Protein Alignment Nepl17 and goe

DIOPT Version :10

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_573160.1
• Gene: goe / 32660
• FlyBaseID: FBgn0027528
• Length: 879
• Species: Drosophila melanogaster
• Alignment Length: 822
• Identity: 162/822 - (19%)
• Similarity: 287/822 - (34%)
• Gaps: 237/822 - (28%)

  Fly     6 ASACLIFVTLAVGSLAIQGGVFKELTTPLGQQIMRIAKSAEMCSFMDTSVSPCDDFYGYACGNYA 70
            |..|.:.:.:.:..||....|...|..||......:..|.::..:.:||.|||.:.|.:||||:|
  Fly   134 ACLCALLLLIIILLLAFWPEVPFYLRAPLCLDKECVESSRQLLLWANTSKSPCHETYEWACGNFA 198

  Fly    71 TINAATSQKDTNIRQLMFANY----LRRVR---------QVLNE--------PRISTDRPMEVRV 114
            :               .:||:    ::|..         |.|||        |. |.:..:|..|
  Fly   199 S---------------DYANHEYFVIKRGEWNYETYNEYQELNELNRFIAMLPN-SQEGSVESTV 247

  Fly   115 KYFYESCLDTAALRTKQRSHLLSVLREFGGMPAVEG----------KSWDYVGFDAIEMMAQLLR 169
            ...|.||.:|..|...|...||.     ..:.||.|          :||:|.     .::..|..
  Fly   248 SSLYRSCRETDVLDKSQSDLLLK-----RAINAVYGWQAFRDSNRLQSWEYK-----RVLVVLQA 302

  Fly   170 RYGKLTLLGV-----------YVV---------PDHF---NSQIKRLQLGQRLDLAESDEFASLW 211
            ::|......|           ||:         ||.:   |...:.:..|.:|          |.
  Fly   303 KHGIFPYYRVTVENGFSNPHDYVITLDEGELGLPDKYFYGNDADEEVVRGYKL----------LL 357

  Fly   212 KKYALKMRLRNLLGLSEELARKTAEEIIELELELSRSAFDHRMNRDPRLMRHLTMLSNMSDAYGP 276
            :.:|:.|      |:....|...|::|...|               .|::.|:.  ...:||..|
  Fly   358 RDFAINM------GIVSREADLFADDIFHYE---------------RRIVNHIE--DAKADANRP 399

  Fly   277 ILNVTRFVTSWLGSEYNLPVFESVPSYLFQVK------------------KILLSTP------NH 317
            |..:.|.....:.:. :||:.||:.:...:.|                  .:||||.      |.
  Fly   400 INKLMRLADLKIKAP-SLPILESLQAIFPKTKITEDTEVLVRDPEVMHALSVLLSTSDKKPINNF 463

  Fly   318 VV---ANYMLSSLLTDFEITAN-----------EEQQKVICHERITELFPDVVDHMVYHSLEQQ- 367
            :|   |..||..|..::...|.           ...:.:||.:.:.:..|..||.:......||
  Fly   464 IVWSLARKMLPHLSKEYRTLAETFDHALYGRTASYPRWLICSKVVRDWLPFAVDALQQQPPRQQF 528

  Fly   368 ----------NPYIANE--MRSLWVELKSSFREMLSSPDIEWLEKQTREELLEKLNGMSFEIAGG 420
                      |....||  ::.::..|::..::.|.  ..:|||...|:.:.:|||.|..:.  |
  Fly   529 ETMTSKSRGLNKTQGNEELLKLMFFSLRNQLKDSLE--QAKWLEPAARQFIQKKLNEMRLQF--G 589

  Fly   421 -------QAVNFEEQFGDLVVSSADYYGNIQ-----RLLEVKARILRTDLLRESSSVYYYHGVTA 473
                   |.....:.:.:|::::..:..:::     |..:::.::....:|....|..|......
  Fly   590 IPDEVLQQPTYLAQYYNELILNNVFFVEHLEWIWTFRRSQMEKKLGPLAILDVIVSEMYTRDNPQ 654

  Fly   474 TPIYETETNLVVLPVSYMQHRYLWDDIYPAALKYGTLGFTMAHEMAHGFDDLNRLYDSRGNLNDN 538
            ...|..:.|::::....:...| :|..||.|:.:..:          |.|.|..|.|:.......
  Fly   655 AIAYSNKLNMLLVSKVLISSNY-YDYRYPVAVNFARI----------GTDILEALIDNFSTFLLQ 708

  Fly   539 WSTQ-TKVGFELVK--------NCLA------------DQFSGMLYG-NLRLRRLKSQAESIADN 581
            ::|| |.:.....:        ||||            :..|..|.. ::.|...::.|.::::.
  Fly   709 FNTQSTDISDAAPEIRYAQPDVNCLAAGQPPRLVHELNELSSNALKSFHVTLSAARTAARALSNF 773

  Fly   582 VGIRIAQSA-YWKWLDQVEMEETESLPHMTQSP-------EQLFFLSAAQFMCSDIYPERRANFV 638
            |....|.|| ....:||....|...|....:.|       .:||.||..|..||....::  ::.
  Fly   774 VNAIDAGSAIQGSGIDQANTYEALGLTRRLRIPGLRSFNENELFTLSYMQQHCSTTIADK--DYA 836

  Fly   639 RNN------------FHPPYEARVFAMMINSPAFAEAFQCSN 668
            |..            |:..::...|.....:.|.||| .|||
  Fly   837 RIKPLVESQLAESYLFNATWQHIQFLPRSTNCAAAEA-TCSN 877

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	M13	55..678	CDD:341056	151/773 (20%)
goe	NP_573160.1	GluZincin	184..>692	CDD:472708	109/582 (19%)