Protein Alignment Nepl17 and ecel1

DIOPT Version :10

• Sequence 1: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001429584.1
• Gene: ecel1 / 100332538
• ZFINID: ZDB-GENE-130530-692
• Length: 808
• Species: Danio rerio
• Alignment Length: 727
• Identity: 171/727 - (23%)
• Similarity: 292/727 - (40%)
• Gaps: 128/727 - (17%)

  Fly    36 QQIMRIAKSAEMCSFMDTSVSPCDDFYGYACG-------------NYATINAATSQKDTNIRQLM 87
            :.::|.|:..:  ..:|.||.||.|||.:|||             :|..|.|...|....:::|:
Zfish   129 RSLLRAARFVQ--GNIDPSVQPCHDFYSFACGGWLRRHGIPEDKLSYGIITAIGEQNQDKLQRLL 191

  Fly    88 FANYLRRVRQVLNEPRISTDRPMEVRVKYFYESCLDTAALRTKQRSHLLSVLREFGGM------P 146
            .|...||..:       |.:|    :||.||.||::...:.......:..|:...||.      |
Zfish   192 QAPVQRRELE-------SAER----KVKEFYRSCINIKEIDRLGAGPMTEVIDSCGGWDLSGAPP 245

  Fly   147 AVEGKSWDY----VGFDAIEMMAQLLRRYGKLTLLGVYVVPDHFNSQIKRLQLGQR--------L 199
            .  |..||.    :..|..||:.:....|.......:.|..|..||....:::.|.        |
Zfish   246 G--GAGWDSGSAPIRPDFNEMLYKTQGVYSTSVFFSLTVSVDDKNSSRNAIRIDQEGLTLPERTL 308

  Fly   200 DLAESDEFASLWKKY-ALKMRLRNLLGLSEELARKTAEEIIELELELSR---SAFDHRMNRDPRL 260
            .|.:.::...:...| ||..||.::||...  |...:.||::||.:|:.   |.::.:......:
Zfish   309 YLGQDEDSVKILASYKALMERLLSMLGAHN--ATLKSREILDLETKLANITVSEYEDQRKDISSM 371

  Fly   261 MRHLTM--LSNMSDAYGPILNVTRFVTSWLGSEYNLPVFESVPSYLFQVKKILLSTPNHVVANYM 323
            ...:|:  |..|:.::.....:.|........|..:.|..:  .|:..|..|:.:|...|:.|||
Zfish   372 YNRITLKQLQKMAPSFHWKRLLDRIFNDNFSEEEEIVVLAT--DYMQTVSDIIKTTSKRVLHNYM 434

  Fly   324 L--------SSLLTDFEITANE--------EQQKVICHERITELFPDVVDHMVYHSLEQQNPYIA 372
            |        ..|.|.|..|.:|        |||..:  ||:              .|.|.|.:..
Zfish   435 LWRMVAALSEHLSTAFRSTIHEFSREIDGTEQQLDL--ERL--------------CLTQANKHFG 483

  Fly   373 NEMRSLWVE--LKSSFREMLSS-------------PDIEWLEKQTREELLEKLNGMSFEIAGG-- 420
            ..:.:|:|:  ..||.|..:..             .:::|::::|::....||..|.  :..|
Zfish   484 MALGALFVQQHFSSSSRAKVQELVEDIKHSLDVRLQELDWMDEETKDAARGKLQHMM--VMTGYP 546

  Fly   421 ------QAVNFEEQFGDLVVSSADYYGNIQRLLEVKARILRTDLLRE-SSSVYYYHGVTATPIYE 478
                  :.::.|..|.   |:...|:.||...::...::....:.:| ..:.:..........|.
Zfish   547 DFLLKPELIDEEYAFD---VNEKTYFKNILNSIKYNIKLSIKKIHKEVDKTTWLLPPQALNAYYL 608

  Fly   479 TETNLVVLPVSYMQHRYLWDDIYPAALKYGTLGFTMAHEMAHGFDDLNRLYDSRGNLNDNWSTQT 543
            ...|.:|.|...:|.. |:|..:|.:|.||.:|..:.||:.||:||....||..|||...|:.::
Zfish   609 PNKNQMVFPAGILQPT-LYDPEFPQSLNYGGIGAIIGHELTHGYDDWGGQYDRYGNLKQWWTEES 672

  Fly   544 KVGFELVKNCLADQFSGMLYGNLRLRRLKSQAESIADNVGIRIAQSAYWKWLDQVEMEETESLPH 608
            ...|:....|:...:......|.|:....:..|:|||..|::::..||.||:.:...|  ..||.
Zfish   673 YRKFQKKTECIVKLYDNFTVYNQRVNGRLTLGENIADLGGLKLSYHAYQKWVREHGPE--RPLPG 735

  Fly   609 MTQSPEQLFFLSAAQFMCSDIYPERRANFV----RNNFHPPYEARVFAMMINSPAFAEAFQCSNS 669
            :..:.|||||::.||..|.    :||:..:    ..:.|.|...||...:.....|...|.|...
Zfish   736 LKHTHEQLFFIAFAQNWCM----KRRSQSIYLQLLTDKHAPEHYRVIGSVSQFEEFGRVFHCPRG 796

  Fly   670 SKMNPPNKCLMY 681
            |.|||.|||.::
Zfish   797 SPMNPVNKCSVW 808

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl17	NP_651641.1	M13	55..678	CDD:341056	165/703 (23%)
ecel1	NP_001429584.1	None