Protein Alignment Nepl17 and nep-9

DIOPT Version :10

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_494531.2
• Gene: nep-9 / 173683
• WormBaseID: WBGene00017554
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 710
• Identity: 150/710 - (21%)
• Similarity: 281/710 - (39%)
• Gaps: 148/710 - (20%)

  Fly    41 IAKSAEMCSFMDTSVSPCDDFYGYACGNYATINAATSQKDTNIRQLMFANYLRRVRQVLNEPRIS 105
            |..:.|:.::.||:...|:|||...|.||....|....:|...|:.:  |.|  ||..|.....:
 Worm    70 IILAQELKAYSDTATKSCEDFYKATCENYKDHQALDRHRDCKKRKAV--NKL--VRGFLQRDEST 130

  Fly   106 TDRPMEVRVKYFYESCLDTAALRTKQRSHLLSVLREFGGMPAVEGKSWDYVGFDAIEMMAQLLR- 169
            .....|..:|..:..|.:.:  |......:...:::.|..|.:| .:|....|:..:::|:|::
 Worm   131 FTSESESAIKLIFGKCDELS--RNTSYLDIFKDIKKIGSWPVLE-HNWKDSMFNLDDVIAKLVKL 192

  Fly   170 ---RYG--KLTL-------LGVYVVPDHFNS--QIKRLQLG-----------QRL--DLAESDEF 207
               .:|  ||.|       ..|:|......:  |:::..||           :.|  ||.:..:|
 Worm   193 GSTDFGLFKLELRKLAFGHFAVFVSSKQEQNIHQLEKTILGILKANGIQQDRKELSDDLKDYSDF 257

  Fly   208 ASLWKKY-----ALKMRL------RNL--LGLSEELARKTAEEIIELELELSRSAFDHRMNRDPR 259
            .:..|::     .::.||      .||  ..|:.::|.|:.          ....|:|...|
 Worm   258 KNHLKEFYQEETYIEYRLYAGSIVENLGISSLTTQMALKST----------GLDVFNHVNQR--- 309

  Fly   260 LMRHLTMLSNMSDAYGPILNVTRFVTSWLGSEYNLPVFESVPSYLFQVKKILLSTPNHVVANYM- 323
                 |:::|.|              .:.|.|.||.:             |:..||...:||::
 Worm   310 -----TLITNSS--------------LFFGEENNLGM-------------IIQKTPKRTLANFLI 342

  Fly   324 ---LSSLLTDFEITANEEQQKVICHERITELFPDVVDHMVYHSLEQQNPYIANEMRSLWVELKSS 385
               :..:.||.   ||..:   .|.|.:.:|.|.....::..:...::  ..::|..:..:||:.
 Worm   343 FHFIDVMTTDL---ANATK---ACKETLIDLLPRASIQVLSRNFVNED--AQDDMVKMAQDLKTK 399

  Fly   386 FREML-SSPDIE----WLEKQTREELLEKLNGMSFEIAGGQAVNFEEQFGDLVVSSAD-YYGNIQ 444
            ..||: :||...    ..:.:.:::|::|:..:.......|.| .:..|..|.::.:| .|..||
 Worm   400 ITEMIDNSPFFTKFHLVFDAEEQKKLIQKVKAIGIVTEYPQEV-LDRDFERLNLTPSDSIYRTIQ 463

  Fly   445 RLLEVKARILRTDLLRESSSVYYYHG--------VTATPIYETETNLVVLPVSYMQHRYLWDDIY 501
            :|     |.||::.|.|     :..|        |..:..|:..||.:.:....:...| :|..|
 Worm   464 KL-----RRLRSEQLIE-----HLGGDLDPTDTRVWGSAHYDQTTNNLTIFAPIIDGPY-FDTSY 517

  Fly   502 PAALKYGTLGFTMAHEMAHGFDDLNRLYDSRGNLNDNW-STQTKVGFELVKNCLADQF----SGM 561
            |..:....:||.:..|:....|.:....|.:|. .:|| ..::...|:....|.|:::    ..:
 Worm   518 PNYVNQFLMGFILGRELGRSLDSVRIRKDEKGQ-TENWLKPESLKRFDEHLKCWAEKYDKSADPL 581

  Fly   562 LYGNLRLRRLKS---QAESIADNVGIRIAQSAYWKWLDQVEMEETESL-PHMTQSPEQLFFLSAA 622
            ...:..:|:::.   |.|..||.:|    ..|.|:...:::::..|.| ........::||...|
 Worm   582 KSESKGIRQIEGRYIQNEMFADFIG----HEASWRAFMKLDVKNEEVLETFKVIKLRRMFFNVQA 642

  Fly   623 QFMCSDIYPERRANFVR-NNFHPPYEARVFAMMINSPAFAEAFQCSNSSKMNPPNKCLMY 681
            .:.|..  |....:::. ...|..|..||.....|.|.||.||:|::...|||.|||.|:
 Worm   643 LYFCRP--PSGSTDWLSYQEHHQHYSFRVNGAFKNMPQFALAFECASDDDMNPQNKCSMF 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	M13	55..678	CDD:341056	143/691 (21%)
nep-9	NP_494531.2	GluZincin	87..698	CDD:472708	144/689 (21%)