Protein Alignment Nepl17 and Nep3

DIOPT Version :10

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: XP_317711.2
• Gene: Nep3 / 1278166
• VectorBaseID: AGAMI1_011685
• Length: 789
• Species: Anopheles gambiae
• Alignment Length: 723
• Identity: 183/723 - (25%)
• Similarity: 297/723 - (41%)
• Gaps: 124/723 - (17%)

  Fly    41 IAKSAEMCSFMDTSVSPCDDFYGYACGNYATINAATSQKD--------TNIRQLMFANYLRRVRQ 97
            |..::|:...:|.||.||||||.::|..:...|.....|.        ....||:..|.|.|
Mosquito   109 IFAASEILHSIDWSVDPCDDFYAFSCNQWIRNNPIPEGKSMWGLFGKLEQQNQLVLKNALER--- 170

  Fly    98 VLNEPRISTDRPMEVRVKYFYESCLDTAALRTKQRSH-LLSVLREFGGMPAVEGKSWDYVGFD-- 159
                |........|.:.|.:|:||||......|..:. |..:||:.||.......|    |||
Mosquito   171 ----PLAEFKSKAEKKAKLYYQSCLDEDETMEKLGAEPLQKLLRQIGGWNVTANAS----GFDVQ 227

  Fly   160 --AIEMMAQLLR-RYGKLTLLGVYVVPDHFNSQIKRLQLGQ-RLDLAESDEF---------ASLW 211
              :::...|.|: ||....|.|..|..|..||....:|:.| .|.|...|.:         .:.:
Mosquito   228 RWSLQRTLQTLQIRYNMGGLFGWAVGEDDRNSSKHIIQIDQGGLTLPSRDNYLNKTANAKILTAY 292

  Fly   212 KKYALKMRLRNLLGLSEELARKTAEEIIELELELSRSAFDHRMNRDPRLMRHLTMLSNMSDAYGP 276
            .:|..|:.:  |||..|..||:...|:||.|..|:.......|.||...:.|...|:.:.:. .|
Mosquito   293 LEYMTKVSV--LLGADETDARRQMLEVIEFETRLANITTPQDMRRDEETLYHPMTLAMLQEK-AP 354

  Fly   277 ILN-------VTRFVTSWLGSEYNLPVFESVPSYLFQV------------KKILLSTPNHVVANY 322
            .:|       ..|.|...:..:..:.|:  .|.||.::            |||:|:       ||
Mosquito   355 FINWQEHFEEAFRLVRRKITEKERVVVY--APEYLEKLNILMKEYTSTDEKKIILN-------NY 410

  Fly   323 M-------LSSLLTDFEITANEEQQKVI------------CHERITELFPDVVDHM----VYHSL 364
            :       |::.|:.....|.:..:|.:            |....:.:....|..|    |:|.
Mosquito   411 LVWQTVRTLTACLSKAFRDAYKGLRKALMGSDGGEELWRYCVSDTSNVLGFAVGAMFVRDVFHG- 474

  Fly   365 EQQNPYIANEMRSLWVELKSSFREMLSSPDIEWLEKQTREELLEKLNGMSFEIAGGQAVNFEEQ- 428
             ...|. |.||.:   :::.:|:|  :..::.|::.:||...:||.:.:|..|.....:.:.|:
Mosquito   475 -DSKPQ-AEEMIN---QVRDAFKE--NFKNLGWMDAETRRLAVEKADAISDMIGFPDYILYPEEL 532

  Fly   429 ---FGDLVVSSADYYGN--IQRLLEVKARILRTDLLRESSSVYYYHGVTATPI--YETET-NLVV 485
               :.||.:....|:.|  ...:..:|..:.:.|.....:.    .|:|...:  |.|.| |.:|
Mosquito   533 DRKYQDLNIDPKTYFDNNINYNIYSLKKNLEKLDQPVNKTK----WGMTPPTVNAYYTPTKNQIV 593

  Fly   486 LPVSYMQHRYLWDDIYPAALKYGTLGFTMAHEMAHGFDDLNRLYDSRGNLNDNWSTQTKVGFELV 550
            .|...:|:.: :|.....:|.||.:|..|.||:.|.|||..|.||..|||:..|:.||...|:..
Mosquito   594 FPAGILQNPF-FDIKNSKSLNYGAMGVVMGHELTHAFDDQGREYDKYGNLHQWWNNQTIERFKNQ 657

  Fly   551 KNCLADQFSGMLYGNLRLRRLKSQAESIADNVGIRIAQSAYWKWLDQVEME-------ETESLPH 608
            ..|...|:|........:...::..|:||||.|::.|..||      :..|       :|..||.
Mosquito   658 TECFNQQYSAYRINGKTINGKQTMGENIADNGGLKAAFHAY------INNEKNSYTDTDTLPLPG 716

  Fly   609 MTQSPEQLFFLSAAQFMCSDIYPERRANFVRNNFHPPYEARVFAMMINSPAFAEAFQCSNSSKMN 673
            :..:..||||:|.||..||.:..|.....:..:.|.|.:.||...:.|...|::.|.|...:.||
Mosquito   717 VNMTHRQLFFVSFAQVWCSAVTDETTTLQIEKDSHSPPKYRVIGPLSNLKEFSDTFHCPLGTGMN 781

  Fly   674 PPNKCLMY 681
            |..||:::
Mosquito   782 PIEKCVVW 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	M13	55..678	CDD:341056	177/704 (25%)
Nep3	XP_317711.2	None