Protein Alignment WASp and viro-2

DIOPT Version :9

• Sequence 1: NP_001263045.1
• Gene: WASp / 43402
• FlyBaseID: FBgn0024273
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_741212.2
• Gene: viro-2 / 3565684
• WormBaseID: WBGene00015107
• Length: 616
• Species: Caenorhabditis elegans
• Alignment Length: 692
• Identity: 153/692 - (22%)
• Similarity: 229/692 - (33%)
• Gaps: 268/692 - (38%)

  Fly    19 STLLTQEENEAVFKLLGKKCQTLNTAVVQIYKTEGSAHAHWKKRHTG--VVCFVKDSAIRSYFMR 81
            |..|...|.|:|.:.:....:.|::.:.|....|   :|.|:|...|  |..|:|:|..|.|
 Worm     7 SDFLEINEKESVLRGISASDKILSSGICQFLVAE---NAQWRKPDEGAAVALFLKNSTERYY--- 65

  Fly    82 AYCLIKNELI---------WEHEI-YDGM------EVVKSRPFLLTFEGSDGHVGLNFVSEEECD 130
                   .:|         ||..: :|.:      |.::....||.||....::||||...:||:
 Worm    66 -------RIIVMEPSADPDWEPTVQFDFLIRDKKFETMQEHARLLVFEAESRYIGLNFYDSKECE 123

  Fly   131 SFFRIVDATIETRNRKRQEKRNRQKSQQAPNAPLPQVQREPARPPPMQGGLSSTDGVQLRNNKIN 195
            :|...|        .||| .|:..|::|                |.::|
 Worm   124 NFHNSV--------CKRQ-TRSTDKAKQ----------------PALEG---------------- 147

  Fly   196 SVTLTPAPAPAQSKNFLSSSFGLGNNAKDKKRKVTKADISRPTNFVHLSHVG-WDAQKG------ 253
                       :.|..:|....|..:..:.|.:|   :|..||:|.|:..|. .|.|:.
 Worm   148 -----------KKKKKISFFHNLFKSHSESKNQV---EIGAPTDFRHVDGVKLTDVQEDLYMQVR 198

  Fly   254 --FDLAGNENDEVLNEFFVK---------------AGVSEVELKDRD------------------ 283
              .::...|.:|::.:..|:               ..|.||:.|::|
 Worm   199 SKLNVNNPEEEEIVKQVIVRNEDHIRQSLMVKKESQTVKEVKDKNKDKKKSKSFFGRNKPKVEDV 263

  Fly   284 ---------------------TRAFIYDFIQSNNVLAS-------------VKQYSVESP----- 309
                                 |.:....|..|:.|.|:             :|....|:|
 Worm   264 SQPIVPVITGDPLNPDWTSNSTSSMSASFRSSSTVTAATSFKHSHTFAADPIKTTDWETPRKDTY 328

  Fly   310 --TETAAPM------------------------PPPVPTR----------------------HPS 326
              |....|.                        ||.:|:|                      |..
 Worm   329 GSTNQRQPQNIYKFEQEHVEQTYQIEKIEMDDTPPELPSRGASRNPEDQMTRGGLSTPRIPTHRD 393

  Fly   327 NGNQRTAPPLPPARQPPPA------------------VPVTVPGAARAPPPPNRPP----PISTA 369
            :....|.|...|.:.|||.                  |....|.....||||:.||    ||||.
 Worm   394 SYRWATKPDTVPKQTPPPTPNAPSHSHQVDQFAEFKLVEPKTPTRVAPPPPPSAPPTIKFPISTG 458

  Fly   370 P---PPPPVSAPVVAPPPP-------PPPPPAAV--PPPPPPPMPVGEIPVITTTHAPTQAARPA 422
            |   ...|.:.|..|||||       |.|.||.|  .||||||:|    |:.|.:..|     |.
 Worm   459 PSYSSTTPPTTPKPAPPPPSRIPNPSPSPQPAEVSKSPPPPPPLP----PIATPSSVP-----PP 514

  Fly   423 APAAPDPRNALMDAIRKGTQLKKVDTTALSTGSGDSRSDLMKDIR---QGTVLKPAKERELGSQR 484
            .|..|.|..||...|   :....|..||:...:.|.|| ||..||   :..||:...:.....|.
 Worm   515 PPPPPPPPPALEQEI---SGPPTVRLTAVPESNSDRRS-LMDQIRSTDRSQVLRKVSDTPETRQS 575

  Fly   485 NSDSGAGTDALADALRRALAARGNAIHSDEDETESSDNEGEW 526
            ...:.:||  :.|.::..|.||.:.|:..:.| ||.|::.||
 Worm   576 VPSTTSGT--IVDQIQNFLDARRSGINPSDSE-ESDDDDDEW 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WASp	NP_001263045.1	WH1	31..140	CDD:144235	30/126 (24%)
		PBD	233..291	CDD:279166	17/120 (14%)
		WH2	<433..453	CDD:280384	5/19 (26%)
viro-2	NP_741212.2	PH-like	23..133	CDD:388408	31/130 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	110	1.000	Inparanoid score	I3450
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050