Protein Alignment Nepl17 and Nep1

DIOPT Version :9

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001284925.1
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Alignment Length: 721
• Identity: 187/721 - (25%)
• Similarity: 314/721 - (43%)
• Gaps: 122/721 - (16%)

  Fly    36 QQIMRIAKSAEMCSFMDTSVSPCDDFYGYACGNYATI--------NAATSQKDTNIRQLMFANYL 92
            |:.:|.|  |.:.|.||.:..||:||:.||||.:..:        :.:|.:..::.:|::
  Fly   176 QECVRTA--ASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLSDQQQVI----- 233

  Fly    93 RRVRQVLNEPRISTDRPMEVRVKYFYESCLDTAALRTKQRSHLLSVLREFGGMPAVEGKSWDYVG 157
              :|.||.||....|....::.|.|::||:|...:|......|..||:..||.|.:| ::|....
  Fly   234 --LRAVLEEPIDERDNKATIKAKTFFKSCMDIPQIRKIGTGRLKQVLQSLGGWPVIE-RNWSPPA 295

  Fly   158 FDAIE-MMAQLLRRYGKLTLLGVYVVPDHFNSQIKRLQLGQRLDLAESDEFASLWKKYALKMRLR 221
            ..::| :|.||...|.:..::.:||..|..||.:..||:.|.       ::|...:.|.||....
  Fly   296 DLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQL-------QYALPSRDYYLKESSA 353

  Fly   222 N--------------LLGLSEELARKTAEEIIELELELSRSAFDHRMNRDPRLMRHLTMLSNMSD 272
            |              |||.....|....|:::..|.:|...:.......|..|:....:|..:.:
  Fly   354 NDRRAYHRYMTQVALLLGADPATAAAELEKVVLFETQLVNVSLPEADRHDTSLVYRKMLLPELQE 418

  Fly   273 AYGPILNVTRFVTSWLGSEYNLPVFESVP------SYLFQVKKILLSTPNHVVANYML------- 324
            .. |.:....::.:.||.  .:|:.|..|      .||.::.|||..|...||.||||
  Fly   419 LV-PEVQWQEYLQAALGP--GIPLQEDEPLVTYGLHYLTEMGKILAHTDRRVVHNYMLWRLVMSL 480

  Fly   325 -SSLLTDFEITANEEQQKVI------------CHERITELFPDVVDHM-VYHSLEQQNPYIANEM 375
             |.::.::: ....|.:|::            |.|...:.....|..: :..:..|::..:|.||
  Fly   481 MSHMIDEYQ-RERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQESKEVALEM 544

  Fly   376 RSLWVELKSSFREMLSSPDIEWLEKQTREELLEKLNGMSFEIAGGQ----AVNFEEQFGDLVVSS 436
            ..   .::::|.|:|:..|  |::.:||....||.:.|:..|...:    |...|:::.:|.:..
  Fly   545 IH---TIRAAFNELLAEND--WMDDETRAVAKEKADSMNERIGYPELLTNATELEQEYVNLTIVP 604

  Fly   437 ADYYGNIQRLL----EVKARILRTDLLRESSSVYYYHGVTATPIYETETNLVVLPVSYMQHRYLW 497
            .::..|:..:|    |...|:||..:.:|.   :..........|....|.:|.|...:|..: :
  Fly   605 DNFINNVLSILQWESEKMLRLLRQPVDKEK---WTTEPAVVNAFYNPNKNDIVFPAGILQPLF-Y 665

  Fly   498 DDIYPAALKYGTLGFTMAHEMAHGFDDLNRLYDSRGNLNDNWSTQTKVGFELVKNCLADQFSGML 562
            ...:|.:|.||.:|..:.||:.|||||..|.:|..||:...|:..|...|.....|:.||:|
  Fly   666 SQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYS--- 727

  Fly   563 YGNLRLRRLK------------SQAESIADNVGIRIAQSAYWKWLDQVEMEET-----ESLPHMT 610
                   |.|            :|.|:||||.|::.|..||.||       ||     :.||.:.
  Fly   728 -------RYKINEVDMFMDGRMTQGENIADNGGLKQAFRAYKKW-------ETLHGREQQLPGLN 778

  Fly   611 QSPEQLFFLSAAQFMCSDIYPERRANFVRNNFHPPYEARVFAMMINSPAFAEAFQCSNSSKMNPP 675
            .:.:|||||:.||..|..:.||.....:|:..|.|...||...:.||..||.|::|...|.|||.
  Fly   779 MTHDQLFFLNYAQIWCGSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPA 843

  Fly   676 NKCLMY 681
            .||.::
  Fly   844 EKCSVW 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	PepO	49..672	CDD:226118	178/697 (26%)
		M13	55..678	CDD:189000	178/697 (26%)
Nep1	NP_001284925.1	M13	194..847	CDD:189000	179/697 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469688
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850