Protein Alignment Nepl17 and Nep1

DIOPT Version :10

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: XP_553645.4
• Gene: Nep1 / 1279203
• VectorBaseID: AGAMI1_011171
• Length: 869
• Species: Anopheles gambiae
• Alignment Length: 710
• Identity: 180/710 - (25%)
• Similarity: 315/710 - (44%)
• Gaps: 98/710 - (13%)

  Fly    34 LGQQIMRIAKSAEMCSFMDTSVSPCDDFYGYACGNYATINAATSQKDTNIRQLMFANYLRRV-RQ 97
            |..:.:|.|.|  :.:.||.:..||.||:.:|||.:..::.....:.:.....:.|:..:.: :.
Mosquito   196 LTDECVRTASS--LLAAMDRTADPCKDFFQFACGTWNKMHVIPEDRSSISTFEVLADQQQAILKG 258

  Fly    98 VLNEPRISTDRPMEVRVKYFYESCLDTAALRTKQRSHLLSVLREFGGMPAVEGKSWDYVGFDAIE 162
            ||.||....|.....:.|.||:||::...:|......|...|::.||.|.:| |:|.........
Mosquito   259 VLEEPVNKEDNRATKKAKAFYKSCMNLEQIRLLDVQALRKSLKKLGGWPVIE-KNWTVPSTSIEH 322

  Fly   163 MMAQLLRRYGKLTLLGVYVVPDHFNSQIKRLQLGQRL--------DLAESDE-FASLWKKYALKM 218
            ::.:|...|.:..|:.:||..|..||.:..:|:.|.|        .|.||.| ....:.:|..::
Mosquito   323 LLGKLTGEYDEPGLVELYVGADDKNSSMNIIQVDQLLLALPSRDYYLKESSEGDMKAYHRYMTQI 387

  Fly   219 RLRNLLGLSEELARKTAEEIIELELELSRSAFDHRMNRD----------PRLMRHLTMLSNMSDA 273
            .:  |:|..::.|.:..:.|:|.|:.|:.:........|          |.|.|.:
Mosquito   388 AI--LMGADKDKAAEELQRIVEFEVRLANATLPEADRHDTSAIYTKITLPELQRRV--------- 441

  Fly   274 YGPILNVTRFVTSWLGS----------EYNLPVFESVPSYLFQVKKILLSTPNHVVANY------ 322
              |.:|...::.:.||:          .|.:|       ||.::.|||..|...:|.||
Mosquito   442 --PQINWKEYLQTTLGTVALHPNESIVSYAMP-------YLVELGKILRDTDRRIVHNYAIWRLV 497

  Fly   323 --MLSSLLTDFEITANEEQQKVI-----------CHERITELFPDVVDHM-VYHSLEQQNPYIAN 373
              :::.::.|::....|.::|::           |.|...:.....|..: :..:..|::...|.
Mosquito   498 MSIMTHMIDDYQKERVEFRRKLLGIQSERNRWSQCVEWTNKKLGMAVGALFIRDNFNQESKETAL 562

  Fly   374 EMRSLWVELKSSFREMLSSPDIEWLEKQTREELLEKLNGMSFEIAG----GQAVNFEEQFGDLVV 434
            .|..   .::.:|.|:|:  ||:|::.:||....||.:.|:..|..    ..|...|:::.:|.:
Mosquito   563 TMIH---TIREAFNELLA--DIDWMDDETRAVAKEKADAMNERIGYPDILTNADELEKEYVNLTI 622

  Fly   435 SSADYYGNIQRLLEVKARILRTDLLRE--SSSVYYYHGVTATPIYETETNLVVLPVSYMQHRYLW 497
            ....:..||..:|:.:|. ....|||:  ..:.:..........|....|.:|.|...:|..: :
Mosquito   623 HGGLFLENILSILKWEAE-RNLQLLRKPVDKNKWATEPAVVNAFYNPNKNDIVFPAGILQPLF-Y 685

  Fly   498 DDIYPAALKYGTLGFTMAHEMAHGFDDLNRLYDSRGNLNDNWSTQTKVGFELVKNCLADQFSGM- 561
            ...:|.:|.||.:|..:.||:.|||||..|.:|..||:...|:..|...|.....|:.||:|..
Mosquito   686 SQNFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKDGNMMQWWNNATIKTFRERAQCIIDQYSRYK 750

  Fly   562 -----LYGNLRLRRLKSQAESIADNVGIRIAQSAYWKWLDQVEMEETESLPHMTQSPEQLFFLSA 621
                 ||.:.|:    :|.|:||||.|::.:..||.||:.|...|  ..||.:..:.:|||||:.
Mosquito   751 IDEVGLYMDGRM----TQGENIADNGGLKQSYRAYRKWVSQHGSE--PDLPGLNMTHDQLFFLNY 809

  Fly   622 AQFMCSDIYPERRANFVRNNFHPPYEARVFAMMINSPAFAEAFQCSNSSKMNPPNKCLMY 681
            ||..|..:.||.....:|::.|.|...||...:.||..||||::|...|.|||.:||.::
Mosquito   810 AQIWCGSMRPEDALTKIRSSVHSPGIIRVIGPLSNSRDFAEAYRCPLGSPMNPVSKCSVW 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	M13	55..678	CDD:341056	172/684 (25%)
Nep1	XP_553645.4	None