DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1647 and si:dkeyp-2e4.2

DIOPT Version :9

Sequence 1:	NP_651636.1	Gene:	CG1647 / 43401	FlyBaseID:	FBgn0039602	Length:	1222	Species:	Drosophila melanogaster
Sequence 2:	NP_001122042.1	Gene:	si:dkeyp-2e4.2 / 100149164	ZFINID:	ZDB-GENE-030131-9307	Length:	251	Species:	Danio rerio

Alignment Length:	267	Identity:	62/267 - (23%)
Similarity:	95/267 - (35%)	Gaps:	54/267 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 LKRIVKEERPISGAVGKRGRKRKGEESWPKNNNVKPQVKKES------FVWHKKQKLQPSQITSL 171
            :|.::|.|..:.|          ..||...||:|:..|..::      |....|.:::..| ||.
Zfish     1 MKPVIKNEESLQG----------DPESKSTNNDVETLVLSKTEGSAALFCRRLKYRVKTDQ-TSD 54

  Fly   172 VSKREPEIKDE-PAEQDTSLKGPPKKAGRKSICSVCGEKFLSKELADEHKSLVHVPSIPRYICNA 235
            .|..:.:.:|| |.....:       .|...||.:||.:|.|......|.. :|....| |||..
Zfish    55 QSSSDTDTEDELPISTSPT-------PGEDLICKLCGSEFGSNISMVRHMR-IHTGETP-YICEV 110

  Fly   236 CNQTHHNQSDIRAHQLWHKLSKTP----YKCPLCESSVANAYAFTRHLREHTPPTPVQLLVLDRE 296
            |.:....|..::.|...|..:|..    ..|..||....::.|...||.:|....|.       .
Zfish   111 CGKGFKRQGWLKEHFRVHTGNKRKREKRLSCDQCEMKFNSSTALRSHLNKHRGERPF-------A 168

  Fly   297 CPLCKKTFVTNFFYNTH--RC-AIRKRKCGGCSRTLNTEAAYMRH-----------APTCPKIYL 347
            |..|.||:......|.|  .| :.:|..|..|......:::..:|           .|.|.|.:
Zfish   169 CVQCDKTYFNQHDLNQHLRDCHSDKKHGCYLCGNEFTRQSSLQKHMRIHTGERPYSCPHCGKTF- 232

  Fly   348 NHSKHIM 354
             ..||.|
Zfish   233 -SYKHSM 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1647	NP_651636.1	zf-AD	19..99	CDD:285071
		C2H2 Zn finger	203..224	CDD:275368	6/20 (30%)
		C2H2 Zn finger	233..253	CDD:275368	4/19 (21%)
		C2H2 Zn finger	262..282	CDD:275368	6/19 (32%)
		C2H2 Zn finger	297..314	CDD:275368	6/18 (33%)
si:dkeyp-2e4.2	NP_001122042.1	C2H2 Zn finger	80..100	CDD:275368	6/20 (30%)
		zf-H2C2_2	92..117	CDD:290200	7/26 (27%)
		C2H2 Zn finger	108..128	CDD:275368	4/19 (21%)
		C2H2 Zn finger	141..161	CDD:275368	6/19 (32%)
		C2H2 Zn finger	169..217	CDD:275368	11/47 (23%)
		zf-H2C2_2	209..234	CDD:290200	4/26 (15%)
		C2H2 Zn finger	225..243	CDD:275368	6/16 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100