DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1523 and WDR55

DIOPT Version :9

Sequence 1:	NP_651635.2	Gene:	CG1523 / 43400	FlyBaseID:	FBgn0039601	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_565782.1	Gene:	WDR55 / 817987	AraportID:	AT2G34260	Length:	353	Species:	Arabidopsis thaliana

Alignment Length:	194	Identity:	48/194 - (24%)
Similarity:	88/194 - (45%)	Gaps:	23/194 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 HIHRSD-DNSLMRRIYSSMNMFNSYHANCWPTDAGRTGAIFNLEFNADGNVVVAATERKCVLVFD 76
            |::|.| |:||:|.     ....::..:|..           :.|..||..:|.|:....:|..|
plant    31 HLYRYDSDSSLVRE-----RKVRAHKESCRA-----------VRFIDDGQRIVTASADCSILATD 79

  Fly    77 AITQKEIFKVPDAHTDSVNCIKFFDERLFATGSDDFTVALWDLRNMKQKLRVLHGHSNWVKNIEY 141
            ..|..::..:.:||.|:||.:....|...|:|.|...|.:||.| .:......:.|.:::..:.:
plant    80 VETGAQVAHLENAHEDAVNTLINVTETTIASGDDKGCVKIWDTR-QRSCSHEFNAHEDYISGMTF 143

  Fly   142 SSKD-KLLVSSGFDGSIFTWDINSQTEQGLISQRVFHASGLMRCRISPTGDKLVLCTSGGYIMI 204
            :|.. ||:|:|| ||::...::.:...|   ||..|....|:...|...|.|::..|..|.:::
plant   144 ASDSMKLVVTSG-DGTLSVCNLRTSKVQ---SQSEFSEDELLSVVIMKNGRKVICGTQNGTLLL 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1523	NP_651635.2	WD40	43..235	CDD:295369	40/163 (25%)
		WD40	<45..>218	CDD:225201	40/161 (25%)
		WD40 repeat	51..87	CDD:293791	8/35 (23%)
		WD40 repeat	95..129	CDD:293791	9/33 (27%)
		WD40 repeat	136..174	CDD:293791	10/38 (26%)
		WD40 repeat	181..210	CDD:293791	6/24 (25%)
WDR55	NP_565782.1	WD40	12..290	CDD:392136	48/194 (25%)
		WD40 repeat	12..49	CDD:293791	7/22 (32%)
		WD40 repeat	54..90	CDD:293791	9/46 (20%)
		WD40 repeat	98..132	CDD:293791	9/34 (26%)
		WD40 repeat	138..176	CDD:293791	11/41 (27%)
		WD40 repeat	224..246	CDD:293791
		WD40 repeat	265..289	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910