDHRM-----NRDPRLMRHLTMLSNMSDA 273
                :.|...:|.::..|...|.::.:.|.:|      ||:     :..||.|: |..|    |:
  Fly   219 EGAMIELLLDIGQTKRTANALARQVDDFERKL------HRLQELEDDEGPREMQ-LGYL----DS 272

  Fly   274 YGPILNVTRFVTS-WLGSEYNLP---VFESVPSYLFQVKKILLSTPNHVVANYMLSSLLTDFEIT 334
            |.|.|....|:.. .:.||.:|.   :.|::| ||..:..::.|.....|.:|::...|...:..
  Fly   273 YLPQLRWLSFMRQVRIDSELDLRSTLIIENIP-YLRALSDLMESESPDTVCSYIMLKWLAFLKQQ 336

  Fly   335 ANEEQQKVICHERITELFPDVVDHMVYHSLEQQNPYIANEMRSLWVELKSSFREMLS------SP 393
            ...:..:..|...:....|.....:|  ..:..:|...:.:.||:..||..|.::|:      ||
  Fly   337 GPADISRGECVAALRRAMPLASSWLV--GQQFSDPESESYVSSLFQRLKVRFGQILAENRMRLSP 399

  Fly   394 DIEWLEKQTREELLEKLNGMSFEIAGGQAVNFE--EQFGDLV-VSSADYYGNIQRLLEVKARI-L 454
            .:..:       |.:||..:..::...|....|  ||:...: :|...:|||  :|:.::.|: .
  Fly   400 PLVHI-------LQQKLRAVRLQMGFFQTEEIEDVEQYHVRIDLSGHSFYGN--QLVLLRQRVEA 455

  Fly   455 RTDLL---------RESSSVYY----YHGVTATPIYETETNLVVLPVSYMQHRYLWDDIYPAALK 506
            ..|||         ...|::.|    :....::|:|....|||::|...:| ..:|.....|..:
  Fly   456 NHDLLYINVTNFANSTGSNLSYLSESWEASNSSPLYVRPRNLVLVPHGLLQ-LPIWHRNISALQQ 519

  Fly   507 YGTLGFTMAHEMAHGFDDLNRLYDSRGNL-----NDNWSTQTKVGFELVKNCLADQFSGMLYGNL 566
            :..:||.:|||:|||||.|...||:.||:     ....|.|.:.|.:    ||..|   |..|:
  Fly   520 HAVMGFVLAHELAHGFDMLGMDYDAMGNIMGPVEEIGASRQFRQGLQ----CLQQQ---MATGS- 576

  Fly   567 RLRRLKSQAESIADNVGIRIAQSAYWKWLDQVEMEETESLPHMTQSPEQLFFLSAAQFMCSD--- 628
                 |...|.:||.|.:|:|...::...|:.|..: ..||..:|  .||||::.|||.|..
  Fly   577 -----KWIDEKLADFVALRLAYETFFGVRDKREPRD-PLLPQFSQ--RQLFFITFAQFFCGRTPV 633

  Fly   629 IYPERRANFVRNNFHPPYEARVFAMMINSPAFAEAFQCSNSSKMNPPNKCLMY 681
            :.|  |:....:..|...|.||...:.|...|:..|.|...:||....:|.::
  Fly   634 LSP--RSQSEAHLKHAADELRVMQTLANFEEFSREFGCDKKAKMQASQRCRIW 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	M13	55..678	CDD:341056	164/703 (23%)
Nepl5	NP_609022.1	M13	48..682	CDD:341056	164/704 (23%)