Protein Alignment Nepl17 and nep-25

DIOPT Version :9

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_495164.2
• Gene: nep-25 / 191543
• WormBaseID: WBGene00022874
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 720
• Identity: 127/720 - (17%)
• Similarity: 222/720 - (30%)
• Gaps: 267/720 - (37%)

  Fly     4 LPASACLIFVTLAVGSLAIQGGVFKELTTPLGQQIMRIAKSAEMCSFMDTSVSPCDDFYGYACGN 68
            ||.....:|:.......::...:.:|          .|.|.|      |.||.||.|||.:.|
 Worm     5 LPFFIFSVFILFCTSKASLPKNIIQE----------HIKKHA------DFSVDPCVDFYAHVC-- 51

  Fly    69 YATINAATSQKDTNIRQLMFANYLRRVRQVLNEPRISTDRPMEVRVKYFYESCLDTAALRTKQRS 133
                                                    |.:|. :||.|.
 Worm    52 ----------------------------------------PWKVE-RYFMED------------- 62

  Fly   134 HLLSVLREFGGMPAVEGKSWDYVGFDAIEMMAQLLRRYGKLTLLGVYVVPDHFNSQIKRLQLGQR 198
              ||.|:                    ..|:|:..:::.|.         |.|..:
 Worm    63 --LSKLK--------------------AGMVAKYRKKHPKF---------DKFKGE--------- 87

  Fly   199 LDLAESDEFASLWKKYALKMRLRNLLGLSEELARKTAEEIIELELELSR--------SAFDHRMN 255
                  |.||                 ::|.|.:...|: ::.|.:.|:        ||.|:|
 Worm    88 ------DAFA-----------------IAEALKQLNIEQ-LKSECKPSKPRLSSFFISAQDNR-- 126

  Fly   256 RDPRLMRHLTMLSNMSDAYGPILNVTRFVTSWLGSEYNLPVFESVPSYLFQV---------KKIL 311
                      .:.|:.:...|            |.| |.|..|.....:.:|         :.:|
 Worm   127 ----------TIENVDEVLFP------------GFE-NYPCEEKAAIIIKEVGEIEDYTTTRSVL 168

  Fly   312 LSTPNHVVANYMLSSLLTDFEITANEEQQKVICHERITELFPDVVDHMV--------YHSLEQQN 368
            :|..|    .::.|.|:...::.|          .::...|..|:...:        |.::||..
 Worm   169 VSAVN----GFITSKLVEKLDVKA----------RKLFNKFKSVISKEIIKTPWAKNYKAIEQYV 219

  Fly   369 PYIANEMRSLWVELKSSFREMLSSPDIEWLEKQTREELLEKLNGMSFEIAGGQAVNFEEQFGDLV 433
            ..::|.....:.:::.:.::.:.      |.:.|.::..:||:           |.|.:...:||
 Worm   220 EALSNITFRTFADVRITVKKSME------LYESTEKDCRKKLD-----------VAFSQPTAELV 267

  Fly   434 VSSADYYGNIQRLLEVKARILRTDLLRESSSVYYYHGVTATPIYETETNLVVLPVSYMQHRYLWD 498
            ..........:.|.|....|...|.......|:.........:|.....|::|...|      :.
 Worm   268 CKGVATRKAEELLDEPIEDIFPQDQAGILKDVWQMFNSFDNSVYIGNEFLLLLNTDY------FS 326

  Fly   499 DIYPAALKYGTLGFTMAHEMAHG--FDD------LNRLYDSRGNLNDNWSTQTKVGFELVKNCLA 555
            |:      ||::||:|.||:.|.  |||      |::|:....:...:.:.:|...|..|
 Worm   327 DL------YGSIGFSMIHEIMHTLVFDDNDLDKPLSKLWTKNADCVKDQALKTCETFPTV----- 380

  Fly   556 DQFSGMLYGNLRLRRLKSQA-------ESIADNVGIRIAQSAYWKWLDQVEMEETESLPHMTQSP 613
                      ..:..:|...       |..||....|||    |:..:.....:|....:.....
 Worm   381 ----------TEMHNMKPACNTTVTFEEDAADLAAYRIA----WRIYENSYARKTVVPNYEALDK 431

  Fly   614 EQLFFLSAAQFMCSDIYPERRANFVRNNFHPPYEARVFAMMINSPAFAEAFQCSNSSKM--NPPN 676
            :||||..||.|.|:.....|..  .:|..|.....||.::|.....|::||:|..:.||  |...
 Worm   432 KQLFFYGAAVFFCNQDGMSRVP--FQNLAHSNNYQRVNSLMSQMKQFSDAFKCKPTDKMITNRAK 494

  Fly   677 KCLMY 681
            .|.:|
 Worm   495 HCELY 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	PepO	49..672	CDD:226118	115/662 (17%)
		M13	55..678	CDD:189000	116/664 (17%)
nep-25	NP_495164.2	Peptidase_M13	308..496	CDD:279739	51/220 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910