Protein Alignment WASp and was

DIOPT Version :9

• Sequence 1: NP_001263045.1
• Gene: WASp / 43402
• FlyBaseID: FBgn0024273
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001107675.1
• Gene: was / 496673
• XenbaseID: XB-GENE-5759991
• Length: 476
• Species: Xenopus tropicalis
• Alignment Length: 567
• Identity: 194/567 - (34%)
• Similarity: 265/567 - (46%)
• Gaps: 139/567 - (24%)

  Fly     7 SQDGPRAKV----NAASTLLTQEENEAVFKLLGKKCQTLNTAVVQIYKTEGSAHAHWKKRHTGVV 67
            |:.||:|.|    |.:|:||..:||:.||:|||:||.||.|.|||:...:|.  ..|.|:..||:
 Frog     2 SRGGPKAAVRQQDNVSSSLLLPQENQKVFQLLGRKCTTLATTVVQLLVAQGG--DRWAKQFLGVL 64

  Fly    68 CFVKDSAIRSYFMRAYCLIKNELIWEHEIYDGMEVVKSRPFLLTFEGSDGHVGLNFVSEEECDSF 132
            |.|||:..|||:.:.:.|.:.:.:||.|:|:.:..:.:||:..||...:...||||..|.|...|
 Frog    65 CLVKDNPRRSYYFQLFDLQEEKAVWEQELYEQLRYLPARPYFHTFCSDECQTGLNFADEAEAADF 129

  Fly   133 FRIVDATIETRNRKRQEKRNRQKSQQAP---------NAPLPQVQREPARPPPMQGGLSSTDGVQ 188
                ...:|.:.:|:|.:::|:::...|         :.|||    .|..|.|...|.||
 Frog   130 ----QVVVEEKLKKKQHRQDRRQNLPPPPPVSDDRRTSLPLP----PPPGPGPFPNGPSS----- 181

  Fly   189 LRNNKINSVTLTPAP-APAQSKNF-----------------LSSSFGLGNNAKDKKRKVTKADIS 235
                        |.| ||:||.|.                 ||:....|.|.|.|| |.:||||.
 Frog   182 ------------PQPLAPSQSLNMPAVSIPNPDITSARYRALSAPADKGKNKKGKK-KFSKADIG 233

  Fly   236 RPTNFVHLSHVGWDAQKGFDLAGNENDEVLNEFFVKAGVSEVELKDRDTRAFIYDFIQSNNVLAS 300
            .|:.|.|:||||||...|||:  |:.|..:...|.:||:|:.:|||.:|...|||||:....:.:
 Frog   234 APSGFKHVSHVGWDPNSGFDV--NQLDPDIRNLFSRAGISDAQLKDAETSKLIYDFIEQQGGVEA 296

  Fly   301 VKQYSVESPTETAAPMPPPVPTRHPSNGNQRTAPPLP-PAR-----QPPPAVPVTVPGAARAPPP 359
            ||......  |||.|.|||          .|.|||.| |:|     .|||.|     ..:.||||
 Frog   297 VKNEMRRG--ETAPPPPPP----------SRNAPPAPTPSRGRTGPLPPPPV-----RGSSAPPP 344

  Fly   360 PNRPPPISTAPPPPPVSAPVVAPPPPPPPPPAAVPPPP-----PPPMPVGEIPVITTTHAPTQAA 419
               |||..:.||.||.:|....|||||||||:...|||     |||.|    ||..|...|
 Frog   345 ---PPPSRSTPPIPPPTARSGGPPPPPPPPPSIPAPPPTSGPAPPPPP----PVSGTQSIP---- 398

  Fly   420 RPAAPAAPDPRNALMDAIRKGTQLKKVDTTALSTGSGDSRSDLMKDIRQGTVLKPAKERELGSQR 484
               :|.....|.||:|.||:||:|.|:..:|                      :|....:..|
 Frog   399 ---SPTPSGGRGALLDQIRQGTKLNKLTVSA----------------------EPPPSPQPSS-- 436

  Fly   485 NSDSGAGTDALADALRRALAARGNAIHS---DEDETESSDNE-GEWD 527
                    :.|..||...:..|..||||   |:||..:.|:| .|||
 Frog   437 --------EGLVGALMHVMQKRSKAIHSSDDDDDEDGADDDEDDEWD 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WASp	NP_001263045.1	WH1	31..140	CDD:144235	40/108 (37%)
		PBD	233..291	CDD:279166	26/57 (46%)
		WH2	<433..453	CDD:280384	9/19 (47%)
was	NP_001107675.1	EVH1_WASP-like	39..137	CDD:269916	35/103 (34%)
		PBD	231..286	CDD:334253	25/56 (45%)
		WH2	405..421	CDD:128542	9/15 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9778
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001481
OrthoInspector	1	1.000	-	-		oto102574
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000