DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1523 and LUH

DIOPT Version :9

Sequence 1:	NP_651635.2	Gene:	CG1523 / 43400	FlyBaseID:	FBgn0039601	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_001189659.1	Gene:	LUH / 817830	AraportID:	AT2G32700	Length:	806	Species:	Arabidopsis thaliana

Alignment Length:	306	Identity:	64/306 - (20%)
Similarity:	109/306 - (35%)	Gaps:	86/306 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RRESGFHIHRSDDNSLMRRIYSSMNMFNSYHANCWPTDAGRTGAIFNLEFNADGNVVVAATERKC 71
            :|.|..|...|...|           ||  ..:|....|.:   :....|:.||.::.:|...|.
plant   504 KRNSSVHTETSKPFS-----------FN--EVSCIRKSASK---VICCSFSYDGKLLASAGHDKK 552

  Fly    72 VLVFDAITQKEIFKVPDAHTDSVNCIKFF-DERLFATGSDDFTVALWDLRNMKQKLRVLHGHSNW 135
            |.:::..| .::...|:.|...:..::|. :....||.|.|.|:.:||..:....||.:.||:..
plant   553 VFIWNMET-LQVESTPEEHAHIITDVRFRPNSTQLATSSFDKTIKIWDASDPGYFLRTISGHAAP 616

  Fly   136 VKNIEY-SSKDKLLVSSGFDGSIFTWDINSQTEQGLISQRVFHASGLMRCRISPTGDKLVLCTSG 199
            |.:|:: ..|.:||.|...:..|..||||:...:.     |..||..:|
plant   617 VMSIDFHPKKTELLCSCDSNNDIRFWDINASCVRA-----VKGASTQVR---------------- 660

  Fly   200 GYIMIIHHLDLTTLHKDLCGFRPGIYRLMQLGEQYIPQAAKYD-HVFSKRQKKNRVELVTDFPEN 263
                                |:|      :.| |::..|::.. .:|.......||.:......|
plant   661 --------------------FQP------RTG-QFLAAASENTVSIFDIENNNKRVNIFKGHSSN 698

  Fly   264 NDAEMIMALQIHPHCCC---MLTRNVSCDEQSEWT-----CIHDIN 301
                      :|..|..   .|..:||.|....|:     |||:::
plant   699 ----------VHSVCWSPNGELVASVSEDAVKLWSLSSGDCIHELS 734

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1523	NP_651635.2	WD40	43..235	CDD:295369	41/193 (21%)
		WD40	<45..>218	CDD:225201	37/174 (21%)
		WD40 repeat	51..87	CDD:293791	7/35 (20%)
		WD40 repeat	95..129	CDD:293791	10/34 (29%)
		WD40 repeat	136..174	CDD:293791	11/38 (29%)
		WD40 repeat	181..210	CDD:293791	1/28 (4%)
LUH	NP_001189659.1	LisH	10..36	CDD:285685
		WD40	521..806	CDD:238121	57/276 (21%)
		WD40	521..>806	CDD:225201	57/276 (21%)
		WD40 repeat	534..569	CDD:293791	8/35 (23%)
		WD40 repeat	575..612	CDD:293791	10/36 (28%)
		WD40 repeat	617..654	CDD:293791	12/41 (29%)
		WD40 repeat	659..692	CDD:293791	9/75 (12%)
		WD40 repeat	699..734	CDD:293791	10/34 (29%)
		WD40 repeat	742..775	CDD:293791
		WD40 repeat	781..805	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910