Protein Alignment Nepl17 and nep-22

DIOPT Version :9

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_509528.1
• Gene: nep-22 / 181144
• WormBaseID: WBGene00020788
• Length: 798
• Species: Caenorhabditis elegans
• Alignment Length: 847
• Identity: 171/847 - (20%)
• Similarity: 311/847 - (36%)
• Gaps: 234/847 - (27%)

  Fly     7 SACLIFVTLAVGSLA----IQGGVFKELTTPLGQQIMRIAKSAEMCSF----------------- 50
            :|.:|.|.:|:|||.    |.|.|....||.....:.....:.::.|.
 Worm    11 AAVVIAVGIAIGSLVLNIIILGNVNTLTTTVNNNPVYHYTPAPQVNSTPGTVNTSPSYTQAANYL 75

  Fly    51 ---MDTSVSPCDDFYGYACGNYATINAATSQKDTNIRQL--------------MFANYLRRVRQV 98
               :|.:|.||.|||.:.|..:.        ::|::::|              :::..:..:.::
 Worm    76 LNGLDDTVDPCQDFYAFTCNKFL--------QNTDLQKLGRSRLGTYDQAQVDVYSEIVAALSKI 132

  Fly    99 LNEPRISTDRPMEVRVKYFYESCLDTAALRTKQRSHLLSVLRE-FGGMPAVEGKSWDYVG----- 157
              :...:|....|...|..:|:|.:..|....:.:.:.:.:.. |||:|        :.|
 Worm   133 --DVTSTTTSKTERITKAAFETCKNNLASPADKTAVVYAEITSLFGGVP--------FFGEPLKT 187

  Fly   158 -FDAIEMMAQLLRRYGKLTLLGVYVVPDHFNSQIKRLQLG-QRLDLAESDEFASLWKKYALKMRL 220
             .|...:..|:.:::...||.......|:.:.....|..| ..|.||. |.:..  .:|..::..
 Worm   188 NVDYWMVAGQIEQKHAVGTLTYTIASSDYKDHTKNALYTGPPGLSLAR-DFYVK--PQYIAEVNQ 249

  Fly   221 R-----NLLGLSEELARK---------TAEEIIELELELSRSAFDHRMNRDPRLMRHLTMLSNMS 271
            |     :||......|:|         .|:|::..|::::.:::..            .:|.|..
 Worm   250 RVSDVNDLLTAFANAAKKNVGADALLAAAQEVVNFEVQIAMASWPD------------DLLRNYQ 302

  Fly   272 DAYGPILNVTRFVT--------SWLG------------SEYNLPVFESVPSYLFQVKKIL--LST 314
            ..|.| .|:....|        |:||            :.||:.|.|  |||...:..:.  .::
 Worm   303 QQYNP-YNIASATTAYRAINWKSYLGQLFHGVASDADQANYNIVVTE--PSYFAWLNSVFDGKTS 364

  Fly   315 PNHVVANYMLSSLLTDFEITANEEQQKVI-----------------------------------C 344
            .:.||||||::.||.|.....|....||.                                   |
 Worm   365 NSTVVANYMIAQLLADESDFINPATAKVSSDTNYIHYALRNGRGIKKIGKREYRMADLDGISEGC 429

  Fly   345 HERITELFPDVVDHMVYHSLEQQNPYIANEMRSLWVELKSSFREMLSSPDIEWLEKQTREELLEK 409
            .:.:|...|....::...|..::|. :..:::.....:.::|:.|:.|  :.|::..::.....|
 Worm   430 MDLLTAYMPYGTGYVYVKSKSERNK-VQADVKDQTTLIINNFQGMIDS--LNWMDTFSKNRAHNK 491

  Fly   410 LNGMSFEIAGGQAVNF---EEQFGDL--------------------VVSSADYYG---NIQRLLE 448
            .:.:        ..||   |..|||.                    .....|.||   .:::.:|
 Worm   492 SDSL--------VKNFGWPEAMFGDFNDFTTVDAYNQDYASIIDLYTKDKNDIYGIFAVLKKGME 548

  Fly   449 VKA--RIL-----RTDLLRESSSVYYYHGVTATPIYETETNLVVLPVSYMQHRYLWDDIYPAALK 506
            |:.  ||:     ||:.|:..:.|..:        |:.|.|.:..|.:.....| ::..||.|..
 Worm   549 VREFFRIMGEPADRTNFLQSPAMVNAW--------YQPERNSITFPYAAWNPPY-YNLNYPQAYN 604

  Fly   507 YGTLGFTMAHEMAHGFDDLNRLYDSRGNLND-NWS------TQTKVGFELVKNCLADQFSGML-- 562
            :...|.|..||:.||:||....:...|.|.| :|:      |.:..||..:..|:..|||...
 Worm   605 FAGQGGTGGHELTHGYDDEGVQFGFNGELTDCSWNKCGWMDTNSSSGFIDMAQCVVTQFSTQCCP 669

  Fly   563 --YGNLRLRR-LKSQAESIADNVGIRIAQSAYWKWLDQVEM-EETESLPHM-TQSPEQLFFLSAA 622
              .||:.... ..:|.|:|||..|.:.|..:|.:::..... .|.:.||.: ..:|.|:|:::..
 Worm   670 EKTGNIHCANGATTQGENIADLGGQQAAYRSYRQYVATTRKGVEEDRLPGLENYTPNQIFWITYG 734

  Fly   623 QFMC---SDIYPERRANFVR---NNFHPPYEARVFAMMINSPAFAEAFQCSNSSKM--NPPNKCL 679
            ...|   ||      ||.|.   .|.|.|.:.|...:|.:.|.|.:.|.|...|.|  .|..:|.
 Worm   735 YSWCMKQSD------ANLVHQLLTNPHSPAQCRTNQVMQDIPEFGKDFGCVRGSPMYPEPSGRCK 793

  Fly   680 MY 681
            ::
 Worm   794 VW 795

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	PepO	49..672	CDD:226118	156/788 (20%)
		M13	55..678	CDD:189000	156/770 (20%)
nep-22	NP_509528.1	PepO	76..795	CDD:226118	158/780 (20%)
		M13	83..793	CDD:189000	156/771 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920