Protein Alignment Nepl17 and Nepl4

DIOPT Version :9

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 716
• Identity: 163/716 - (22%)
• Similarity: 258/716 - (36%)
• Gaps: 200/716 - (27%)

  Fly    47 MCSFMDTSVSPCDDFYGYACG----NYATINAATSQKDTNIRQLMFANYLRRVRQVLNEPRI-ST 106
            :.|::|:..:||:|||.||||    .:.:...||...::.|.:    .|.....|:|..|.. ..
  Fly    50 LMSYVDSEKNPCEDFYAYACGKWRAKHGSHTTATMISESQINR----QYEDLFLQLLRNPSAPEY 110

  Fly   107 DRPMEVRVKYFYESC--------------LD---TAALRTKQRSHLLSVLREFGGMPAVEGKSWD 154
            ..||..:|...|:||              ||   .|:|.:....|||:.|..:|
  Fly   111 GYPMFAKVLAHYQSCIALEKPDLRRYIELLDRDLLASLNSTHWMHLLAALGRYG----------- 164

  Fly   155 YVG---------FDAIEMMAQLLRR------------YGKLTLLGVYVVPDH-FNSQIKRLQLGQ 197
            |.|         ::|...|..||..            |..|:..|....|.| ...|.:.|:  |
  Fly   165 YHGHYVQVEVRWYNATHHMIFLLPHNRHLNLSLTQDIYDALSQDGSSWPPLHQLQEQFRSLE--Q 227

  Fly   198 RL-DLAESDEFASLWKKYALKMRLRNLLGLSEELARKTAEEIIELELELSRSAFDHRMNRDPRLM 261
            .| .||:.......::.|:|......:.||..:.|.:|         :|.||...:
  Fly   228 NLVRLAKPHSADDTFRNYSLDQIRTEVPGLHWDEALRT---------QLGRSVPGN--------- 274

  Fly   262 RHLTMLSNMSDAYGPILNVTRFVTSWLGSEYNLPVFESVPSYLFQVKKILLSTPNHVVANYMLSS 326
             |:..:.:: ||...::.....|.:.|.:.|:|..|.|          .||..|::.:|.:
  Fly   275 -HVFQVDDL-DAIEGLVEYLNTVDTLLLNRYSLARFLS----------HLLELPHNPLATW---- 323

  Fly   327 LLTDFEITANEEQQKVICHERITELFP-----------------DVVDHMVYHSLEQQNPYIANE 374
                 |.......:..|.|.|.:...|                 ::|.|.|:..|:.|
  Fly   324 -----ESGQRSRGRNCIRHMRRSVYLPMNYVYERSFYSRRRHADELVIHSVFQQLQSQ------- 376

  Fly   375 MRSLWVELKSSFREMLSSPDIEWLEKQTREELLEKLNGMSFEIAGGQAVNFEEQF---GDLVVS- 435
                 :||:........|.|:.       :.|..|::.|...: |....|..|||   .|...|
  Fly   377 -----LELRVQHNAFNLSQDLV-------KSLQAKVHQMRINV-GNLPPNVTEQFYWDSDRRWSV 428

  Fly   436 SADYYGN-IQRLLEVKARI--LRTDLLRESSSVYY---YH------GVTATPIYETETNLVVLPV 488
            ..|:|.| :..||.....:  |.:...:|...::|   .|      .:.|||.:....|::.:|.
  Fly   429 GRDFYENHLNSLLYYYTLVADLESSSDQEERDIWYSFNMHTPEFPDNIDATPYFYCLGNIIFVPY 493

  Fly   489 SYMQHRYLWDDIYPAALKYGTLGFTMAHEMAHGFDDLNRLYDSRGNLNDNWSTQTKVGFELVKNC 553
            ||::..:...:.:||.| ||.|..|:.||:.|.||.....||::|||.:
  Fly   494 SYVKRPFFDANFWPALL-YGDLANTLGHEIMHAFDTDLVDYDAQGNLRN---------------- 541

  Fly   554 LADQFSGMLYGNLRLRRLKSQA----ESIADNVGIRIAQSAY-WKWLDQVEMEETESLPHMTQSP 613
            .:||...:...|..:..|.|.|    |..:|..|.|:|...| ..||              |:|.
  Fly   542 FSDQLGEVELYNGAVGCLNSSAVMLNERTSDVSGSRLAMQTYGGDWL--------------TRSG 592

  Fly   614 E-QLFFLSAAQFMCSDIYPERRANFVRNNFHPPYEARVFAMMINSPAFAEAFQCSNSSKMNPPNK 677
            . :|:||..|.|.|.|         ..:.:|.....|:...:...|.|||.|:|...|.|...::
  Fly   593 NGRLYFLQFAHFFCGD---------EGDQYHDSGSQRLNYALGQVPQFAEVFRCHVGSGMTSADQ 648

  Fly   678 C 678
            |
  Fly   649 C 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	PepO	49..672	CDD:226118	161/706 (23%)
		M13	55..678	CDD:189000	160/706 (23%)
Nepl4	NP_609019.1	PepO	51..643	CDD:226118	161/707 (23%)
		GluZincin	59..649	CDD:301352	160/705 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920