Protein Alignment Nepl17 and Nepl3

DIOPT Version :10

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 723
• Identity: 153/723 - (21%)
• Similarity: 253/723 - (34%)
• Gaps: 229/723 - (31%)

  Fly    37 QIMRIAKSAEMCSFMDTSVSPCDDFYGYACGNYATINAATSQKDTNIRQLMFANYLRRVRQVLN- 100
            :||:     .|...||..|.||.:||.            :|||  |::...||....:.:.:.:
  Fly    29 EIMK-----RMLDDMDEKVEPCHNFYN------------SSQK--NLKWHAFATVSDQFQLLFDG 74

  Fly   101 -EPRISTDRPMEVRVKYFYESCLDTAALRTKQRSHLLSVLREFGGMPAVEGKSWDYV-------- 156
             |..:......|.:::..|:.|      .|.:|.   |:||.|..:...|..:|.::
  Fly    75 IENEVFEKHSFEEKLQRLYKIC------STMERP---SLLRYFELVKPGEDLNWPFLTPRGGKWP 130

  Fly   157 --GFDAIEMMAQLLRRYGKLTLLGVYVVPDHFNSQIKRLQLGQRLDLAESDEFASLWKKYALKMR 219
              .|..:|.:|: |||||             ||..:..:.:.|..:...........|||....|
  Fly   131 KEKFQWMEALAR-LRRYG-------------FNDIMFGMSIRQDPNSDSGQPIVVFEKKYDSLFR 181

  Fly   220 ----LRNLLGLSEELARKTA--EEIIELELELSRSAFDHRMNRDPRLMRHLTMLSNMSDAYGPIL 278
                |:| :||..:||::.|  :..|: |:..|...|:| ..||...::.:::  ...:.||  :
  Fly   182 FIESLQN-IGLPPKLAKEIAPLDNAIQ-EMYKSDMKFEH-YARDAAPVKRISL--GQLEIYG--V 239

  Fly   279 NVTRFVTSWLGSEYNLPVFESVPS--YLFQVKKILLSTPNHVVANYM------------------ 323
            ::|:::....|..::......|.:  ||..::.::.:.|:.|||||:
  Fly   240 SLTKYLEIVFGRPFSPDFVVHVENLYYLRGLQNLMTAVPSQVVANYLTARFSFYIMFTFMKHGDS 304

  Fly   324 -LSSLLTDFEITANEEQQKVICHERITELFPDVVDHMVYHSLEQQNPYIANEMR-SLWVELKSSF 386
             ::::....|..:|     ::..|||       :......|.:.|...|.:.:| .|.:.|:
  Fly   305 CVTTMRQSMEFASN-----LLFEERI-------LGRKKLRSYQNQAGKIFDAIRQQLNIRLE--- 354

  Fly   387 REMLSSP--DIEWLEKQTREELLEKLNGMSFEIAGGQAVNFEEQFGDLVVSSADYYGNIQ----- 444
            |.:|..|  :|..|:|        ||||:|..|..........:|      ...||..::
  Fly   355 RNVLKLPPAEISLLQK--------KLNGLSLSIGNLPGKAGHRRF------VTRYYKELEFADDE 405

  Fly   445 -------RLLE--VKARILRTDLLRESSSVYYYHGVTATPI--------YETETNLVVLPVSYMQ 492
                   ::||  .:|.:...|........|..|   :.||        ||...|.:     |:.
  Fly   406 ELATAHLKVLEHRTRAELSLLDQPNFKDRRYMLH---SYPISNFFFETAYEENGNTI-----YVA 462

  Fly   493 HRYLWD--------DIYPAALKYGTLGFTMAHEMAHGFDDLN---------RLYDSRGNLNDNWS 540
            :.:|.|        ||:    |...||.....||...||..|         :|:|      ||
  Fly   463 YDFLADASFDPDSHDIF----KVTPLGIRFGLEMLKSFDLFNCKHHKVNMLQLFD------DN-- 515

  Fly   541 TQTKVGFELVKNCLADQFSGMLYGNLRLRRLKSQAESIADNVGIRIAQSAYWKWLDQVEMEETES 605
            ..|..|.|.|.....|             .|.||.:...  |.:.:...||:....:....:
  Fly   516 QITTAGDECVSAWTQD-------------NLLSQRDQYL--VVLHLVHEAYFAEGSKFSQRQ--- 562

  Fly   606 LPHM-TQSPEQLFFLSAAQ-------FMCSDIYPERRANFVRNNFHPPYEARVFAMMINS----P 658
             |:. |.|..:|||....|       :..||        ||..           ...|||    |
  Fly   563 -PNFTTMSLRELFFFRFGQSSFGQTLYFGSD--------FVEG-----------GSPINSLTRLP 607

  Fly   659 AFAEAFQC 666
            .|...|.|
  Fly   608 VFVRTFNC 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	M13	55..678	CDD:341056	148/705 (21%)
Nepl3	NP_608904.1	GluZincin	42..>434	CDD:472708	95/464 (20%)