DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1647 and Zfx

DIOPT Version :9

Sequence 1:	NP_651636.1	Gene:	CG1647 / 43401	FlyBaseID:	FBgn0039602	Length:	1222	Species:	Drosophila melanogaster
Sequence 2:	XP_006528028.1	Gene:	Zfx / 22764	MGIID:	99211	Length:	832	Species:	Mus musculus

Alignment Length:	289	Identity:	63/289 - (21%)
Similarity:	98/289 - (33%)	Gaps:	57/289 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 FREMCYATNKQTRNLLGLKQIEPARLIDLKRIVKEERPISGAVGKRGRKRKGEESWPKNNNVKPQ 149
            |..:|....|..|:        |:.|....||...|:|..   .:....|..:.|     |:|..
Mouse   573 FPHICVECGKGFRH--------PSELKKHMRIHTGEKPYE---CQYCEYRSADSS-----NLKTH 621

  Fly   150 VKKESFVWHKKQKLQPSQITSLVSKREPEIKDEPAEQDTSLKGPPKKAGRKSICSVCGEKFLSKE 214
            ||.:    |.|:......|..|......|::........|         :...|..|..|..:..
Mouse   622 VKTK----HSKEMPFKCDICLLTFSDTKEVQQHALVHQES---------KTHQCLHCDHKSSNSS 673

  Fly   215 LADEHKSLVHVPSIPRYICNACNQTHHNQSDIRAHQLWHKLSKTPYKCPLCESSVANAYAFTRH- 278
            ....|...||....| :.|:.|::..|..|:::.|...|| .|..::|..|:..:|:.:..:||
Mouse   674 DLKRHIISVHTKDYP-HKCDMCDKGFHRPSELKKHVAAHK-GKKMHQCRHCDFKIADPFVLSRHI 736

  Fly   279 LREHTPPTPVQLLVLDRECPLCKKTFVTNFFYNTHRCAIRKRK---CGGCSRTLNTEAAYMRHAP 340
            |..||...|.:       |..|:|.|........|......||   |..|..:....:.:.||..
Mouse   737 LSVHTKDLPFR-------CKRCRKGFRQQSELKKHMKTHSGRKVYQCEYCEYSTTDASGFKRHVI 794

  Fly   341 T------------CPKIYLNHS---KHIM 354
            :            |.|.:...|   :|||
Mouse   795 SIHTKDYPHRCEYCKKGFRRPSEKNQHIM 823

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1647	NP_651636.1	zf-AD	19..99	CDD:285071	4/13 (31%)
		C2H2 Zn finger	203..224	CDD:275368	4/20 (20%)
		C2H2 Zn finger	233..253	CDD:275368	5/19 (26%)
		C2H2 Zn finger	262..282	CDD:275368	6/20 (30%)
		C2H2 Zn finger	297..314	CDD:275368	4/16 (25%)
Zfx	XP_006528028.1	Zfx_Zfy_act	104..437	CDD:368066
		zf-C2H2	452..474	CDD:333835
		C2H2 Zn finger	454..474	CDD:275368
		C2H2 Zn finger	485..509	CDD:275368
		C2H2 Zn finger	517..537	CDD:275368
		COG5048	570..>832	CDD:227381	63/289 (22%)
		C2H2 Zn finger	577..597	CDD:275368	6/27 (22%)
		C2H2 Zn finger	605..624	CDD:275368	5/23 (22%)
		C2H2 Zn finger	662..683	CDD:275368	4/20 (20%)
		C2H2 Zn finger	691..711	CDD:275368	5/19 (26%)
		C2H2 Zn finger	748..768	CDD:275368	5/19 (26%)
		C2H2 Zn finger	776..797	CDD:275368	4/20 (20%)
		C2H2 Zn finger	805..825	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100