DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1523 and AT1G10580

DIOPT Version :9

Sequence 1:	NP_651635.2	Gene:	CG1523 / 43400	FlyBaseID:	FBgn0039601	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_172528.2	Gene:	AT1G10580 / 837599	AraportID:	AT1G10580	Length:	573	Species:	Arabidopsis thaliana

Alignment Length:	324	Identity:	66/324 - (20%)
Similarity:	113/324 - (34%)	Gaps:	91/324 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 YSSMNMFN-----SYHANCW---PTDAGRTGAIFNLEFNADGNVVVAATERKCVLVFDAITQKEI 83
            |:..:.|:     .|....|   |.||                   .|....|.:      .|.:
plant   235 YADKSTFHGKEEKDYQGRSWIEAPKDA-------------------KANNDHCYI------PKRL 274

  Fly    84 FKVPDAHTDSVNCIKFFDER--LFATGSDDFTVALWDLRNMKQKLRVLHGHSNWVKNIEYSSKDK 146
            ......||..|:.|:||.::  |..:...|..|.:||:.|..:.:|...||:..|::|.:|:...
plant   275 VHTWSGHTKGVSAIRFFPKQGHLLLSAGMDCKVKIWDVYNSGKCMRTYMGHAKAVRDICFSNDGS 339

  Fly   147 LLVSSGFDGSIFTWDINSQTEQGLISQRVFHASGLMRCRISPTGDKLVLCTSGGYIMIIHHLDLT 211
            ..:::|:|.:|..||    ||.|.:.............:::|..||..:..:|.....|...|:.
plant   340 KFLTAGYDKNIKYWD----TETGQVISTFSTGKIPYVVKLNPDDDKQNILLAGMSDKKIVQWDIN 400

  Fly   212 TLHKDLCGFRPGIYRLMQLGEQYIPQAAKYDHVFSKRQKKNRVELVTDFPENN-------DAEMI 269
            |                  ||  :.|  :||      |....|..:| |.:||       |.:.:
plant   401 T------------------GE--VTQ--EYD------QHLGAVNTIT-FVDNNRRFVTSSDDKSL 436

  Fly   270 MALQI----------HPHCCCMLTRNVSCDEQSEWTCIHDI-NEEPVRSEDEQDEVEPQPKRKR 322
            ...:.          .||...|  .::|......|.....: |:..:.|..|:.::.   |:||
plant   437 RVWEFGIPVVIKYISEPHMHSM--PSISVHPNGNWLAAQSLDNQILIYSTRERFQLN---KKKR 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1523	NP_651635.2	WD40	43..235	CDD:295369	40/193 (21%)
		WD40	<45..>218	CDD:225201	37/174 (21%)
		WD40 repeat	51..87	CDD:293791	3/35 (9%)
		WD40 repeat	95..129	CDD:293791	10/35 (29%)
		WD40 repeat	136..174	CDD:293791	11/37 (30%)
		WD40 repeat	181..210	CDD:293791	5/28 (18%)
AT1G10580	NP_172528.2	WD40	<271..573	CDD:225201	57/263 (22%)
		WD40	274..573	CDD:238121	56/260 (22%)
		WD40 repeat	285..324	CDD:293791	11/38 (29%)
		WD40 repeat	330..367	CDD:293791	10/40 (25%)
		WD40 repeat	372..409	CDD:293791	10/58 (17%)
		WD40 repeat	416..451	CDD:293791	5/35 (14%)
		WD40 repeat	458..497	CDD:293791	9/43 (21%)
		WD40 repeat	505..541	CDD:293791
		WD40 repeat	547..572	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910