DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1647 and zbtb48

DIOPT Version :9

Sequence 1:NP_651636.1 Gene:CG1647 / 43401 FlyBaseID:FBgn0039602 Length:1222 Species:Drosophila melanogaster
Sequence 2:XP_696166.2 Gene:zbtb48 / 567773 ZFINID:ZDB-GENE-030131-4450 Length:760 Species:Danio rerio


Alignment Length:555 Identity:110/555 - (19%)
Similarity:187/555 - (33%) Gaps:173/555 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 DNPGKVPILLP-NEEDTIDLDEP----------RMSQKIYELVGFTVSVDDKMPQTICSQC---- 75
            |..|.|.|::. .:|:.:..|.|          |..:...:..|...|.|.|.....|..|    
Zfish   267 DRGGSVDIIIEGTDEEYVPHDSPCSSTKTPRGKRKEKSSNKKNGEGTSKDSKKGAVQCPTCHKTF 331

  Fly    76 VDKINDFYEFREMCYATNKQTRNLLGLKQIEPARLIDLKRIVKEERPISGAVGKRG----RKRKG 136
            :.|           |......|...|                  |:|..  .||.|    ||...
Zfish   332 LSK-----------YYLKVHNRRHTG------------------EKPFK--CGKCGKCYFRKENL 365

  Fly   137 EESWPKNNNVKPQV----KKESFVWHKKQKLQ----------PSQITS----LVSKREPEIKDEP 183
            .|...:|...:.::    .|.|..:.|:|:|:          |::.||    .:.||:.:|    
Zfish   366 LEHEARNCLTRTELVFSCSKCSMTFKKRQELRHHTVMHTGVMPNKCTSCPEQFMQKRDLKI---- 426

  Fly   184 AEQDTSLKGPPKKAGRKSICSVCGEKFLSK-EL----ADEHKS-------------------LVH 224
              ....:.|.||    ...|.:|.:.|||: ||    |.:|:.                   .:|
Zfish   427 --HMIKVHGAPK----PHACPLCPKCFLSRTELRLHEASKHRGEKLFVCEECGHRASSRNGLQMH 485

  Fly   225 VPSIPR----YICNACNQTHHNQSDIRAHQLWHKLSKTPYKCPLCESSVANAYAFTRHLREHTPP 285
            :.:|.|    ::|..||.....::::..|...|...| |::|.||..:.....:..:|.|.||..
Zfish   486 IKAIHRNERPFVCQLCNHAFTQKANLSMHLRTHTGEK-PFQCHLCGKTFRTQASLDKHHRTHTGE 549

  Fly   286 TPVQLLVLDRE----------------------CPLCKKTFVT----NFFYNTHRCAIRKRKCGG 324
            .|......::.                      |.:|.|||..    ......|: .:||.:|..
Zfish   550 RPFSCEFCEQRFTEKGPLLRHIASKHQEGRPHFCQICNKTFKAIEQLRVHVRRHK-GMRKFECTL 613

  Fly   325 CSRTLNTEAAYMRHAPTCPKIYLNHSKHIMPQVVTNEAQMLIKNEIEEEL------LGLPPATTV 383
            |......:|...||.    :|: |..::..|:      |..::|.:.|:.      .|||..|..
Zfish   614 CGYKFTRQAHLRRHT----QIH-NRMENYSPR------QRRLRNLVVEDASAAAASSGLPVQTEA 667

  Fly   384 ---PPDFVIDEGMQPVVVL---------ERLSSPLLRSSSGTDQLVAAKSKNSDRVSARNYLKRV 436
               |.|.|      .:|:.         |:.|.|:...:...:|...|.::..|.|:...:  .|
Zfish   668 QAEPADIV------SIVIQQEGAAETGGEQASYPVTDGAVNAEQTGFALAEREDGVAQTEF--TV 724

  Fly   437 DQLLKNTINTLVSIKHEPEVHINDTGPPRGQAESD 471
            ..:::.|:  ||.::....:|.:|........|:|
Zfish   725 ADVMEQTL--LVRVQEAYPIHQSDVVVEIPNTEAD 757

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1647NP_651636.1 zf-AD 19..99 CDD:285071 17/87 (20%)
C2H2 Zn finger 203..224 CDD:275368 9/44 (20%)
C2H2 Zn finger 233..253 CDD:275368 4/19 (21%)
C2H2 Zn finger 262..282 CDD:275368 5/19 (26%)
C2H2 Zn finger 297..314 CDD:275368 5/20 (25%)
zbtb48XP_696166.2 BTB 18..109 CDD:279045
BTB 35..116 CDD:197585
C2H2 Zn finger 324..344 CDD:275368 5/30 (17%)
zf-H2C2_2 336..359 CDD:290200 7/42 (17%)
C2H2 Zn finger 352..403 CDD:275368 12/50 (24%)
C2H2 Zn finger 383..402 CDD:275368 5/18 (28%)
C2H2 Zn finger 411..432 CDD:275368 5/26 (19%)
C2H2 Zn finger 440..461 CDD:275368 8/20 (40%)
C2H2 Zn finger 469..490 CDD:275368 1/20 (5%)
COG5048 <495..643 CDD:227381 32/160 (20%)
C2H2 Zn finger 498..518 CDD:275368 4/19 (21%)
zf-H2C2_2 510..535 CDD:290200 7/25 (28%)
C2H2 Zn finger 526..546 CDD:275368 5/19 (26%)
zf-H2C2_2 538..562 CDD:290200 5/23 (22%)
C2H2 Zn finger 554..571 CDD:275368 0/16 (0%)
C2H2 Zn finger 586..603 CDD:275368 4/16 (25%)
zf-H2C2_2 596..620 CDD:290200 5/24 (21%)
C2H2 Zn finger 611..631 CDD:275368 5/23 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24406
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.100

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