Protein Alignment WASp and wsp-1

DIOPT Version :9

• Sequence 1: NP_001263045.1
• Gene: WASp / 43402
• FlyBaseID: FBgn0024273
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001379549.1
• Gene: wsp-1 / 177616
• WormBaseID: WBGene00006957
• Length: 781
• Species: Caenorhabditis elegans
• Alignment Length: 524
• Identity: 164/524 - (31%)
• Similarity: 216/524 - (41%)
• Gaps: 143/524 - (27%)

  Fly   115 SDGHVGLNFVSEEE---C----DSFFRIVDAT---IETRN----------RKRQEKRNRQKSQQA 159
            |:|.|.:....:||   |    ||......||   :|...          |.|..|::...:..:
 Worm   287 SNGQVSVMVTKKEEPIYCSGGSDSSTESSSATPSSVEADTPPPIPSHPPARHRLVKKSSSSTSIS 351

  Fly   160 PN----APLPQVQREPA-----RPPPMQ--GGLSSTDGVQLRNNKINSVTLTPAPAPAQSKNFLS 213
            .|    .|..|.:...|     |.|||.  ||...|          ...|:..||......:..:
 Worm   352 LNGIGSTPTRQFEITQAYGGTIRGPPMAIGGGQGIT----------QMGTMAAAPQSHTHTDGNA 406

  Fly   214 SSFGL-----GNNAKDKKRKVTKADISRPTNFVHLSHVGWDAQKGFD--LAGNENDEVLNEFFVK 271
            ||.|.     .|..||||.|:.|.|||.||||.|.:||||:...||.  :..::.||........
 Worm   407 SSSGSWFRKDKNKKKDKKSKIKKEDISNPTNFQHKAHVGWNQDSGFSNTVYDDDMDEATKNILKA 471

  Fly   272 AGVSEVELKDRDTRAFIYDFIQSNNVLASVKQYSVES--PTETAAPMPPPVPTRHP--------- 325
            ||:....|.: |.:.|:..||..|    ..|..||.|  |::.::|:|||: .:||
 Worm   472 AGLESNNLNE-DDKKFVKKFIAKN----YDKYVSVGSLDPSQISSPLPPPI-QQHPQMNQSWNQT 530

  Fly   326 -------------------SNGNQRTAPPLP---------PARQPPPAVPVTVPGAARAPP---- 358
                               |:.:...|||.|         |||.|||.......|.|.:.|
 Worm   531 PVRQYKPSFPSSAPIGSGASSYSTPAAPPPPTRVESHGLAPARPPPPPPSSGTRGIAPSRPLPQA 595

  Fly   359 -----PPNRPPPISTAPPPPPVS----APV--VAPPPPPPPPP-------AAVPPPPPPPMPVGE 405
                 |.|||..:...|||||..    ||:  .||||||||||       |..|||||||.|.|
 Worm   596 PNYGTPENRPHAVPPPPPPPPPQSFGMAPISSAAPPPPPPPPPMGLPAVGAGAPPPPPPPPPSG- 659

  Fly   406 IPVITTTHAPTQAARPAA-----PAAPDPRNALMDAIRKGTQLKKVDTTALS--TGSGDSRSDLM 463
                        |..||:     |.|.|.|:.|:..|:.|.||:.|..||.|  :..||:|.|:|
 Worm   660 ------------AGGPASVLAKLPPAQDGRSNLLAEIQAGKQLRSVQQTADSPKSAGGDARGDVM 712

  Fly   464 KDIRQGTVLK---PAKERELGSQRNSDSG-AGTDALADALRRALAAR--GNAIHSDEDETESSDN 522
            ..||||..||   .|.|:|  .::::.|| ||...||.||.:||..|  ...|....|:.:..|:
 Worm   713 AQIRQGAQLKHVDAAAEQE--RRKSTTSGAAGMGGLAGALAKALEERRMNMGIDDTSDDDDDEDD 775

  Fly   523 EGEW 526
            :.||
 Worm   776 KNEW 779

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WASp	NP_001263045.1	WH1	31..140	CDD:144235	10/34 (29%)
		PBD	233..291	CDD:279166	21/59 (36%)
		WH2	<433..453	CDD:280384	9/21 (43%)
wsp-1	NP_001379549.1	PBD	432..494	CDD:395634	22/62 (35%)
		WH2_Pan1-like	673..694	CDD:409213	8/20 (40%)
		WH2_WAVE-2	705..733	CDD:409215	14/29 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I8353
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D594307at33208
OrthoFinder	1	1.000	-	-		FOG0001481
OrthoInspector	1	1.000	-	-		oto20242
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2175
SonicParanoid	1	1.000	-	-		X2034
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.040