Protein Alignment Nepl17 and Mme

DIOPT Version :10

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_036740.1
• Gene: Mme / 24590
• RGDID: 3098
• Length: 750
• Species: Rattus norvegicus
• Alignment Length: 762
• Identity: 186/762 - (24%)
• Similarity: 321/762 - (42%)
• Gaps: 137/762 - (17%)

  Fly    10 LIFVTLAVGSLAI----QGGVFKELTTPLGQQIMRIAKSAEMCSFMDTSVSPCDDFYGYACGNYA 70
            |:...:||..:|:    ..|:.|....        |..:|.:...||.|..||.||:.||||.:.
  Rat    36 LLLTIIAVTMIALYATYDDGICKSSDC--------IKSAARLIQNMDASAEPCTDFFKYACGGWL 92

  Fly    71 TINA--ATSQKDTNIRQLMFANYLRR-----VRQVLNEPRISTDRPMEVRVKYFYESCLDTAALR 128
            ..|.  .||.:.:|.      :.||.     ::.||.||: :.|.....:.|..|.||::.:|:.
  Rat    93 KRNVIPETSSRYSNF------DILRDELEVILKDVLQEPK-TEDIVAVQKAKTLYRSCINESAID 150

  Fly   129 TKQRSHLLSVLREFGGMPAVEGKSWDY---VGFDAIEMMAQLLRRYGKLTLLGVYVVPDHFNSQI 190
            ::....||::|.:..|.| |..::|:.   ..:.|.:.:|||..:|||..|:..:|..|..||..
  Rat   151 SRGGQPLLTLLPDIYGWP-VASQNWEQTYGTSWTAEKSIAQLNSKYGKKVLINFFVGTDDKNSTQ 214

  Fly   191 KRLQLGQ-RLDLAESD--EFASLWKK-----------YALKMRLRNLLGLSEELARKTAEEIIEL 241
            ..:...| ||.|...|  |...::|:           .|..:|....|.:.|........:::||
  Rat   215 HIIHFDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEQRLPIDENQLSLEMNKVMEL 279

  Fly   242 ELELSRSAFDHRMNRDPRLMRHLTMLSNMSDAYGPILNVTRFVTSWLGSEYNLPVFESV------ 300
            |.|::.:........||.|:.:...|:.:.:.:...:|...|  ||  |.:...:..:|
  Rat   280 EKEIANATTKPEDRNDPMLLYNKMTLAKLQNNFSLEINGKPF--SW--SNFTNEIMSTVNINIQN 340

  Fly   301 --------PSYLFQVKKILLSTPNHVVANYM--------LSSLLTDFEITANEEQQKVI------ 343
                    |.||.::|.||.......:.|.|        :|||..:::.:.|..::.:.
  Rat   341 EEEVVVYAPEYLTKLKPILTKYSPRDLQNLMSWRFIMDLVSSLSRNYKESRNAFRKALYGTTSET 405

  Fly   344 -----CHERITELFPDVVDHMVYHSLEQQNPYIANEMRSLWVELKSSFREML--SSPDIEWLEKQ 401
                 |...:.....:.|..:...:.      .|.|.:.:..:|.:..||:.  :..|:.|::.:
  Rat   406 ATWRRCANYVNGNMENAVGRLYVEAA------FAGESKHVVEDLIAQIREVFIQTLDDLTWMDAE 464

  Fly   402 TREELLEKLNGMSFEIAGGQAVNFEEQFG--DLVVSS---------------ADYYGN-IQRLLE 448
            |:::..||            |:..:|:.|  |.::|:               .:|:.| ||.|..
  Rat   465 TKKKAEEK------------ALAIKERIGYPDDIISNENKLNNEYLELNYKEEEYFENIIQNLKF 517

  Fly   449 VKARILRTDLLRE--SSSVYYYHGVTATPIYETETNLVVLPVSYMQHRYLWDDIYPA----ALKY 507
            .:::.|:.  |||  ....:..........|.:..|.:|.|...:|..:     :.|    :|.|
  Rat   518 SQSKQLKK--LREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPF-----FSARQSNSLNY 575

  Fly   508 GTLGFTMAHEMAHGFDDLNRLYDSRGNLNDNWSTQTKVGFELVKNCLADQFSGM---LYGNLRLR 569
            |.:|..:.||:.|||||..|.::..|:|.|.|:.|:...|:....|:..|:...   |.|...|.
  Rat   576 GGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSANNFKDQSQCMVYQYGNFTWDLAGGQHLN 640

  Fly   570 RLKSQAESIADNVGIRIAQSAYWKWLDQVEMEETESLPHMTQSPEQLFFLSAAQFMCSDIYPERR 634
            .:.:..|:||||.||..|..||..::.  :..|.:.||.:..:.:|||||:.||..|....||..
  Rat   641 GINTLGENIADNGGIGQAYRAYQNYVK--KNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYA 703

  Fly   635 ANFVRNNFHPPYEARVFAMMINSPAFAEAFQCSNSSKMNPPNKCLMY 681
            .|.::.:.|.|...|:...:.||..||:||.|..:|.|||..||.::
  Rat   704 VNSIKTDVHSPGNFRIIGTLQNSAEFADAFHCRKNSYMNPERKCRVW 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	M13	55..678	CDD:341056	173/708 (24%)
Mme	NP_036740.1	Stop-transfer sequence. /evidence=ECO:0000255	16..23
		M13	79..748	CDD:341056	174/707 (25%)