DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1647 and IBSP

DIOPT Version :9

Sequence 1:	NP_651636.1	Gene:	CG1647 / 43401	FlyBaseID:	FBgn0039602	Length:	1222	Species:	Drosophila melanogaster
Sequence 2:	NP_004958.2	Gene:	IBSP / 3381	HGNCID:	5341	Length:	317	Species:	Homo sapiens

Alignment Length:	381	Identity:	75/381 - (19%)
Similarity:	118/381 - (30%)	Gaps:	156/381 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   450 IKHEPEVHINDTGPPRGQAESDPEPERNEEHPSFGDDIQAANDECQECQPETESDKISVAAC--- 511
            :|..|....:|:....|. :|..|.|..||..:.|::.:.:|::     .::|::..:::|.
Human    55 LKRFPVQGSSDSSEENGD-DSSEEEEEEEETSNEGENNEESNED-----EDSEAENTTLSATTLG 113

  Fly   512 ---DDIPSVSVKQEPEYDGYEKQTGVKQEPLKLKLKITKNHGKLNSSLIDDLDEAGQAFGRSSKK 573
               |..|..         ||   ||:....|..|                    ||....:::|:
Human   114 YGEDATPGT---------GY---TGLAAIQLPKK--------------------AGDITNKATKE 146

  Fly   574 KKKRKHKEREKEASNETENCRTESQNQPAIKIKQEPVDYAPEATVMTTIPMTQFESSLNESERSE 638
            |:..:.:|.|:|.                                             ||:|.||
Human   147 KESDEEEEEEEEG---------------------------------------------NENEESE 166

  Fly   639 -EVDEAMIQSQEDVKPNRMELDRMMQISNVTSGVDMAEEAMALERAEEACPEDSLHKVKSVKSTA 702
             ||||.. |.......|..|.:.    .|.:||.|..||... |....|..||:....:..|.|:
Human   167 AEVDENE-QGINGTSTNSTEAEN----GNGSSGGDNGEEGEE-ESVTGANAEDTTETGRQGKGTS 225

  Fly   703 RKST---GGAERKTYSPPRTNTLPQIVAVVSGESAFNMISIKPEPRNLGYGDEEPEDQRETTEEI 764
            :.:|   ||.|..|  ||:.                             |....|...:.||.|
Human   226 KTTTSPNGGFEPTT--PPQV-----------------------------YRTTSPPFGKTTTVE- 258

  Fly   765 NHNDMMEEEKEYIGSLDLSDVSVKQERELDICEIDAVHRNGLEKSDEDDDDGNEDS 820
                 .|.|.||.|:           .|.|         ||.|..:.::.:...|:
Human   259 -----YEGEYEYTGA-----------NEYD---------NGYEIYESENGEPRGDN 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1647	NP_651636.1	zf-AD	19..99	CDD:285071
		C2H2 Zn finger	203..224	CDD:275368
		C2H2 Zn finger	233..253	CDD:275368
		C2H2 Zn finger	262..282	CDD:275368
		C2H2 Zn finger	297..314	CDD:275368
IBSP	NP_004958.2	BSP_II	17..314	CDD:283165	75/381 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	58..254		60/315 (19%)
		cell-attachment tripeptide	286..288		0/1 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900