DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1523 and AT5G08390

DIOPT Version :9

Sequence 1:	NP_651635.2	Gene:	CG1523 / 43400	FlyBaseID:	FBgn0039601	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_568194.2	Gene:	AT5G08390 / 830737	AraportID:	AT5G08390	Length:	839	Species:	Arabidopsis thaliana

Alignment Length:	635	Identity:	125/635 - (19%)
Similarity:	206/635 - (32%)	Gaps:	231/635 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 KEIFKVPD--AHTDSVNCIKF--FDERLFATGSDDFTVALWDLRNMKQKLRVLHGHSNWVKNIEY 141
            |..:|:.:  ||:.:|||:|.  ...|:..||.:|..|.||.: .....:..|:|||:.:.::.:
plant     4 KRAYKLQEFVAHSAAVNCLKIGRKSSRVLVTGGEDHKVNLWAI-GKPNAILSLYGHSSGIDSVTF 67

  Fly   142 SSKDKLLVSSGFDGSIFTWDINSQ---------------------------------------TE 167
            .:.:.|:.:....|:|..||:...                                       .:
plant    68 DASEGLVAAGAASGTIKLWDLEEAKVVRTLTGHRSNCVSVNFHPFGEFFASGSLDTNLKIWDIRK 132

  Fly   168 QGLISQRVFHASGLMRCRISPTGDKLVLCTSGGYIMIIHHLDLTTLHKDLCGFRPGIYRLMQLGE 232
            :|.|.....|..|:...|.:|.|..:|   |||...::...|||
plant   133 KGCIHTYKGHTRGVNVLRFTPDGRWIV---SGGEDNVVKVWDLT--------------------- 173

  Fly   233 QYIPQAAKYDHVFSKRQKKNRVELVTDFPENNDAEMIMALQIHPHCCCMLT-------------- 283
                 |.|..|.|...:.|                 |.:|..|||...:.|
plant   174 -----AGKLLHEFKSHEGK-----------------IQSLDFHPHEFLLATGSADKTVKFWDLET 216

  Fly   284 -----------------------RNVSCDEQS-----EWTCIHDINEEPVRSEDEQDEVEPQPKR 320
                                   ::|.|..|.     .|        ||:|..|..|
plant   217 FELIGSGGTETTGVRCLTFNPDGKSVLCGLQESLKIFSW--------EPIRCHDGVD-------- 265

  Fly   321 KRVSTTLASRSSLNE------SQDQDTVGLTPRQARR--PLRVSSVQVFQLDN------SGAGR- 370
              |..:..|..:::|      |.:|:.||:......|  |:...:.|    .|      ||:||
plant   266 --VGWSNLSDMNVHEGKLLGCSYNQNCVGVWVVDLSRTEPMSGGATQ----SNSHPEKTSGSGRD 324

  Fly   371 --GASDNPS--VLTRSDSFIPDIWAAEVTVQERAIRQNRARVSNNHVSGYNFVYAISSGVLP--L 429
              |.:||.|  :|.:    :|.....:..::|.. ...:..||.|            |..||  .
plant   325 QAGLNDNSSKVILGK----LPGSQKVDPLLKETK-SLGKLSVSQN------------SDPLPKDT 372

  Fly   430 RQLGANSLMGSS----TSPRPLTTPPPTESNQSSSSSSSSSSSSSSSSSSNNSDTTVRLEIGNRL 490
            :..|.:|:..||    ..|:||.....|.|:.:...|.:.||:.|.|.|.:....|...:..:.:
plant   373 KSTGRSSVSQSSDPLVKEPKPLGRFSATHSSDTVKESRTLSSTGSVSDSPHRVTLTSAPKSASGI 437

  Fly   491 RL---------RSF-------NSPVTTPTFKENGHSILV-NAKKLLYYAAETNTKPGFIKEPGFS 538
            ..         |:|       |.||..   ||:...::| ..:.::..|:|:..:...|
plant   438 STVVPNAAASKRNFGKANPKANPPVVN---KEDYFPVIVPRTEPIIEQASESRAELDII------ 493

  Fly   539 ADGRVVCSPY-----GNGVRLFGYSEDCCDYPKCQAFEEVKSKPRKLVEL 583
              ||.:  ||     ....|....|.:..|.|.....|..:|:|.:.:.|
plant   494 --GRTM--PYSLQSKAADSRRLSSSRNEPDLPTSSLLERSQSQPIEPITL 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1523	NP_651635.2	WD40	43..235	CDD:295369	38/196 (19%)
		WD40	<45..>218	CDD:225201	38/179 (21%)
		WD40 repeat	51..87	CDD:293791	2/5 (40%)
		WD40 repeat	95..129	CDD:293791	10/35 (29%)
		WD40 repeat	136..174	CDD:293791	7/76 (9%)
		WD40 repeat	181..210	CDD:293791	7/28 (25%)
AT5G08390	NP_568194.2	WD40	9..261	CDD:238121	54/306 (18%)
		WD40 repeat	63..99	CDD:293791	5/35 (14%)
		WD40 repeat	104..140	CDD:293791	2/35 (6%)
		WD40 repeat	147..182	CDD:293791	13/63 (21%)
		WD40 repeat	188..222	CDD:293791	6/33 (18%)
		Katanin_con80	680..831	CDD:404758
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910