Protein Alignment Nepl17 and nep-24

DIOPT Version :10

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_503005.3
• Gene: nep-24 / 190993
• WormBaseID: WBGene00013786
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 614
• Identity: 127/614 - (20%)
• Similarity: 248/614 - (40%)
• Gaps: 126/614 - (20%)

  Fly     2 ERLPASACLIFVT----LAVGSLAIQGGVFKELTTPLGQQIMR----IAKSAEMCSFMDTSVSPC 58
            |:||....|:.:|    ||:|:           |||..:.:..    |..:..:.::.|.||.||
 Worm     8 EKLPGFMLLLLLTCTAPLAIGA-----------TTPATRNVCNTPACITLAHMLHNYHDPSVDPC 61

  Fly    59 DDFYGYACG---NYATINAATSQKDTNIRQLMFANYLRRVRQVLNEPRISTDRPMEVRVKYFYES 120
            |:|:.:|||   .:.|.:..| :|...|..:| ..:|::     ||...|..   |..::..|::
 Worm    62 DNFHQFACGREHEHETEDIYT-KKTKTINNIM-KRFLKK-----NETSRSKS---ENAMRTLYKA 116

  Fly   121 C----LDTAALRTKQRSHLLSVLREFGGMPAVEGKSWDYVGFDAIEMMAQLLRRYGKLTLLGVYV 181
            |    .::.|.|.|....:...::..|..|.|:.| ||...||..:.:..|: |.|:.. .|::.
 Worm   117 CKTLEKNSTASRNKALQDIFQDIQSIGAWPVVDDK-WDESKFDLNDFLVNLV-RLGRKN-FGLFQ 178

  Fly   182 VPDHFNSQIKRLQLG------QRLDLAESDEFASLWKKYALKMRLRNLLGLSEELARKTAEEIIE 240
            :..:.|  ::...:|      ..:||.::  .:.:.|..:::...:.||   ::||     |.:.
 Worm   179 MARYVN--VRNFAIGPEAAWRHNVDLGKT--ISEILKANSVQTNNKKLL---DDLA-----EYVN 231

  Fly   241 LELELSRSAFDHRMNRDPRLMRHLTMLSNMSDAYGPILNVTRFVTSWLGSEYNLPVFESVPSYLF 305
            ||..||:    |:.|    .::...:.|..||....: |.:|.|...:..: ...:|..|...::
 Worm   232 LEKALSQ----HKFN----TVQPGYIFSERSDFVSSV-NFSRLVLEMMSPD-KRTLFPEVYQIMY 286

  Fly   306 ------------QVKKILLSTPNHVVANYMLSSLLTDFEITANEEQQKVICHERITELFPDVVDH 358
                        .::.|:.:|....:|||::...:...............|.:::....|.....
 Worm   287 LTNTSLFFGKNNNLETIIRNTSKRALANYLIFKFIDTSIADLTYGSPSAFCEQKVINFLPRAALR 351

  Fly   359 MVYHSLEQQNPYIANEMRSLWVELKSSFR----EMLSSPDIEWLEKQTREELLEKLNGMSFEIAG 419
            ..|.:      :|:.|.|....:|..:.:    :::.:.|  |:..::::..:::::.|:..|
 Worm   352 AFYRN------FISKENRKKITKLTEATQVQLLKIIGATD--WMSIKSKKIAMDRVSSMNMVI-- 406

  Fly   420 GQAVNFEEQ------FGDLVVSSADYYGNIQRLLEVKARILRTDLLRESSSVYY---------YH 469
            |....|:..      |..|.:||:|.|..:.|      :|.|  .:||....||         :.
 Worm   407 GYPDYFDPPGKLDGLFEHLNLSSSDTYYTVVR------KINR--FMREQEMDYYTGEVPYYPLFP 463

  Fly   470 GVTATPIYETETNLVVLPVSYMQHRYLWDDIYPAALKYGTLGF---TMAHEMAHGFDDLNRLYDS 531
            |:....:|....|.:::...:....: :|..:|   .|..:.|   |:||||.|.|..  .|.|.
 Worm   464 GLMTNAMYNANDNNLMIFAPFFDDPF-FDSSFP---DYANIAFTSNTLAHEMGHTFSP--HLMDI 522

  Fly   532 RGNLNDNWSTQTKV-GFELVKNCLADQFS 559
            .....:.|.|..:. .:|....||.||::
 Worm   523 MTGTTEVWLTPKETEEYEKRVKCLEDQYT 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	M13	55..678	CDD:341056	113/553 (20%)
nep-24	NP_503005.3	GluZincin	58..561	CDD:472708	113/553 (20%)