Protein Alignment Nepl17 and Nep2

DIOPT Version :10

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: XP_061497288.1
• Gene: Nep2 / 1281326
• VectorBaseID: AGAMI1_002834
• Length: 792
• Species: Anopheles gambiae
• Alignment Length: 711
• Identity: 177/711 - (24%)
• Similarity: 295/711 - (41%)
• Gaps: 131/711 - (18%)

  Fly    51 MDTSVSPCDDFYGYACGNYATINAATSQK-DTNIRQLMFANYLRRVRQVLNEPRISTDRPMEVRV 114
            ||..|.||||||.||||.:........:| ..|...::.....:::|.:::|....::.......
Mosquito   127 MDQEVEPCDDFYNYACGKFVKETVIPDEKVSVNTFSVIGDRLQQQLRSLVSEEISDSEATPFKLA 191

  Fly   115 KYFYESCLDTAALRTKQRSHLLSVLREFGGMPAVEGKSWDYVGFDAIEMMAQLLRRYGKLTLLGV 179
            |..|:.|::...:..|....||.:....||.|.::|.|||.....:.....:..|..|..|
Mosquito   192 KNLYKLCMNKTRIEEKGIKPLLDIHEVLGGWPVLKGDSWDLDSSWSWVKSVKDFRNNGYST---- 252

  Fly   180 YVVPDHF---------NSQIKRLQLGQRLDLAESDEF---------ASLWKKYALKMRLRNLLGL 226
                |:|         .:..:|:....:..|..|.|:         .|.:..|.:.|.:  |||.
Mosquito   253 ----DYFFDFSIGSDLKNSTRRIIDTDQASLGISREYLVKGMENPIVSAYYNYMVDMAV--LLGA 311

  Fly   227 SEELARKTAEEIIELELELSRSAFDHRMNRDPRLMRHLTMLSNMSDAYGPILNVTRF-----VTS 286
            .||.|::...:.:..|:.|:..:..:...|            |.:..|.| :.|..|     .|.
Mosquito   312 DEERAKRELLDSLNFEMALANISLPNEKRR------------NATALYNP-MTVKEFQQRYPYTD 363

  Fly   287 WL--------------GSEYNLPVFESVPSYLFQVKKILLSTPNHVVANYML-------SSLLTD 330
            ||              |.|..:.|  |||:::.|:..:|.:||..|:|||::       |..||:
Mosquito   364 WLEYFNAILKDTGIVIGEEEVIIV--SVPTFMEQLGPLLQNTPKRVMANYVMWRISGFSSFFLTE 426

  Fly   331 ----------FEITANEEQQK--VICHERITELFPDVVDHMVYHSLEQQNPY-----IANEMRSL 378
                      ..::..:||:.  ..|.:..:...|..|..:......:::..     :.|:::|:
Mosquito   427 KLRKRQLQYSTALSGKQEQEPRWKECVDITSGSLPISVGALYIRKYFREDSKRAALDMVNDIKSV 491

  Fly   379 WVELKSSFREMLSSPDIEWLEKQTREELLEKLNGMSFEIAGGQAV----NFEEQFGDL------- 432
            :|::...         ::|:::.||...|||::.|:..|.....:    ...|.:.||
Mosquito   492 FVDILKK---------VDWMDEVTRVSALEKVSTMATHIGYPDELMDDAKIAEYYKDLEFQPDST 547

  Fly   433 ---VVSSADYYGNIQRLLEVKARILRTDLLRESSSVYYYHGVTATPIYETETNLVVLPVSYMQHR 494
               .:...:.:|..:...:::..:.:||.:..|      ........|.:..|.:..|...:|.:
Mosquito   548 YLNTILYMNKFGTTKAFKKLRIAVNKTDWITHS------RPAIVNAFYSSIENSIQFPAGILQGQ 606

  Fly   495 YLWDDIYPAALKYGTLGFTMAHEMAHGFDDLNRLYDSRGNLNDNWSTQTKVGFELVKNCLADQFS 559
            :...| .|..:.||.:||.:.||:.|||||..|.:|..|||.|.|.:.||..:.....|:.:|
Mosquito   607 FFSYD-RPKYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDWWQSDTKTAYLEKARCIIEQ-- 668

  Fly   560 GMLYGN-------LRLRRLKSQAESIADNVGIRIAQSAYWKWLDQVEMEETESLPHMTQSPEQLF 617
               |||       |.|..:.:|.|:||||.||:.|..||.:|.::...|  :.||.:..||||:|
Mosquito   669 ---YGNYTEPNVKLNLNGINTQGENIADNGGIKEAYYAYRRWTEKNGPE--QRLPGLNLSPEQMF 728

  Fly   618 FLSAAQFMCSDIYPERRANFVRNNFHPPYEARVFAMMINSPAFAEAFQCSNSSKMNPPNKC 678
            :|||||..||...||.....:....|.|.:.||...|.|...||:.|.|...|.|||.:||
Mosquito   729 WLSAAQTWCSVYRPETMKMRITTGVHSPGQFRVLGPMSNMHEFAKDFNCPVGSPMNPEHKC 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	M13	55..678	CDD:341056	173/705 (25%)
Nep2	XP_061497288.1	None