DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1523 and AT1G24130

DIOPT Version :9

Sequence 1:	NP_651635.2	Gene:	CG1523 / 43400	FlyBaseID:	FBgn0039601	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_173823.1	Gene:	AT1G24130 / 839025	AraportID:	AT1G24130	Length:	415	Species:	Arabidopsis thaliana

Alignment Length:	257	Identity:	63/257 - (24%)
Similarity:	105/257 - (40%)	Gaps:	41/257 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 NSLMRRIYSSMNMFNSY-----HANCWPTDAGRTGAIFNLEFNADGNVVVAATERKCVLVFDAIT 79
            |...:.::||    .||     |..|  |......|:.:|..:.||:::.:|:..:...::....
plant   165 NDRFKTLFSS----KSYVEVRRHKKC--TWVHHVDAVSSLALSQDGSLLYSASWDRSFKIWRTSD 223

  Fly    80 QKEIFKVPDAHTDSVNCIKFFDERLFATGSDDFTVALWDLRNMKQKL-RVLHGHSNWVKNIEYSS 143
            .|.:..:..||.|::|.|....:....|||.|..:.:|:.::.|..| ..|..|.:.|..:..|.
plant   224 FKCLDSIEKAHDDAINAIVVSKDGFVYTGSADKKIKVWNKKDKKHSLVATLTKHLSAVNALAISE 288

  Fly   144 KDKLLVSSGFDGSIFTWD--INSQTEQGLISQRVFHAS--GLMRCRISPTGDKLVLCTSGGYIMI 204
            ..|:|.|...|.||..|:  ||...|:       .|.|  |.:|..     .|.::|     :.:
plant   289 DGKVLYSGACDRSILVWERLINGDDEE-------LHMSVVGALRGH-----RKAIMC-----LAV 336

  Fly   205 IHHLDLT-TLHKDLCGFRPGIYRLMQLGEQYIPQAAKYDHVFSKRQKKNRVELVTDFPENND 265
            ...|.|: :..|.|..:|.|   ||: .|.|...|....|.   :..|:....|:|...|:|
plant   337 ASDLVLSGSADKSLRVWRRG---LME-KEGYSCLAVLEGHT---KPVKSLAVSVSDSDSNSD 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1523	NP_651635.2	WD40	43..235	CDD:295369	48/197 (24%)
		WD40	<45..>218	CDD:225201	41/178 (23%)
		WD40 repeat	51..87	CDD:293791	5/35 (14%)
		WD40 repeat	95..129	CDD:293791	9/34 (26%)
		WD40 repeat	136..174	CDD:293791	12/39 (31%)
		WD40 repeat	181..210	CDD:293791	4/28 (14%)
AT1G24130	NP_173823.1	WD40	<61..415	CDD:225201	63/257 (25%)
		WD40	61..409	CDD:238121	63/257 (25%)
		WD40 repeat	73..115	CDD:293791
		WD40 repeat	120..162	CDD:293791
		WD40 repeat	196..231	CDD:293791	5/34 (15%)
		WD40 repeat	238..273	CDD:293791	9/34 (26%)
		WD40 repeat	281..325	CDD:293791	15/50 (30%)
		WD40 repeat	331..353	CDD:293791	5/26 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4155
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810