Protein Alignment Nepl17 and nep-21

DIOPT Version :9

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001360525.1
• Gene: nep-21 / 179925
• WormBaseID: WBGene00011794
• Length: 864
• Species: Caenorhabditis elegans
• Alignment Length: 713
• Identity: 171/713 - (23%)
• Similarity: 304/713 - (42%)
• Gaps: 119/713 - (16%)

  Fly    51 MDTSVSPCDDFYGYACGNYA-------------TINAATSQKDTNIRQLMFANYLRRVRQVLNEP 102
            :::.::||:|||.:|||||.             ||:...|:.:            ::|:.:|..|
 Worm   189 LNSKINPCEDFYEFACGNYGLNKNLPANKPLRHTISDVQSRLN------------KQVKSMLQSP 241

  Fly   103 RISTDRPMEVRVKYFYESCLDTAALRTKQRSHLLSVLREFGGMPAVEGKSWDYVGFDAIEMMAQL 167
            ..:.::|.:...|.:|:.|||...|.:.....:..:.:..||.|.:||..|........|.:|.:
 Worm   242 ISANEKPWDKVAKGYYQKCLDEEELESTGVEAMRDIAKRIGGWPTLEGDKWQEWSHSWEEQIALV 306

  Fly   168 LRRYG-KLTLLGVYVVPDHFNSQIKRLQL-------GQRLD-LAESDEFASLWKKYALKMRLRNL 223
            |...| ...:|.:.|..|..||....::|       |.|.. |:.:::  .:.:.|...|::..:
 Worm   307 LNLTGVNAVILEMAVTHDPSNSSRSVIELDQPKWGAGSRYPYLSGAND--PMLRNYTTLMKMTAV 369

  Fly   224 -LGLSEELARKTAEEIIELELELSRSAFDHRMNRDPRLMRHLTMLSNMSDAYGPILNVTRFVTS- 286
             ||....:|.|...|.:|.||:|...:.|..:.|||....:...|..:...: |.:|..:::.:
 Worm   370 ALGADPAIAEKEMNEAMEFELKLVNFSADDMVRRDPERGNNRFELWQLKSVF-PFINFEKYLKTV 433

  Fly   287 -----WLGSEYNLPVFESVPSYLFQVKKILLSTPNHVVANYMLSSLLTD---------------- 330
                 .|...:.:.|.|.  .|...::.:|.|||..|:|||:...|:..
 Worm   434 FKELVALSPNHTVIVREI--DYFVGIQHVLQSTPKRVLANYISWRLVQGGPTGDYFSFSPFLPPS 496

  Fly   331 -----FEITANEEQQKVICHERITELF----PD-----VVDHMVYHSLEQQNPYIAN-------- 373
                 ::..||:           |.:|    ||     |...::...:.....::.|
 Worm   497 AREPFYQFKANQ-----------TGMFNSPPPDRWEDCVTLSVIMMDMPVGRLFVENFFEKERAM 550

  Fly   374 -EMRSLWVELKSSFREMLSSPDIEWLEKQTREELLEKLNGMSFEIAGGQAVNF-----EEQFGDL 432
             :|..|...||:.|.:.|..  ::|:::.||...:.|.|.:.:: :|...|.|     |:.:| :
 Worm   551 KKMTELTSYLKNEFIKQLHV--LDWMDEITRRRAISKANMIEYK-SGFPMVLFNDTWMEKNWG-M 611

  Fly   433 VVSSADYYGNIQRLLEVKARILR--TDLLRESS----SVYYYHGVTATPIYETETNLVVLPVSYM 491
            ::...:|..:    |.::.:::|  .:|||...    |:::.........|....|.::.|...|
 Worm   612 IIKPREYLLH----LTIRVKLVRFTEELLRLDQPLDRSMWFQSPAQVDAYYAPNNNEMIFPAGIM 672

  Fly   492 QHRYLWDDIYPAALKYGTLGFTMAHEMAHGFDDLNRLYDSRGNLNDNWSTQTKVGFELVKNCLAD 556
            |..:|...: |..:.||.:|..:.||::|.|||....||..|||||.|..:|:..|.....|...
 Worm   673 QFPFLTLGV-PNYITYGMVGAVIGHEVSHAFDDQGGQYDEMGNLNDWWDAETEEKFIEKTRCFVR 736

  Fly   557 QFSG--MLYGNLRLRRLKSQAESIADNVGIRIAQSAYWKWLDQVEMEETESLPHMTQ-SPEQLFF 618
            |:..  ::..::.|....|..|:||||.|::.|.:||..|..........:||.... :.:|:||
 Worm   737 QYENVHVVEADIHLNGQLSLGENIADNGGVKTAFNAYKAWKSNTTGISEPALPGFQNFTSQQMFF 801

  Fly   619 LSAAQFMCSDIYPERRANFVRNNFHPPYEARVFAMMINSPAFAEAFQCSNSSKMNPPNKCLMY 681
            |:.|...||.:.|:.....:..:.|.|.:.|....:.|.|.||:||||...|.|||..||.::
 Worm   802 LAYANNWCSLVRPKHYIQIILTDVHAPSKYRAMIPLQNRPEFAKAFQCPIGSPMNPERKCQVW 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	PepO	49..672	CDD:226118	166/702 (24%)
		M13	55..678	CDD:189000	169/704 (24%)
nep-21	NP_001360525.1	M13	193..862	CDD:341056	170/705 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920