DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment WASp and wasll

DIOPT Version :9

Sequence 1:	NP_001263045.1	Gene:	WASp / 43402	FlyBaseID:	FBgn0024273	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	XP_002934285.2	Gene:	wasll / 100489197	XenbaseID:	XB-GENE-22061520	Length:	404	Species:	Xenopus tropicalis

Alignment Length:	400	Identity:	98/400 - (24%)
Similarity:	149/400 - (37%)	Gaps:	131/400 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   226 KRKVTKADISRPTNFVHLSHVGWDAQKGFDLAGNENDEVLNEFFVKAGVSEVELKDRDTRAFIYD 290
            :||::|:||..|:||.||:||||.:....|   ...|..|.:.|..||:.|..|||::....|:.
Frog    37 RRKLSKSDIGSPSNFKHLAHVGWPSGTNLD---ERTDADLKKLFKLAGIKEEHLKDQEMSRKIFA 98

  Fly   291 FIQSNNVLASVK--------------QYSVESPTETAAPMPP-----PVPTRHPSNGNQRTAPPL 336
            .|:....:.:|:              :|...|.:.|....|.     ||.:.|.:.....|.|..
Frog    99 VIEKKGGMEAVRKETLRMAQREMPDSRYKYRSRSSTNQTPPKRQNSFPVTSHHAAKIPVTTLPSS 163

  Fly   337 P----------PARQP--------------PPAV-----PVTVPG-------------------A 353
            |          |:.||              ||.:     ||..|.                   :
Frog   164 PFSYIASLHRMPSAQPSPLGDFPSLSPIPSPPLLLGDFSPVPTPAQNKISPQTSIEIKTSLTDVS 228

  Fly   354 ARAPPPPNRPPPISTAPPPPPVSAPVVAPP------------PPPPPPP----------AAVPPP 396
            ||...|| |||.:.:|...|.:..|:.:.|            |..|..|          |:||||
Frog   229 ARPAIPP-RPPTLLSAKDSPLIPLPLPSLPASVHKSSSELSFPCQPQSPASCQHNDIQHASVPPP 292

  Fly   397 PPPPMPVGEIPVITTTHAPTQA--ARPAAPAAP---DPRNALMDA---IRKGTQLKKVDTTALST 453
            |||      ||......:|.:|  ..|:.|...   .|...:|..   |.:|.:  |:...:|
Frog   293 PPP------IPPFLKKESPEKACLVLPSCPVEELHNSPLKCMMQTEKEIHRGKE--KLRDPSL-- 347

  Fly   454 GSGDSRSDLMKDIRQGTVLKP-AKERELGSQRNSDSGAGTDALADALRRALAARGNAIHSDEDET 517
                    .::.||||..||. ::..::.|.:||       .:..||...:..|..|:|..:|||
Frog   348 --------FLEQIRQGVQLKSISRPSKIESSQNS-------TIVSALMDVIQKRHKALHGSDDET 397

  Fly   518 ESSDNEGEWD 527
            :    :.||:
Frog   398 D----DDEWE 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
WASp	NP_001263045.1	WH1	31..140	CDD:144235
		PBD	233..291	CDD:279166	22/57 (39%)
		WH2	<433..453	CDD:280384	5/22 (23%)
wasll	XP_002934285.2	PBD	44..89	CDD:334253	19/47 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1407277at2759
OrthoFinder	1	1.000	-	-		FOG0001481
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010