Protein Alignment Nepl17 and nep-23

DIOPT Version :9

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_503004.2
• Gene: nep-23 / 178472
• WormBaseID: WBGene00013785
• Length: 714
• Species: Caenorhabditis elegans
• Alignment Length: 743
• Identity: 160/743 - (21%)
• Similarity: 272/743 - (36%)
• Gaps: 212/743 - (28%)

  Fly    41 IAKSAEMCSFMDTSVSPCDDFYGYACG--NYATINAATSQKDTNIRQLMFANYLRRVRQVLNEPR 103
            |..:.::.::.|.|..|||:||...||  :..::.:..::|...:|.|        :|:.:...:
 Worm    82 ITLAHQLHNYHDPSADPCDNFYQSVCGKQHEHSLKSGLAKKHLILRNL--------IRETITNRK 138

  Fly   104 ISTDRPMEVRVKYFYESC-----------LDTAALRTKQRSHLLSVLREFGGMPAVEGKSWDYVG 157
            ::.....|..::.|:..|           :...|||...|.     ::..|..|| ..::|:...
 Worm   139 VTPTSKSENEMRKFHGICSKYQRANSSSDIAQQALRDIFRD-----VQSIGSWPA-GSRNWNESD 197

  Fly   158 FDAIEMMAQLL----------------------------RRYGKL--TLLGVY----VVPDHFNS 188
            |:..||:..|:                            |.|.||  |:|.::    :|||
 Worm   198 FNLNEMLNNLVKLGQRNFGLFQISFKYRDQLLISAEEHRRNYSKLEPTILNIFETNGLVPD---- 258

  Fly   189 QIKRLQLGQRLDLAESDEFASLWKKYALKMRLRNLLGLSEELARKTAEEIIELELELSRSAFDHR 253
               |:||     |.:.:.||||
 Worm   259 ---RIQL-----LKDLEGFASL------------------------------------------- 272

  Fly   254 MNRDPRLMRHLTMLSNMS-------DAYGPILNVTRFVTSWL--GSEYNLPVFESVPSYLFQ--- 306
                ..|:::...|.||.       |...|.::....|.:.:  |.|:.:|..|...|.|.|
 Worm   273 ----EALLKNHYYLDNMDKMKPAVLDDLVPSVDFMGLVKAMISPGKEHLMPKIELKTSVLNQTLF 333

  Fly   307 ------VKKILLSTPNHVVANYMLSSLLTD------FEITANEEQQKVICHERITELFPDVVDHM 359
                  ::.|:|.||...:|||::.:.:..      ||.|:   |:...|.:::....|.....:
 Worm   334 NDENMNLEAIILDTPKRTLANYLIFNFIDSSLDHLVFETTS---QKGNTCEDKVITYLPRASLRV 395

  Fly   360 VYHSLEQQNPYIANEMRSLWVELKSSFREMLSS--PDIEWLEKQTREELLEKLNGMS-------- 414
            ...:      |:..|.|.|..:|....|..|.:  .:..||:.::::..|:|:|.|.
 Worm   396 FIRN------YVDKENRDLITQLAEKTRIALHTLVQNSTWLKAESKQLALDKINAMGKMIGYPDF 454

  Fly   415 FEIAGGQAVNFEEQFGDLVVSSAD-YYGNIQRL----LEVKARI------LRTDL-LRESSSVYY 467
            ||..|    ..:..|.:|.:.|:| ||..:.:|    :|.|...      |..|| :.|.::.||
 Worm   455 FEPPG----TLDGMFKNLNLDSSDTYYTALNKLERYFVEQKMDYFAEETPLDPDLRVFEMNAYYY 515

  Fly   468 YHGVT---ATPIYETETNLVVLPVSYMQHRYLWDDIYPAALKYGTLGFTMAHEMAHGFDDLNRLY 529
            ..|..   ..|.::..               ::|..||..:.....|..:.|||.|.|.....|.
 Worm   516 IPGNQLNFLAPFFDDP---------------MFDSTYPDYVNIAMSGNIIGHEMGHAFGPHAILR 565

  Fly   530 DSRGNLNDNWSTQTKVG-FELVKNCLADQFSGMLYGNLRLRRL----KSQAESIADNVGIRIAQS 589
            ..||  .:.|....::. :|....|||:|:|.  |.:....|:    |...|.:|||:|..::
 Worm   566 TVRG--REVWMKPEELAEYESRAQCLANQYSE--YDDPDFGRVFDGGKVIDELVADNIGREVS-- 624

  Fly   590 AYWKWLDQVEM-EETESLPHMTQSPEQLFFLSAAQFMCSDIYPERRANFVRNNFHPPYEARVFAM 653
              ||....::: ..|..:.......:||:|...|...|:. :..|.......:.||....||..:
 Worm   625 --WKMFKSLDLTNATRIIGFEDYDIDQLYFRVGALTHCTP-HAMRDLKGSIESSHPRKAFRVNGV 686

  Fly   654 MINSPAFAEAFQCSNSSKMNPPNKCLMY 681
            ..|.|.||.||.|...|.|||..||.|:
 Worm   687 YANLPEFARAFNCPTGSPMNPRKKCDMF 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	PepO	49..672	CDD:226118	153/724 (21%)
		M13	55..678	CDD:189000	154/724 (21%)
nep-23	NP_503004.2	M13	96..711	CDD:189000	154/724 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920