Protein Alignment Nepl17 and ecel1

DIOPT Version :10

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: XP_012818808.2
• Gene: ecel1 / 100496473
• XenbaseID: XB-GENE-989944
• Length: 764
• Species: Xenopus tropicalis
• Alignment Length: 759
• Identity: 189/759 - (24%)
• Similarity: 321/759 - (42%)
• Gaps: 136/759 - (17%)

  Fly     9 CLIF-VTLAVGSLAIQGG--VFKELTTPLGQQIMRIAKSAEMCSFM----------DTSVSPCDD 60
            ||:. :..|||...|.|.  |.|.|:  :.|.:..:....|..:||          |.::|||.|
 Frog    56 CLLSGLVFAVGLCVILGCMLVLKYLS--MEQDVQCLEGCQERKAFMRASKFITNNIDPTISPCTD 118

  Fly    61 FYGYACGN-------------YATINAATSQKDTNIRQLMFANYLRRVRQVLNEPRISTDRPMEV 112
            ||.:|||.             |.||.|...|.:..:..|:    |:.||:   :.:.|.:|
 Frog   119 FYSFACGGWLRRHGIPEDKLIYGTIAAIGEQNEEKLEHLL----LQPVRR---KHKGSAER---- 172

  Fly   113 RVKYFYESCLDTAALRTKQRSHLLSVLREFGG--MPAVEGKSWDYVGFDAIEMMAQLLRRYGKLT 175
            :||.|::|||:...:.......:|.|:.:.||  :|......||:     .|::.:....|....
 Frog   173 KVKEFFKSCLNMRDIDRLGARPMLQVIEDCGGWDLPEDPRTQWDF-----NELLYKTQGVYSTAV 232

  Fly   176 LLGVYVVPDHFNSQIKRLQLGQ--------RLDLAESDEFASLWKKYALKMR-LRNLLGLSEELA 231
            ...:.|..|..||....:::.|        .|.|.:.:|...:.:.|.:.|: :.:|||:  |..
 Frog   233 FFSMTVSLDDKNSSRYIIRIDQDGLTLPERTLYLGQDEESIKVLEAYKVFMQTILSLLGV--ENV 295

  Fly   232 RKTAEEIIELELELSR---SAFDHRMNRDPRLMRHLTMLSNMSDAYGPILNVTRFVTSWLGSEYN 293
            :|.||||:.||..||.   |.||. |.||...|.:...|:.:.. ..|.||....:.....:  |
 Frog   296 QKKAEEILHLEQHLSNITISEFDD-MRRDISTMYNKVTLAQLQQ-ITPHLNWKNLLNRIFHT--N 356

  Fly   294 LPVFESV----PSYLFQVKKILLSTPNHVVANYMLSSLLTDFEITANEEQQKVICHERITELFPD 354
            .|..|.|    ..|:.:|.:::.|||..|:.||||..::             |:..|.::..|.|
 Frog   357 FPEDEEVVVLATDYMQKVSEMIRSTPASVLHNYMLWRIV-------------VVLSEHLSTPFRD 408

  Fly   355 VVDHMVYHSLE--------------QQNPYIANEMRSLWVE------LKSSFREMLSS------- 392
            .: |.:...:|              |.|.:....:.:|:||      .|:..::::.:
 Frog   409 AI-HELSKEMEGSEKQAELTKVCLTQANKHFGMALGALFVEEYFSSSSKAKVQQLVENIKHILDY 472

  Fly   393 --PDIEWLEKQTREELLEKLNGMSFEIAGG----QAVNFEEQFGDLVVSSADYYGN----IQRLL 447
              .:::|::.:|::...|||..|...|...    |..:.:::: :..|:...|:.|    |:..:
 Frog   473 RLEELDWMDTETKQAAREKLKHMMVMIGYPDVLLQPESMDKEY-EFEVNEKTYFKNILNSIRYSI 536

  Fly   448 EVKARILRTDLLRESSSVYYYHGVTATPIYETETNLVVLPVSYMQHRYLWDDIYPAALKYGTLGF 512
            ::..|.:|.::   ..|.:..........|....|.:|.|...:|.. |:|..:|.:|.||.:|.
 Frog   537 KMAVRRIRQEV---DKSAWLLPPQALNAYYLPNKNQMVFPAGILQPT-LYDPDFPQSLNYGGIGT 597

  Fly   513 TMAHEMAHGFDDLNRLYDSRGNLNDNWSTQTKVGFELVKNCLADQFSGMLYGNLRLRRLKSQAES 577
            .:.||:.||:||....||:.||....|:..:...|.....|:.|.:......|.|:....:..|:
 Frog   598 IIGHELTHGYDDWGGQYDANGNPIQWWTEDSYSKFLKKAECIVDLYENFTVYNQRVNGRTTLGEN 662

  Fly   578 IADNVGIRIAQSAYWKWLDQVEMEETESLPHMTQSPEQLFFLSAAQFMC-----SDIYPERRANF 637
            |||..|:::|..||.||:.....|  ..||.:..:.:||||::.||..|     ..||.:
 Frog   663 IADLGGLKLAYYAYQKWVRDNGPE--RPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQ----- 720

  Fly   638 VRNNFHPPYEARVFAMMINSPAFAEAFQCSNSSKMNPPNKCLMY 681
            |..:.|.|...||...:.....|...|.|..:|.|||.:||.::
 Frog   721 VLTDKHAPEHYRVMGSVSQFEEFGRVFHCPRNSPMNPVHKCSVW 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	M13	55..678	CDD:341056	172/695 (25%)
ecel1	XP_012818808.2	M13	113..762	CDD:341056	173/696 (25%)