Protein Alignment WASp and wsp1

DIOPT Version :9

• Sequence 1: NP_001263045.1
• Gene: WASp / 43402
• FlyBaseID: FBgn0024273
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_594758.1
• Gene: wsp1 / 2543589
• PomBaseID: SPAC4F10.15c
• Length: 574
• Species: Schizosaccharomyces pombe
• Alignment Length: 684
• Identity: 154/684 - (22%)
• Similarity: 230/684 - (33%)
• Gaps: 288/684 - (42%)

  Fly    19 STLLTQEENEAVFKLLGKKC-QTLNTAVVQIYKTEGSAHAHWKKRHTGVVCFVKDSAIRSYFMRA 82
            |:.:|||:...:.|.:.|.. :.:..|||::|......:   |..:|| :|   .:.:.||...|
pombe     4 SSSITQEDKATIRKYIPKSTNKIIAAAVVKLYVAYPDPN---KWNYTG-LC---GALVLSYDTTA 61

  Fly    83 YC-------LIKNE-LIWEHEIYDGMEVVKSRPFLLTFEGSDGHVGLNFVSEEECDSFF-RIVD- 137
            .|       ::.|. :||:.|:|..|:..:.|.|..:||......|.:|.:|.:...|: :::|
pombe    62 KCCWFKLVDVVNNSGIIWDQELYQNMDYRQDRTFFHSFELDKCLAGFSFANETDAQKFYKKVLDK 126

  Fly   138 ----ATIE-------TRNRKRQEKRNRQKSQQAPNAPLPQVQREPARPPPMQGGLSSTDGVQLRN 191
                .:||       ||         :..|:.|||....|   .|:..||:.|           .
pombe   127 GCHPESIENPVLSFITR---------KGSSRHAPNNSNIQ---PPSAAPPVPG-----------K 168

  Fly   192 NKINSVTLTPAPAPAQSKNFLSSSFGLGNNAKDKKRKVTKADISRPTNFVHLSHVGWDAQKGFDL 256
            ...|:|                     |:.:.::...:
pombe   169 ENYNAV---------------------GSKSPNEPELL--------------------------- 185

  Fly   257 AGNENDEVLNEFFVKAGVSEVELKDRDTRAFIYDFIQSNNVLASVKQYSVES---PTET------ 312
              |..|..|.:..:|.|:|:.::.:.      .||         ||.|..||   ||.|
pombe   186 --NSLDPSLIDSLMKMGISQDQIAEN------ADF---------VKAYLNESAGTPTSTSAPPIP 233

  Fly   313 ---------------AAPMPPPVPTRHPSNG----------------------NQRTAPPLPP-- 338
                           :||.|||:|.  ||||                      |..:.|||||
pombe   234 PSIPSSRPPERVPSLSAPAPPPIPP--PSNGTVSSPPNSPPRPIAPVSMNPAINSTSKPPLPPPS 296

  Fly   339 ------------ARQPPP-----------------------------------AVPVTVPGAARA 356
                        .|.|||                                   ::|:...|.:..
pombe   297 SRVSAAALAANKKRPPPPPPPSRRNRGKPPIGNGSSNSSLPPPPPPPRSNAAGSIPLPPQGRSAP 361

  Fly   357 PPPPNR--------PPPISTA------PPPPPV----SAPVVAP---------PPPPPPP----- 389
            ||||.|        |||:|::      |.|||.    |||.:.|         ||.|.||
pombe   362 PPPPPRSAPSTGRQPPPLSSSRAVSNPPAPPPAIPGRSAPALPPLGNASRTSTPPVPTPPSLPPS 426

  Fly   390 -PAAVPPPPPPPMPVG---------EIPVITTTHAPTQAARPAAPAAPDPRNALMDA----IRKG 440
             |.::||..||.:|:|         ..|:.....|...||.|..||||.|..|...|    :...
pombe   427 APPSLPPSAPPSLPMGAPAAPPLPPSAPIAPPLPAGMPAAPPLPPAAPAPPPAPAPAPAAPVASI 491

  Fly   441 TQLKKVDTTALSTGSGDSRSDLMKDIRQGTVLKPAKERELGSQRNSDSGAGT------------D 493
            .:|.:          .|.|::||..||....:...|.|::.:   |.|.|.|            :
pombe   492 AELPQ----------QDGRANLMASIRASGGMDLLKSRKVSA---SPSVASTKTSNPPVEAPPSN 543

  Fly   494 ALADALRRALAARGNAIHSDEDETESSDNEGEWD 527
            .|.|||..||..|...:...::|.|..|   |||
pombe   544 NLMDALASALNQRKTKVAQSDEEDEDDD---EWD 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WASp	NP_001263045.1	WH1	31..140	CDD:144235	29/123 (24%)
		PBD	233..291	CDD:279166	6/57 (11%)
		WH2	<433..453	CDD:280384	2/23 (9%)
wsp1	NP_594758.1	EVH1_WASP-like	26..126	CDD:269916	26/106 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3671
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001481
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2175
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.890