Protein Alignment WASp and wasa

DIOPT Version :9

• Sequence 1: NP_001263045.1
• Gene: WASp / 43402
• FlyBaseID: FBgn0024273
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: XP_699919.5
• Gene: wasa / 571256
• ZFINID: ZDB-GENE-081104-419
• Length: 630
• Species: Danio rerio
• Alignment Length: 702
• Identity: 197/702 - (28%)
• Similarity: 279/702 - (39%)
• Gaps: 251/702 - (35%)

  Fly     5 MRSQDGPRAKVNAASTLLTQEENEAVFKLLGKKCQTLNTAVVQIYKTEGSAHAHWKKRHTGVVCF 69
            ||.....:|:..:.|:||:.:|||.:..|||::|.:|::||||:.....|....|..:.:|||||
Zfish     1 MRRAAKGKAQECSGSSLLSIQENEKLEDLLGRRCVSLSSAVVQLLMALPSDPNRWTPQQSGVVCF 65

  Fly    70 VKDSAIRSYFMRAYCLIKNELIWEHEIYDGMEVVKSRPFLLTFEGSDGHVGLNFVSEEECDSFFR 134
            ||||::||:|:|.|.:...:|:||.|||:.:...|::||..||.|.|..|||||....|.::||.
Zfish    66 VKDSSLRSFFIRLYDIKAGKLVWEQEIYNQLMYQKTKPFFHTFPGDDCQVGLNFADVIEAENFFA 130

  Fly   135 IVDATIETRNRKRQEKRNRQKSQQAPNAPLPQVQREPARPPPMQGGLSSTDGVQLRNNKINSVTL 199
            :|:..|..||.:..||:.|:.|:......||.:      |||.          .:.:|..|.:..
Zfish   131 VVEDKIMQRNNRFAEKQQRKGSETRDRGALPPL------PPPN----------AVPSNVQNQIIP 179

  Fly   200 TPAPAPAQSKNFLSSSFGLGNNAKDKK-RKVTKADISRPTNFVHLSHVGWDAQKGFDLAGNENDE 263
            |.:....:.|.         ..:|:|| .|:.|.||..|:.|.|:||:|        :|||..|.
Zfish   180 TKSKKEKKEKE---------KKSKNKKGSKLLKGDIGAPSGFTHVSHLG--------MAGNSIDP 227

  Fly   264 VLNEFFVKAGVSEVELKDRDTRAFIYDFIQSNNVLASVK-----QYSVESPTET----------- 312
            .:.:....||:||..::|.:|...|||.|:.:..:.::|     |.|...|..:
Zfish   228 DVKKLLSCAGISEAAMEDSETSQLIYDVIERSGGMEALKKEMSQQESSRPPVPSGHRGSLPQVPS 292

  Fly   313 -AAPMP---------PPVPTRHPSNGNQR------------TAPP---LPPARQ----------- 341
             :||.|         ||||.:..:..:||            :|||   |.|||.
Zfish   293 GSAPPPLPQGRMGPLPPVPGQGSAPPSQRGSLPPTPPRAAGSAPPPGGLLPARSASLGPLPNVPP 357

  Fly   342 ------------------PPPAV------------------------------------------ 346
                              |||..
Zfish   358 GGRTGPLPQPPGPRSGPLPPPPTNRSGGLPPPLPGERRESLAPLPGKRPGAQGSERRGNSLPPQP 422

  Fly   347 ----PVTVPGAARAP-PPPNR------PPPIST-------------------------------- 368
                |...|||..:| |||.|      |||:.:
Zfish   423 AQTRPPLPPGARSSPLPPPQRDNSEFLPPPLESEMPPPPSDFFPPPPCDSFLPPPPDDFVNSMPP 487

  Fly   369 -----------------APPPPPVSA-PVVAPPPPPPPPPAAVPPPP--PPPMPVGEIPVITTTH 413
                             ||||||:|: |....||||||||||.||||  ||||..|..|
Zfish   488 PHPSQSNFPSRNISSGYAPPPPPISSKPSGGGPPPPPPPPAAPPPPPAAPPPMNFGSSP------ 546

  Fly   414 APTQAARPAAPAAPDPRNALMDAIRKGTQLKKVDTTALSTGSGDSRSDLMKDIRQGTVLKPAKER 478
             .:.||.||:......|.||:..|:.|.:||||      |.|.:..|             ||:
Zfish   547 -SSAAAPPASSGEEGGRGALLAQIQTGMKLKKV------TASQEPPS-------------PAQ-- 589

  Fly   479 ELGSQRNSDSGAGTDALADALRRALAARGNAIH-SDEDE--TESSDNEGEWD 527
                    |||.|   :..||...:..|...|| ||||:  .:..|::.|||
Zfish   590 --------DSGEG---IVGALMMVMQKRSKVIHSSDEDDEFDDEDDDDEEWD 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WASp	NP_001263045.1	WH1	31..140	CDD:144235	47/108 (44%)
		PBD	233..291	CDD:279166	20/57 (35%)
		WH2	<433..453	CDD:280384	7/19 (37%)
wasa	XP_699919.5	EVH1_WASP-like	36..136	CDD:269916	43/99 (43%)
		CRIB	205..254	CDD:294082	19/56 (34%)
		PHA03215	<389..439	CDD:223010	5/49 (10%)
		WH2	559..583	CDD:280384	11/29 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I6904
eggNOG	1	0.900	-	-		E1_KOG3671
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55182
OrthoDB	1	1.010	-	-		D1407277at2759
OrthoFinder	1	1.000	-	-		FOG0001481
OrthoInspector	1	1.000	-	-		otm25776
orthoMCL	1	0.900	-	-		OOG6_104030
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2175
SonicParanoid	1	1.000	-	-		X2034
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.720