Protein Alignment Nepl17 and nep-11

DIOPT Version :10

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_494538.1
• Gene: nep-11 / 173685
• WormBaseID: WBGene00017557
• Length: 848
• Species: Caenorhabditis elegans
• Alignment Length: 745
• Identity: 184/745 - (24%)
• Similarity: 309/745 - (41%)
• Gaps: 158/745 - (21%)

  Fly    43 KSAEMCS-------------FMDTSVSPCDDFYGYACGNYATINAATSQKDTNIRQLMFANYLRR 94
            |..|:||             .|:|||.|||||:.:|||.:   |......|.......||....:
 Worm   156 KEPEVCSTPGCVRAATHFLNAMNTSVDPCDDFFEFACGQW---NDQHPIPDDMYGFGTFAYAREQ 217

  Fly    95 VRQ---VLNEPRISTDRPMEVRVKYFYESCLDTAALRTKQRSHLLSVLREFGGMPAVEGKSWDYV 156
            |||   ||.|..:.|:.......:..|.||::...|.......|...|.|.|..|.:: ::||..
 Worm   218 VRQQLRVLLEQEVVTESESINMARATYRSCMNKTQLDELMTGPLFETLTELGEWPLLQ-ENWDKT 281

  Fly   157 GFDAIEMMAQLLRRYGKLTLLGVYVVPDHFNSQIKRLQLGQR------------LDLAESDEFAS 209
            .|:...::....|.||......:|:..|..|:....|.:.|.            |:........:
 Worm   282 KFNFTSLLVNSRRDYGVDVFFQLYIYADSKNTSRNTLFIDQSTLALGRGTRDYYLNTTLFSSHMT 346

  Fly   210 LWKKYALKMRLRNLLGLSEELARKTA------EEIIELELELSR--SAFDHRMNRDPRLMRHLTM 266
            .::||.  .::.:||.....|.|..:      |:||:.|:||::  .|.|.|.|.        |.
 Worm   347 AYRKYL--RQIAHLLKTDGNLTRSESEMNADIEKIIDFEIELAKIIVAEDERRNN--------TR 401

  Fly   267 LSN---MSDAYGPILNVTRFVTSWLGSEYNLPVFESV-PS------------------YLFQVKK 309
            |.|   :.|.|..:..|     .|      :|.|:|: ||                  ||..|.:
 Worm   402 LYNKRQIQDLYNLLPQV-----DW------VPFFQSIAPSDLTHLFHNETEIIICEIEYLQHVSE 455

  Fly   310 ILLSTPNHVVANYMLSSLLTDFEITANEEQQKVICHERITELFPDV-VDHMVYHSLEQQNP---- 369
            ::..|...::.||:|..::          |..|   ..:.|.|.|: .|.:...:.:||:|
 Worm   456 LIEKTDVGLLTNYVLWRVV----------QSNV---RYLDERFEDIKQDFLKVMTGQQQSPPRWK 507

  Fly   370 -----------------YI--------ANEMRSLWVELKSSFREMLSSPDIEWLEKQTREELLEK 409
                             |:        .:|...:.:.|::||.:::...|  |::::|:...:||
 Worm   508 DCAQVPSTVLPLAAGAIYVQAHFQESDKHEALRMIMHLRNSFADLVRQND--WMDEETKAVAIEK 570

  Fly   410 LNGMSFEIAGGQAVN----FEEQFGDLVVSSADYYGNIQRLLEVKARI-LRTDLLRESSSVYYYH 469
            .|.|...|......|    .::|:..|.:|.:|.|..|.:    |:.: :::...::.:..:..|
 Worm   571 ANSMINNIGYPDVTNDLPKLDKQYLGLSISDSDTYYYIMK----KSVVWMQSREFQKLTKPFDKH 631

  Fly   470 GVTATP-----IYETETNLVVLPVSYMQHRYLWDDIYPAALKYGTLGFTMAHEMAHGFDDLNRLY 529
            ....:|     .|..|.|.:..|...:|..: :...:|.|:.||.:|..:.||:.|||||....|
 Worm   632 EFDISPAVVNAFYSPEKNAITFPAGILQPPF-FSGTFPKAVNYGAIGAVIGHEITHGFDDQGSQY 695

  Fly   530 DSRGNLNDNWSTQTKVGFELVKNCLADQFSGMLYG-------NLRLRRLKSQAESIADNVGIRIA 587
            |..|||::.||..:...|:..:.|:.:|     ||       |.|:....:|.|:||||.|::.|
 Worm   696 DKDGNLHNWWSESSLNSFDTRRRCIVEQ-----YGNYTVPKTNFRVNGKLTQGENIADNGGVKEA 755

  Fly   588 QSAYWKWLDQVEMEETESLPHMTQ-SPEQLFFLSAAQFMCSDIYPERRANFVRNNFHPPYEARVF 651
            ..||.|::  .|..|...||.:.| :.||:||:|.|.|.|...........|..:.|.|...||.
 Worm   756 FQAYQKYV--TENGEEPRLPGLQQYTNEQIFFVSYAHFWCGKKKEAAAMQQVLTDEHSPEVFRVI 818

  Fly   652 AMMINSPAFAEAFQCSNSSKMNPPNKCLMY 681
            .::.|..|||:.::|..::.:||.:||:::
 Worm   819 GVLSNMQAFADVYKCPRNAPVNPDHKCIVW 848

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	M13	55..678	CDD:341056	175/715 (24%)
nep-11	NP_494538.1	M13	181..845	CDD:341056	175/715 (24%)